Transition from regular to chaos from the aspect of nodal domains associated with wave functions(2) Equilibrium and nonequilibrium statistical mechanics in systems showing chaos and quantum chaos, Chaos and Nonlinear Dynamics in Quantum-Mechanical and Macroscopic Systems)

この論文は国立情報学研究所の電子図書館事業により電子化されました。2次元4次振動子模型を用いて、系のダイナミクスが可積分からカオスまで変化するとき、波動関数の結節構造がどう変化するかを、結節領域の数、結節線と古典運動の境界との交点数、結節領域の面積分布の指標を用いて調べた

Plasmid Curing is a Promising Approach to Improve Thermophiles for Biotechnological Applications: Perspectives in Archaea

Thermophiles are attractive as host cells for microbial processes to produce or degrade various compounds. In these applications, it is often desirable to improve the properties of thermophiles, such as their growth rate, cell density, and protein productivity, although this is rarely achieved because of the lack of general approaches. In this chapter, we describe the elimination of the pHTA426 plasmid from a moderate thermophile, Geobacillus kaustophilus HTA426, and its effects on the microbial properties. This process, called plasmid curing, was simply achieved using a DNA intercalator and confirmed by phenotypic and genotypic analyses. Of note, pHTA426 curing had beneficial effects on diverse properties, probably because of the reduced energy burden in terms of plasmid replication at high temperatures. The result suggests that plasmid curing is a simple and versatile approach for improving thermophiles. In particular, this approach may be effective for archaeal thermophiles because they grow at much higher temperatures and could have the greater energy burden on plasmid replication. Data mining has also shown that plasmids are distributed in archaeal thermophiles. This chapter provides a new tip for improving archaeal thermophiles, thereby increasing the opportunities for their use in various biotechnological applications

Srs2 and RecQ homologs cooperate in mei-3-mediated homologous recombination repair of Neurospora crassa

Homologous recombination and post-replication repair facilitate restart of stalled or collapsed replication forks. The SRS2 gene of Saccharomyces cerevisiae encodes a 3′–5′ DNA helicase that functions both in homologous recombination repair and in post-replication repair. This study identifies and characterizes the SRS2 homolog in Neurospora crassa, which we call mus-50. A knockout mutant of N.crassa, mus-50, is sensitive to several DNA-damaging agents and genetic analyses indicate that it is epistatic with mei-3 (RAD51 homolog), mus-11 (RAD52 homolog), mus-48 (RAD55 homolog) and mus-49 (RAD57 homolog), suggesting a role for mus-50 in homologous recombination repair. However, epistasis evidence has presented that MUS50 does not participate in post-replication repair in N.crassa. Also, the N.crassa mus-25 (RAD54 homolog) mus-50 double mutant is viable, which is in contrast to the lethal phenotype of the equivalent rad54 srs2 mutant in S.cerevisiae. Tetrad analysis revealed that mus-50 in combination with mutations in two RecQ homologs, qde-3 and recQ2, is lethal, and this lethality is suppressed by mutation in mei-3, mus-11 or mus-25. Evidence is also presented for the two independent pathways for recovery from camptothecin-induced replication fork arrest: one pathway is dependent on QDE3 and MUS50 and the other pathway is dependent on MUS25 and RECQ2

Fluctuation properties of strength function associated with the giant quadrupole resonance in 208Pb

We performed fluctuation analysis by means of the local scaling dimension for the strength function of the isoscalar (IS) giant quadrupole resonance (GQR) in 208Pb where the strength function is obtained by the shell model calculation including 1p1h and 2p2h configurations. It is found that at almost all energy scales, fluctuation of the strength function obeys the Gaussian orthogonal ensemble (GOE) random matrix theory limit. This is contrasted with the results for the GQR in 40Ca, where at the intermediate energy scale about 1.7 MeV a deviation from the GOE limit was detected. It is found that the physical origin for this different behavior of the local scaling dimension is ascribed to the difference in the properties of the damping process.Comment: 10 pages, 14 figures, submitted to Physical Review

Latencies of Reflex Discharges in Some Oro-facial Reflexes of the Frog

Unitary reflex discharges were recorded from the branches of the trigeminal nerve innervating the submental and masseter muscles following electrical stimulation of the lingual branch of the glossopharyngeal nerve, the maxillary branch of the trigeminal nerve and the mandibular branch of the facial nerve. Reflex discharges were effectively elicited by repetitive electrical stimulation of afferent nerves, but the number of reflex impulses as well as the latencies varied from discharge to discharge. This suggests that the pathway of these reflexes is polysynaptic

Resovist-Enhanced MRI for Preoperative Assessment of Colorectal Hepatic Metastases: A Case of Multiple Bile Duct Hamartomas Associated with Colon Cancer

Extensive preoperative assessment of hepatic metastases is required in colon cancer patients. We report a case in whom the preoperative investigation by ultrasound scan and contrast-enhanced computed tomography revealed numerous cystic lesions of the liver, suspicious of von Meyenburg complex. Magnetic resonance and magnetic resonance cholangiographic images demonstrated typical features of von Meyenburg complex. Further Resovist-enhanced magnetic resonance imaging detected two hemangiomas in addition to the multiple cystic lesions. So-called Kupffer cell imaging strongly helped the detection of these hemangiomas, and a combination of various magnetic resonance pulse sequences was of great value for the differential diagnosis of cystic lesions and hemangiomas. In cases in whom conventional imaging studies fail to give a definite diagnosis, such as in the present case, superparamagnetic iron oxide-enhanced magnetic resonance imaging is meaningful for adequate preoperative staging

Orbital- and spin-phase variability in the X-ray emission from the accreting pulsar Cen X-3

We analyzed 39 ks NuSTAR observation data of the high mass X-ray binary Cen X-3 in order to investigate the orbital- and spin-phase spectral variability. The observation covers the orbital phase of $\Phi=0.199$-$0.414$ of the source, where $\Phi=0$ corresponds to the mid-eclipse. The orbital-phase-resolved spectroscopy revealed that low energy photons are more dominant for the spectral fluctuation, and a large part of the variability can be explained in terms of absorption by clumps of stellar wind. The spin-phase-resolved spectroscopy together with energy-resolved pulse profiles, on the other hand, presented large flux variations in high energy bands, which suggests that the origin of the variability is the different efficiency of Comptonization inside the accretion column. The energy band which includes Fe emission lines or cyclotron resonance scattering feature (CRSF) shows distinct variability compared to the nearby bands. The Fe lines show low variability along the spin phase, which indicates that the emission regions are apart from the neutron star. The central energy and strength of the CRSF are both positively correlated with the spin-phase-resolved flux, which suggests that the emitted photons face stronger magnetic fields and deeper absorption when they come from high-flux regions. We also examined the independence of the orbital- and spin-phase variability. They showed no correlation with each other and were highly independent, which implies the accretion stream is stable during the observation.Comment: 20 pages, 12 figures, accepted for publication in Ap