Four-gap glass RPC as a candidate to a large area thin time-of-flight detector

A four-gap glass RPC with 0.3mm gap size was tested with hadron beam as a time-of-flight detector having a time resolution of ~ 100ps. A thickness of the detector together with front-end electronics is ~ 12mm. Results on time resolution dependently on a pad size are presented. This paper contains first result on the timing RPC (with ~ 100ps resolution) having a strip read-out. Study has been done within the HARP experiment (CERN-PS214) R&D work. A obtaned data can be useful if a design of a large area thin timing detector has to be done.Comment: 18 pages, 13 figure

In memoriam two distinguished participants of the Bregenz Symmetries in Science Symposia: Marcos Moshinsky and Yurii Fedorovich Smirnov

Some particular facets of the numerous works by Marcos Moshinsky and Yurii Fedorovich Smirnov are presented in these notes. The accent is put on some of the common interests of Yurii and Marcos in physics, theoretical chemistry, and mathematical physics. These notes also contain some more personal memories of Yurii Smirnov.Comment: Submitted for publication in Journal of Physics: Conference Serie

RPC with low-resistive phosphate glass electrodes as a candidate for the CBM TOF

Usage of electrodes made of glass with low bulk resistivity seems to be a promising way to adapt the Resistive Plate Chambers (RPC) to the high-rate environment of the upcoming CBM experiment. A pilot four-gap RPC sample with electrodes made of phosphate glass, which has bulk resistivity in the order of 10^10 Ohm cm, has been studied with MIP beam for TOF applications. The tests have yielded satisfactory results: the efficiency remains above 95% and the time resolution stays within 120 ps up to the particle rate of 18 kHz/cm2. The increase in rate from 2.25 to 18 kHz/cm2 leads to an increase of estimated "tails" fraction in the time spectrum from 1.5% to 4%.Comment: 8 pages, 6 figures, submitted to Elsevier Scienc

Why the paper CERN-PH-EP-2009-015 (arXiv:0903.4762) is scientifically unacceptable

The paper CERN-PH-EP-2009-015 (arXiv:0903.4762) by A. Bagulya et al. violates standards of quality of work and scientific ethics on several counts. The paper contains assertions that contradict established detector physics. The paper falls short of proving the correctness of the authors' concepts and results. The paper ignores or quotes misleadingly pertinent published work. The paper ignores the fact that the authors' concepts and results have already been shown wrong in the published literature. The authors seem unaware that cross-section results from the 'HARP Collaboration' that are based on the paper's concepts and algorithms are in gross disagreement with the results of a second analysis of the same data, and with the results of other experiments.Comment: 8 pages, 3 figure

In-vivo Studies of Ultrasound-activated Drug-loaded Porous Silicon Nanoparticles for Cancer Therapy Application

It is investigated the therapeutic efficacy of combined action of ultrasound and porous silicon nanoparticles loaded with anticancer drug doxorubicin by using an experimental cancer model of lung Lewis carcinoma in vivo. Time dependences of growth of the primary tumor with introduced nanoparticles and without them, as well as the life span of mice after exposure to therapeutic ultrasound with intensity of 1W/cm2 and frequency of 1 MHz were studied. The obtained results show the effectiveness of inhibiting the growth of primary tumor site, as well as slowing the process of metastasis, in the case of combined action of ultrasound and drug-loaded porous silicon nanoparticles that indicates the prospect of latter as sonosensitizers and nanocontainers for the delivery and controlled release of drugs in sonodynamic therapy of malignant tumors. Keywords: silicon nanoparticles, nanocontainers, medical ultrasound, sonodynamic therapy, sonosensitizer

Comparison of Geant4 hadron generation with data from the interactions with beryllium nuclei of +8.9 GeV/c protons and pions, and of -8 GeV/c pions

Hadron generation in the Geant4 simulation tool kit is compared with inclusive spectra of secondary protons and pions from the interactions with beryllium nuclei of +8.9 GeV/c protons and pions, and of -8.0 GeV/c pions. The data were taken in 2002 at the CERN Proton Synchrotron with the HARP spectrometer. We report on significant disagreements between data and simulated data especially in the polar-angle distributions of secondary protons and pions.Comment: 15 pages, 13 figure