Risk Factors for Recurrent Hypoglycemia in Hospitalized Diabetic Patients Admitted for Severe Hypoglycemia

Purpose: Severe hypoglycemia can result in neural damage, impaired cognitive function, coma, seizures, or death. The decision to admit diabetic patients after initial treatment in the emergency department remains unclear. Our purpose is to identify risk factors for developing recurrent hypoglycemia in diabetic patients admitted for severe hypoglycemia. Materials and Methods: We reviewed the records of 233 subjects (92 males, 141 females; mean age, 74.1 ± 9.8 years) with type 2 diabetes treated at a tertiary care teaching hospital and hospitalized for severe hypoglycemia. Results: Seventy-four (31.8%) patients were categorized with recurrent hypoglycemia and 159 (68.2%) with non-recurrent. Multivariate logistic regression analysis revealed that patients with loss of a recent meal, coronary artery disease, infection, and poor renal function (lower estimated glomerular filtration rate) were at risk for recurrent hypoglycemia. The use of calcium-channel blockers appeared to be a protective factor for the development of recurrent hypoglycemia. Conclusion: There may be a subset of patients with severe hypoglycemia and certain risk factors for recurrent hypoglycemia that should be admitted

En las fronteras del imperio: Jerónimo Corte Real y la épica luso-castellana

Jerónimo Corte Real († 1588), fue bisnieto del navegador João Vaz Corte Real, nieto de Gaspar Corte Real, que sirvió al Rey D. Manuel I en Africa, e hijo segundo de Manuel Corte Real, donatario de capitanías azorianas e hidalgo de la Casa Real. Su madre fue Da. Brites de Mendoza, dama de la reina Da. Catarina, castellana como ella, y vástaga de una familia aristocrática allegada a la monarquía portuguesa por su largo servicio militar y marino. El poeta se casó en 1561 con Da. Luisa da Silva, ..