63 research outputs found

    Secure Communication for Spatially Sparse Millimeter-Wave Massive MIMO Channels via Hybrid Precoding

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    In this paper, we investigate secure communication over sparse millimeter-wave (mm-Wave) massive multiple-input multiple-output (MIMO) channels by exploiting the spatial sparsity of legitimate user's channel. We propose a secure communication scheme in which information data is precoded onto dominant angle components of the sparse channel through a limited number of radio-frequency (RF) chains, while artificial noise (AN) is broadcast over the remaining nondominant angles interfering only with the eavesdropper with a high probability. It is shown that the channel sparsity plays a fundamental role analogous to secret keys in achieving secure communication. Hence, by defining two statistical measures of the channel sparsity, we analytically characterize its impact on secrecy rate. In particular, a substantial improvement on secrecy rate can be obtained by the proposed scheme due to the uncertainty, i.e., 'entropy', introduced by the channel sparsity which is unknown to the eavesdropper. It is revealed that sparsity in the power domain can always contribute to the secrecy rate. In contrast, in the angle domain, there exists an optimal level of sparsity that maximizes the secrecy rate. The effectiveness of the proposed scheme and derived results are verified by numerical simulations

    Discrete double integrator consensus

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    A distributed double integrator discrete time consensus protocol is presented along with stability analysis. The protocol will achieve consensus when the communication topology contains at least a directed spanning tree. Average consensus is achieved when the communication topology is strongly connected and balanced, where average consensus for double integrator systems is discussed. For second order systems average consensus occurs when the information states tend toward the average of the current information states not their initial values. Lastly, perturbation to the consensus protocol is addressed. Using a designed perturbation input, an algorithm is presented that accurately tracks the center of a vehicle formation in a decentralized manner

    Utility of whole-genome sequencing during an investigation of multiple foodborne outbreaks of Shigella sonnei

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    In April 2018, Public Health England was notified of cases of Shigella sonnei who had eaten food from three different catering outlets in England. The outbreaks were initially investigated as separate events, but whole-genome sequencing (WGS) showed they were caused by the same strain. The investigation included analyses of epidemiological data, the food chain and microbiological examination of food samples. WGS was used to determine the phylogenetic relatedness and antimicrobial resistance profile of the outbreak strain. Ultimately, 33 cases were linked to this outbreak; the majority had eaten food from seven outlets specialising in Indian or Middle Eastern cuisine. Five outlets were linked to two or more cases, all of which used fresh coriander although a shared supplier was not identified. An investigation at one of the venues recorded that 86% of cases reported eating dishes with coriander as an ingredient or garnish. Four cases were admitted to hospital and one had evidence of treatment failure with ciprofloxacin. Phylogenetic analysis showed that the outbreak strain was part of a wider multidrug-resistant clade associated with travel to Pakistan. Poor hygiene practices during cultivation, distribution or preparation of fresh produce are likely contributing factors

    Fluorescence measurements of immune complexes of Mab 4-4-20 with isomeric haptens.

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    Relative differences in the active site environment of a monoclonal antibody when covalently bound to two isomeric haptens were studied using fluorescence quenching and lifetime measurements. Murine monoclonal antibody 4-4-20, a well-characterized high affinity antifluorescein antibody, served as the model IgG protein. Isomeric haptenic probes comparatively studied were fluorescein-5-isothiocyanate (FITC I, the immunogen) and fluorescein-6-isothiocyanate (FITC II). In kinetic binding studies, the association rate for the interaction of 4-4-20 with FITC I was greater than 2,000 times faster than the reaction with FITC II. Fluorescence lifetimes for FITC I covalently bound to 4-4-20 were 3.89 ns and 0.37 ns, indicative of hapten bound outside and inside the active site, respectively. Fluorescence lifetime for FITC II within the active site was indistinguishable from bound FITC I, indicating that interactions with active site residues which resulted in a decreased lifetime were similar for both isomers. A decreased lifetime for active site bound FITC I was consistent with the 90-95% quenching of fluorescein fluorescence. Dynamic fluorescence quenching experiments with iodide and FITC I in the active site showed no solvent accessibility, whereas bound FITC II showed significant accessibility. These results suggest that the difference in bond angle which accompanies binding of isomer II relative to isomer I within the active site probably leads to steric constraints resulting in a more open configuration of the 4-4-20 active site

    Acoustic Emission from Microcracks during Sliding Contact

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