Radiation counting technique allows density measurement of metals in high-pressure/ high-temperature environment

Radioactive tracers induced by neutron irradiation provide a gamma ray flux proportional to the density of a metal, allowing density measurement of these metals in extreme high-temperature and high-pressure environments. This concept is applicable to most metals, as well as other substances

Investigations of electron emission characteristics of low work function surfaces Final report, 27 Sep. 1964 - 28 Sep. 1966

Electron emission characteristics of low work function surface

Investigations of electron emission characteristics of low work function surfaces Quarterly report, 28 Sep. - 27 Dec. 1966

Coadsorption of cesium and fluorine on tungsten, and analysis of mechanisms leading to decay of field emission current from low work function zirconium/oxygen coated tungsten emitte

Friction factors for smooth pipe flow

Friction factor data from two recent pipe flow experiments are combined to provide a comprehensive picture of the friction factor variation for Reynolds numbers from 10 to 36,000,000

World Language Teacher Candidate Performance on edTPA: An Exploratory Study

Federal and state legislation continues to promote teacher accountability in the United States. The new edTPA, a subject-specific teacher performance assessment, is purported to measure beginning teacher readiness and is being pilot tested and implemented for licensure and certification decisions across the country. In this exploratory quantitative study, the researchers examined edTPA scores of 21 world language teacher candidates from two teacher preparation programs and compared those results to the cut scores for the states of Washington and New York. Results indicated that participants performed best in the planning section and were most challenged by the assessment section. This research has implications for teacher certification candidates, world language teacher preparation programs, policy makers, and other stakeholders

Re-examining teacher candidate performance on world language edTPA as a consequential assessment

Used by almost 800 educator preparation programs in more than 40 states and the District of Columbia, edTPA seeks to measure content-specific outcomes of beginning teachers as a high-stakes assessment. Many states also use edTPA to inform teacher licensure or certification decisions, making the assessment consequential for individual teacher candidates. The present study focuses on teacher candidates’ performance on the World Language edTPA, targeting two world language teacher education programs since the assessment became consequential for licensure in their respective states. It then compares findings to those of a previous study of the same programs’ World Language edTPA performance (Hildebrandt & Swanson, 2014) from before the assessment became consequential for teacher licensure decisions in 2015 in [State X] and [State Y]. Programmatic changes were implemented after initial inspection of the data and results from such curricular changes are discussed in terms of local impact. Additionally, national trends are identified and discussed. Findings demonstrate serious issues regarding this assessment of beginning teacher effectiveness as related to World Language teaching and learning. This research has implications for teacher preparation programs and other educational stakeholders alike

Modalities for Imaging of Prostate Cancer

Prostate cancer is the second most common cause of cancer deaths among males in the United States. Prostate screening by digital rectal examination and prostate-specific antigen has shifted the diagnosis of prostate cancer to lower grade, organ confined disease, adding to overdetection and overtreatment of prostate cancer. The new challenge is in differentiating clinically relevant tumors from ones that may otherwise never have become evident if not for screening. The rapid evolution of imaging modalities and the synthesis of anatomic, functional, and molecular data allow for improved detection and characterization of prostate cancer. However, the appropriate use of imaging is difficult to define, as many controversial studies regarding each of the modalities and their utilities can be found in the literature. Clinical practice patterns have been slow to adopt many of these advances as a result. This review discusses the more established imaging techniques, including Ultrasonography, Magnetic Resonance Imaging, MR Spectroscopy, Computed Tomography, and Positron Emission Tomography. We also review several promising techniques on the horizon, including Dynamic Contrast-Enhanced MRI, Diffuse-Weighted Imaging, Superparamagnetic Nanoparticles, and Radionuclide Scintigraphy

Investigations of electron emission characteristics of low work function surfaces Final report, 28 Sep. 1966 - 13 Nov. 1967

Electron emission characteristics of low work function surface

Volume 2 - Literature review of adsorption on metal surfaces Final report, 1 May 1966 - 2 Jul. 1967

Atom and ion desorption energy, chemisorption theory and surface bonds, work functions and potential energy in literature review of adsorption on metal surface

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection.

To restrict infection by Legionella pneumophila, mouse macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich repeat family of pattern recognition receptors, which detect cytoplasmic microbial products. We report that mouse macrophages restricted L. pneumophila replication and initiated a proinflammatory program of cell death when flagellin contaminated their cytosol. Nuclear condensation, membrane permeability, and interleukin-1beta secretion were triggered by type IV secretion-competent bacteria that encode flagellin. The macrophage response to L. pneumophila was independent of Toll-like receptor signaling but correlated with Naip5 function and required caspase 1 activity. The L. pneumophila type IV secretion system provided only pore-forming activity because listeriolysin O of Listeria monocytogenes could substitute for its contribution. Flagellin monomers appeared to trigger the macrophage response from perforated phagosomes: once heated to disassemble filaments, flagellin triggered cell death but native flagellar preparations did not. Flagellin made L. pneumophila vulnerable to innate immune mechanisms because Naip5+ macrophages restricted the growth of virulent microbes, but flagellin mutants replicated freely. Likewise, after intratracheal inoculation of Naip5+ mice, the yield of L. pneumophila in the lungs declined, whereas the burden of flagellin mutants increased. Accordingly, macrophages respond to cytosolic flagellin by a mechanism that requires Naip5 and caspase 1 to restrict bacterial replication and release proinflammatory cytokines that control L. pneumophila infection