Gamma rays of 0.3 to 30 MeV from PSR 0531+21

Pulsed gamma rays from the Crab Pulsar PSR 0531+21 are reported for energies of 0.3 to 30 MeV. The observations were carried out with the UCR gamma ray double Compton scatter telescope launched on a balloon from Palestine, Texas at 4.5 GV, at 2200 LT, September 29, 1978. Two 8 hr observations of the pulsar were made, the first starting at 0700 UT (0200 LT) September 30 just after reaching float altitude of 4.5 g/sq cm. Analysis of the total gamma ray flux from the Crab Nebula plus pulsar using telescope vertical cell pairs was published previously. The results presented supersede the preliminary ones. The double scatter mode of the UCR telescope measures the energy of each incident gamma ray from 1 to 30 MeV and its incident angle to a ring on the sky. The time of arrival is measured to 0.05 ms. The direction of the source is obtained from overlapping rings on the sky. The count rate of the first scatter above a threshold of 0.3 MeV is recorded every 5.12 ms. The Crab Pulsar parameters were determined from six topocentric arrival times of optical pulses

Derivation of a dynamic model of the kinetics of nitrogen uptake throughout the growth of lettuce : calibration and validation

A kinetic model of nitrogen (N) uptake throughout growth was developed for lettuce cultivated in nutrient solution under varying natural light conditions. The model couples nitrogen uptake with dry matter accumulation using a two-compartment mechanistic approach, incorporating structural and non-structural pools. Maximum nitrogen uptake rates are assumed to decline with shoot dry weight, to allow for the effects of plant age. The model was parameterized using data from the literature, and calibrated for differences in light intensity using an optimization algorithm utilizing data from three experiments in different growing seasons. The calibrated model was validated against the data from two independent experiments conducted under different light conditions. Results showed that the model made good predictions of nitrogen uptake by plants from seedlings to maturity under fluctuating light levels in a glasshouse. Plants grown at a higher light intensity showed larger maximum nitrogen uptake rates, but the effect of light intensity declined towards plant maturity

University of Strathclyde at TREC HARD

The motivation behind the University of Strathclyde's approach to this years HARD track was inspired from previous experiences by other participants, in particular research by [1], [3] and [4]. A running theme throughout these papers was the underlying hypothesis that a user's familiarity in a topic (i.e. their previous experience searching a subject), will form the basis for what type or style of document they will perceive as relevant. In other words, the user's context with regards to their previous search experience will determine what type of document(s) they wish to retrieve

Functional consequences for primary human alveolar macrophages following treatment with long, but not short, multiwalled carbon nanotubes

Sinbad Sweeney, Davide Grandolfo, Pakatip Ruenraroengsak, Teresa D TetleyLung Cell Biology, Section of Pharmacology and Toxicology, National Heart and Lung Institute, Imperial College London, London, UKPurpose: Multiwalled carbon nanotubes (MWCNTs) are a potential human health hazard, primarily via inhalation. In the lung, alveolar macrophages (AMs) provide the first line of immune cellular defense against inhaled materials. We hypothesized that, 1 and 5 days after treating AMs with short (0.6 µm in length; MWCNT-0.6 µm) and long (20 µm in length; MWCNT-20 µm) MWCNTs for 24 hours, AMs would exhibit increased markers of adverse bioreactivity (cytokine release and reactive oxygen species generation) while also having a modified functional ability (phagocytosis and migration).Methods: Primary human AMs were treated with short and long MWCNTs for 24 hours, 1 and 5 days after which toxicity end points, including cell death, reactive oxygen species generation, and inflammatory mediator release, were measured. AM functional end points involving phagocytic ability and migratory capacity were also measured.Results: AM viability was significantly decreased at 1 and 5 days after treatment with MWCNT-20 µm, while superoxide levels and inflammatory mediator release were significantly increased. At the same time, there was reduced phagocytosis and migratory capacity alongside increased expression of MARCO; this coincided with frustrated phagocytosis observed by scanning electron microscopy. In contrast, the adverse bioreactivity of the shorter MWCNT-0.6 µm with AMs (and any resulting reduction in AM functional ability) was substantially less marked or absent altogether.Conclusion: This study shows that after 24-hour treatment with long, but not short, MWCNTs, AM function is severely affected up to 5 days after the initial exposure. This has potentially significant pathophysiological consequences for individuals who may be intentionally (via therapeutic applications) or unintentionally exposed to these nanomaterials.Keywords: nanotechnology, MWCNTs, alveolar macrophages, cytokines, phagocytosis, bioreactivit

Measured performance of the new University of California gamma ray telescope

The design of the new medium energy balloon-borne gamma ray telescope is discussed. This telescope is sensitive to 1-30 MeV gamma rays. The results of the initial calibration are described. The position and energy resolutions of 32 plastic and NaI(Tl) scintillator bars, each 100 cm long are discussed. The telescope's measured angular and energy resolutions as a function of incident angle are compared with detailed Monte Carlo calculations at 1.37, 2.75 and 6.13 MeV. The expected resolutions are 5 deg FHWM and 8% at 2.75 MeV. The expected area-efficiency is 250 cm

Assessing the fidelity of delivery of an intervention to increase attendance at the English Stop Smoking Services

Background: Implementation fidelity refers to the extent to which a proposed intervention is enacted as designed and is necessary to determine how much the intervention in question is the primary mechanism in any changes observed. Start2quit was a randomised controlled trial that aimed to improve attendance at the English Stop Smoking Service (SSS). The complex intervention combining computer-tailored personal risk letters and no-commitment (“taster”) sessions aimed at encouraging attendance at the SSS doubled attendance at the SSS and significantly increased abstinence rates, although attendance and abstinence varied between participating SSSs. Assessment of the fidelity of the delivery of the taster sessions to the protocol was embedded into the trial and is the focus of this study. / Methods: Eighteen SSSs participated in the study. Taster sessions were delivered by SSS advisors in the area. Of the 131 sessions delivered, 93 (71 %) were recorded and 41 (31.3 %) were selected for transcription and analysis. The taster session protocol contained 73 specified behaviours, which were independently classified into component behaviour change techniques (BCTs) using an established taxonomy for smoking cessation. All transcripts were coded by two authors with 25 % additionally coded by a third. The fidelity of each taster session was expressed as the percentage of overall protocol-specified behaviours that were delivered. Adherence to each BCT was measured as the number of behaviours applied by the advisors within each BCT divided by the total number classified within each. / Results: Adherence of protocol-specified behaviours was relatively high (median 71.23 %), though there was considerable variation (28.76 to 95.89 %) in individual sessions. Median fidelity to specific BCTs across sessions also varied from 50 to 100 %. Shorter sessions, sessions run jointly by two advisors, by female advisors, or by advisors aged 45 to 54 were associated with higher levels of adherence. There was no association between adherence and subsequent attendance at the SSS. / Conclusions: These results suggest that the delivery of the intervention of this study is not likely to have been impacted by issues of fidelity. As such, we can have greater confidence that variability in the main outcome is not due to variability in SSS advisor adherence to the protocol of the taster sessions. / Trial registration: Current Controlled Trials ISRCTN7656191

Characterization of aggregate behaviors of torrefied biomass as a function of reaction severity

Several studies have shown that torrefaction can improve various characteristics of biomass, including grindability, flowability, and energy density, at least at the microscopic level. Furthermore, the improvements are often represented as a monotonic function of the torrefaction severity. However, the existing literature is less clear on whether or not these improvements persist at the aggregate level. This paper demonstrates that, at the aggregate level, using differently torrefied biomass in an experimental cookstove as a case study, the relationship between the improvements and torrefaction severity tells a much more complex story than a simple, monotonic correlation. Notably, by defining and measuring various cookstove performance characteristics ranging from stove temperature, effective heat output, and emission profiles, and how these characteristics vary with the severity of torrefied fuel, we conclude that, contrary to the conventional wisdom, more severe torrefaction in many cases does not always lead to more improved fuel characteristics

Diversity and inclusion depend on effective engagement It is everyone’s business to ensure that progress is maintained

Purpose – Highlights some of the things that can be done to ensure that organizations embed diversity and inclusion. Design/methodology/approach – Considers the need for effective engagement, the importance of performance indicators for diversity and inclusion and the key role of sharing stories. Discusses, too, how critical race theory could help to bring about improvements. Findings – Advances the view that a transformational process that supports employees with the knowledge and sustainable skills needed to improve business performance via ethical means will form a significant part of future-proofing organizations. Practical implications – Argues that, to achieve this organizations have to drive home the message that diversity and inclusion are everyone’s business. Social implications – Advances the view that a unified approach to diversity and inclusion, which is embedded in the business ethics of the organization, can have a sustainable positive impact on the health and well-being of individuals, business and society. Originality/value – Considers diversity and inclusion from diverse perspectives and draws conclusions that can help organizations to perform better in these areas