A LABEL-FREE VOLTAMPEROMETRIC SENSOR BASED ON ELECTRIC CONDUCTIVE POLYMER COATINGS OF 3,4-ETHYLENEDIOXYTHIOPHENE / 3-ETHYNYLTHIOPHENE FOR DETERMINATION OF E.COLI AND S.AUREUS

This work was supported by a grant from the President of the Russian Federation for young scientists - candidates of sciences MK-567.2020.3

SMALL ORGANIC MOLECULES FOR SELECTIVE ELECTROCHEMICAL DETERMINATION OF NITROAROMATIC COMPOUNDS

The work was carried out with the financial support of the Russian Science Foundation grant No. 20-13-00142

Determination of E. Coli in Water Using the Enzyme Free Electrochemical Impedimetric Immunosensors

In this article, we have shown the results of E. coli bacteria determination in water using the enzyme free electrochemical immunosensor with covalent via click chemistry immobilized receptor layer in comparison with dropwise immobilized antibodies. Covalent immobilization was realized by creating precursors on the surface of the working electrode with the reaction of azide-alkyne copper-catalysed cycloaddition approach. The detection limit of the immunosensor with covalent and dropwise immobilization of antibodies was estimated as 6.6 CFU/ml and 11.2 CFU/ml, respectively, a linear range was 103-106 CFU/ml. Moreover, the sensor with "click"immobilized antibodies showed good stability for 30 days when stored in a phosphate buffer, while the sensor with dropwise immobilized receptor layer was stable for 3 days. © Published under licence by IOP Publishing Ltd.This work was supported by the Presidential Grants Fund of the Russian Federation (grant MK-567.2020.3)

Electrochemical Behavior of Chloramphenicol on Carbon-Containing Electrodes in a Microcell

The work is devoted to the study of the electrochemical behavior of chloramphenicol during the transition from a macro- to a microcell. The possibility of using the reduction of the nitro group as an analytical signal for the determination of CA in a microcell was shown.Работа выполнена при финансовой поддержке гранта МК-392.2022.1.3

PENTAFLUOROPHENYL-2H-IMIDAZOLE DERIVATIVES OF CARBAZOLE BASED MOLECULARLY IMPRINTED POLYMER FOR CHLORAMPHENICOL DETECTION: CREATION AND PROPERTIES

In this work the creation and characterization of molecularly imprinted polymer based on pentafluorophenyl-2H-imidazole derivatives of carbazole for chloramphenicol detection have been investigated. The increased direct electrochemical response of chloramphenicol on modified electrodes was shown.Работа выполнена при финансовой поддержке гранта РНФ № 20-73-10077

TECHNOLOGY OF PREPARING CONJUGATES OF MAGNETITE NANOPARTICLES WITH ANTIBODY CONJUGATES FOR QUANTITATIVE DETERMINATION OF MEASLES VIRUS ANTIGEN BY ELECTROCHEMICAL IMMUNOASSAY

The present work is devoted to development of approach for the determination of antigens of viruses, which consist in producing an electrochemical signal from the immunocomplex "target analyte (antigen) - conjugate antibodies and nanoparticles Fe3O4», localized on the surface of the electrode. Amino modified nanoparticles magnetite and their conjugates with measles virus antibodies were synthesizedin order to implement the approach

ELECTROCHEMICAL DETERMINATION OF NITROBENZENE IN HONEY SAMPLES ON A GLASS-CARBON ELECTRODE MODIFIED WITH CNT AND DERIVATIVES OF 1,3- / 1,4-DIAZINES

In this work, the effect of modification of a glassy carbon electrode with CNTs and 1,3-1,4-diazine derivatives on the electrochemical reduction of nitrobenzene was investigated

PHOTOPHYSICAL PROPERTIES OF PENTAFLUORO-ARYL-2H-IMIDAZOLES AND THEIR APPLICATION AS PH-SENSITIVE FLUOROPHORS FOR DETERMINING THE ACIDITY OF SALIVA

In the course of the work, the photophysical properties of pentafluoro-aryl-2H-imidazoles in aqueous-organic systems with varying pH values and organic phase content were studied. The possibility of using it as sensor molecules for determining the pH of human saliva has been shown.Исследования выполнены при финансовой поддержке Российского научного фонда в рамках проекта 20-73-10077

STRUCTURING OF THE SENSOR RECEPTOR LAYER TO CHLORAMPHENICOL BY ELECTRODEPOSITION OF 3,6-BIS(ETHYNYL)-9Н-CARBAZOLE

In this work, the approach to structuring the receptor layer of the glassy carbon electrode by electropolymerization of 3,6-bis(ethynyl)-9H-carbazole through the acetylene fragment has been proposed. The use of immobilized molecule as an agent for selective detection of chloramphenicol was evaluated.Работа выполнена при финансовой поддержке гранта МК-392.2022.1.3

Fluorometric Determination of Chloramphenicol in Aqueous Solutions Using Derivatives of 9h-Carbazole

На сегодняшний день задачей экологического мониторинга является детектирование следовых количеств антибиотиков в объектах окружающей среды и продуктах питания. Настоящее исследование посвящено сравнительной оценке возможности применения замещенных и незамещенных карбазолов для флуорометрического определения хлорамфеникола в водно-органических растворах. Показано закономерное изменение интенсивности флуоресценции, обусловленное процессами взаимодействия исследуемых флуорофоров с аналитом. Наиболее перспективным соединением для аналитического применения является ацетиленпроизводное карбазола, продемонстрировавшее в широком линейном диапазоне (0,1-25 мкМ) высокую чувствительность Ksv=105425 M-1 с пределом обнаружения 2,8 мкМ.Today, the task of environmental monitoring is to detect trace amounts of antibiotics in environmental objects and food. The present study is devoted to a comparative assessment of the possibility of using substituted and unsubstituted carbazoles for the fluorometric determination of chloramphenicol in aqueous organic solutions. A regular change in the fluorescence intensity caused by the processes of interaction of the studied fluorophores with the analyte is shown. The most prospects compound for analytical use is the acetylene derivative of carbazole, showing in a wide linear range (0,1-25 μM) a high sensitivity of Ksv=105425 M-1 with a detection limit 2,8 μM