19,009 research outputs found
Low-speed aerodynamic characteristics of a 0.08-scale YF-17 airplane model at high angles of attack and sideslip
Data were obtained with and without the nose boom and with several strake configurations; also, data were obtained for various control surface deflections. Analysis of the results revealed that selected strake configurations adequately provided low Reynolds number simulation of the high Reynolds number characteristics. The addition of the boom in general tended to reduce the Reynolds number effects
Simple threshold rules solve explore/exploit tradeāoffs in a resource accumulation search task
How, and how well, do people switch between exploration and exploitation to search for and accumulate resources? We study the decision processes underlying such exploration/exploitation tradeāoffs using a novel card selection task that captures the common situation of searching among multiple resources (e.g., jobs) that can be exploited without depleting. With experience, participants learn to switch appropriately between exploration and exploitation and approach optimal performance. We model participants' behavior on this task with random, threshold, and sampling strategies, and find that a linear decreasing threshold rule best fits participants' results. Further evidence that participants use decreasing thresholdābased strategies comes from reaction time differences between exploration and exploitation; however, participants themselves report nonādecreasing thresholds. Decreasing threshold strategies that āfrontāloadā exploration and switch quickly to exploitation are particularly effective in resource accumulation tasks, in contrast to optimal stopping problems like the Secretary Problem requiring longer exploration
Robust Bayesian detection of unmodelled bursts
A Bayesian treatment of the problem of detecting an unmodelled gravitational
wave burst with a global network of gravitational wave observatories reveals
that several previously proposed statistics have implicit biases that render
them sub-optimal for realistic signal populations.Comment: 9 pages, 1 figure, submitted to CQG Amaldi proceedings special issu
Postsynaptic Ī±1-Adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition
BACKGROUND: Syncope is a sudden transient loss of consciousness and postural tone with spontaneous recovery; the most common form is vasovagal syncope (VVS). During VVS, gravitational pooling excessively reduces central blood volume and cardiac output. In VVS, as in hemorrhage, impaired adrenergic vasoconstriction and venoconstriction result in hypotension. We hypothesized that impaired adrenergic responsiveness because of excess nitric oxide can be reversed by reducing nitric oxide. METHODS AND RESULTS: We recorded cardiopulmonary dynamics in supine syncope patients and healthy volunteers (aged 15-27 years) challenged with a dose-response using the Ī±1-agonist phenylephrine (PE), with and without the nitric oxide synthase inhibitor N(G)-monomethyl-L-arginine, monoacetate salt (L-NMMA). Systolic and diastolic pressures among control and VVS were the same, although they increased after L-NMMA and saline+PE (volume and pressor control for L-NMMA). Heart rate was significantly reduced by L-NMMA (P<0.05) for control and VVS compared with baseline, but there was no significant difference in heart rate between L-NMMA and saline+PE. Cardiac output and splanchnic blood flow were reduced by L-NMMA for control and VVS (P<0.05) compared with baseline, while total peripheral resistance increased (P<0.05). PE dose-response for splanchnic flow and resistance were blunted for VVS compared with control after saline+PE, but enhanced after L-NMMA (P<0.001). Postsynaptic Ī±1-adrenergic vasoconstrictive impairment was greatest in the splanchnic vasculature, and splanchnic blood flow was unaffected by PE. Forearm and calf Ī±1-adrenergic vasoconstriction were unimpaired in VVS and unaffected by L-NMMA. CONCLUSIONS: Impaired postsynaptic Ī±1-adrenergic vasoconstriction in young adults with VVS can be corrected by nitric oxide synthase inhibition, demonstrated with our use of L-NMMA
Impacts of a professional practice doctorate: a collaborative enquiry
Doctoral education aims to benefit those who undertake it, but does it exert a wider influence? Professional doctorates are commonly designed to have an impact beyond the individual concerned, but is this influence realised? This paper focuses on a collaborative enquiry by a group of academics and doctoral alumni from non-discipline-specific professional doctorates. The enquiry examined how the professional practice of the graduates changed as a result of their studies and what influence this had on their work and their profession. It found that there was considerable impact on the wider context of the alumni, but that these effects were due more to the capacity-building effect of the doctorate than on the particular outcomes of the study undertaken.
Key words: doctoral education, research impact, collaborative enquiry, professional practic
ContextVP: Fully Context-Aware Video Prediction
Video prediction models based on convolutional networks, recurrent networks,
and their combinations often result in blurry predictions. We identify an
important contributing factor for imprecise predictions that has not been
studied adequately in the literature: blind spots, i.e., lack of access to all
relevant past information for accurately predicting the future. To address this
issue, we introduce a fully context-aware architecture that captures the entire
available past context for each pixel using Parallel Multi-Dimensional LSTM
units and aggregates it using blending units. Our model outperforms a strong
baseline network of 20 recurrent convolutional layers and yields
state-of-the-art performance for next step prediction on three challenging
real-world video datasets: Human 3.6M, Caltech Pedestrian, and UCF-101.
Moreover, it does so with fewer parameters than several recently proposed
models, and does not rely on deep convolutional networks, multi-scale
architectures, separation of background and foreground modeling, motion flow
learning, or adversarial training. These results highlight that full awareness
of past context is of crucial importance for video prediction.Comment: 19 pages. ECCV 2018 oral presentation. Project webpage is at
https://wonmin-byeon.github.io/publication/2018-ecc
Review of the Laguerre-Gauss mode technology research program at Birmingham
Gravitational wave detectors from the advanced generation onwards are
expected to be limited in sensitivity by thermal noise of the optics, making
the reduction of this noise a key factor in the success of such detectors. A
proposed method for reducing the impact of this noise is to use higher-order
Laguerre-Gauss (LG) modes for the readout beam, as opposed to the currently
used fundamental mode. We present here a synopsis of the research program
undertaken by the University of Birmingham into the suitability of LG mode
technology for future gravitational wave detectors. This will cover our
previous and current work on this topic, from initial simulations and table-top
LG mode experiments up to implementation in a prototype scale suspended cavity
and high-power laser bench
Validity and practical utility of accelerometry for the measurement of in-hand physical activity in horses
Background:
Accelerometers are valid, practical and reliable tools for the measurement of habitual physical activity (PA). Quantification of PA in horses is desirable for use in research and clinical settings. The objective of this study was to evaluate a triaxial accelerometer for objective measurement of PA in the horse by assessment of their practical utility and validity.
Horses were recruited to establish both the optimal site of accelerometer attachment and questionnaire designed to explore owner acceptance. Validity and cut-off values were obtained by assessing PA at various gaits. Validation study- 20 horses wore the accelerometer while being filmed for 10Ā min each of rest, walking and trotting and 5 mins of canter work. Practical utility study- five horses wore accelerometers on polls and withers for 18Ā h; compliance and relative data losses were quantified.
Results:
Accelerometry output differed significantly between the four PA levels (Pā<0ā¢001) for both wither and poll placement. For withers placement, ROC analyses found optimal sensitivity and specificity at a cut-off of <47 counts per minute (cpm) for rest (sensitivity 99.5Ā %, specificity 100Ā %), 967ā2424Ā cpm for trotting (sensitivity 96.7Ā %, specificity 100Ā %) and ≥2425Ā cpm for cantering (sensitivity 96.0Ā %, specificity 97.0Ā %). Attachment at the poll resulted in optimal sensitivity and specificity at a cut-off of <707 counts per minute (cpm) for rest (sensitivity 97.5Ā %, specificity 99.6Ā %), 1546ā2609Ā cpm for trotting (sensitivity 90.33Ā %, specificity 79.25Ā %) and ≥2610Ā cpm for cantering (sensitivity 100Ā %, specificity 100Ā %) In terms of practical utility, accelerometry was well tolerated and owner acceptance high.
Conclusion:
Accelerometry data correlated well with varying levels of in-hand equine activity. The use of accelerometers is a valid method for objective measurement of controlled PA in the horse
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