Study of Marine Natural Products as Anti-SARS-CoV-2 Agents Using Molecular Modeling

Corresponding author (BioMolecular Sciences): Priyanka Samanta, [email protected]://egrove.olemiss.edu/pharm_annual_posters_2022/1018/thumbnail.jp

Influence of Silver Incorporation on the Structural and Electrical Properties of Diamond-Like Carbon Thin Films

A simple approach is proposed for obtaining low threshold field electron emission from large area diamond-like carbon (DLC) thin films by sandwiching either Ag dots or a thin Ag layer between DLC and nitrogen-containing DLC films. The introduction of silver and nitrogen is found to reduce the threshold field for emission to under 6 V/μm representing a near 46% reduction when compared with unmodified films. The reduction in the threshold field is correlated with the morphology, microstructure, interface, and bonding environment of the films. We find modifications to the structure of the DLC films through promotion of metal-induced sp bonding and the introduction of surface asperities, which significantly reduce the value of the threshold field. This can lead to the next-generation, large-area simple and inexpensive field emission devices. © 2013 American Chemical Society

A conceptual framework for the adoption of big data analytics by e-commerce startups: a case-based approach

E-commerce start-ups have ventured into emerging economies and are growing at a significantly faster pace. Big data has acted like a catalyst in their growth story. Big data analytics (BDA) has attracted e-commerce firms to invest in the tools and gain cutting edge over their competitors. The process of adoption of these BDA tools by e-commerce start-ups has been an area of interest as successful adoption would lead to better results. The present study aims to develop an interpretive structural model (ISM) which would act as a framework for efficient implementation of BDA. The study uses hybrid multi criteria decision making processes to develop the framework and test the same using a real-life case study. Systematic review of literature and discussion with experts resulted in exploring 11 enablers of adoption of BDA tools. Primary data collection was done from industry experts to develop an ISM framework and fuzzy MICMAC analysis is used to categorize the enablers of the adoption process. The framework is then tested by using a case study. Thematic clustering is performed to develop a simple ISM framework followed by fuzzy analytical network process (ANP) to discuss the association and ranking of enablers. The results indicate that access to relevant data forms the base of the framework and would act as the strongest enabler in the adoption process while the company rates technical skillset of employees as the most important enabler. It was also found that there is a positive correlation between the ranking of enablers emerging out of ISM and ANP. The framework helps in simplifying the strategies any e-commerce company would follow to adopt BDA in future. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature

Strange hardness characteristic of hydrogenated diamond-like carbon thin film by plasma enhanced chemical vapor deposition process

By creating nanostructures and controlling the hydrogen content and sp(3)/sp(2) bonding ratio, we report the formation of very hard (35.8 GPa) hydrogenated diamond-like carbon film at a self-bias of -100V using simple radio frequency-plasma enhanced chemical vapor deposition process. When the self-bias is varied and modifications such as incorporation of nitrogen and Ag interlayer are executed, the mechanical properties of such films, however, got altered that are correlated well with the structural changes investigated using various spectroscopic and microscopic techniques

Role of base pressure on the structural and nano-mechanical properties of metal/diamond-like carbon bilayers

The influence of base pressure on the structural and nano-mechanical properties of plasma produced metal (Cu and Ti)/diamond-like carbon (DLC) bilayers is reported. All of these samples show the formation of micro and nano-structured morphology with very low average roughness (less than 1 nm). The Cu/DLC and Ti/DLC bilayers deposited at low base pressure exhibit comparatively higher hardness and better nano-mechanical properties than the ones grown at higher base pressure. Highest hardness as similar to 49 GPa is obtained in Ti/DLC bilayer grown at low base pressure condition. Several other nano-mechanical parameters are also examined and correlated with each other. Present investigation will be useful to understand the role of base pressure on the properties of DLC coatings and may enhance its industrial application in term of hard and protective coatings

Photoluminescence and electrical conductivity of silicon containing multilayer structures of diamond like carbon

Photoluminescence and electrical conductivity of silicon containing multilayer structures of diamond like carbon were studied. These multilayer structures were deposited in a sequence a-Si:H/ Si-(a-C:H)/ a-C:H using conventional RF-PECVD technique. It was found that with the variation of silane partial pressure during the growth of middle layer (Si-(a-C:H)), the optical, electrical and photoluminescence properties of these multilayer structure varied. Electrical conductivity showed negative thermally activated process in these multilayer structure which disappeared after annealing the samples at 250 degrees C. The role of a-C:H as protective layer for luminescent Si-(a-C:H) layer has also been emphasized

Electrical transport in metal-carbon hybrid multijunction devices

Understanding the factors that influence the structural, mechanical and electrical properties of hybrid metal-carbon multilayer materials and devices are explored in this study by examining the effects of the choice of metal, Cu or Ti, and the number of metal-carbon bilayers. With up to four bilayers, corresponding to ten discrete metal-carbon electrical junctions, lower interfacial stresses and lower electrical resistance are always found in Cu multilayer structures, when compared with Ti containing multilayers. The lower electrical resistance is a result of a copper-carbon interaction which facilitates a carbon sp(3) to sp(2) bonding transformation and is accompanied by a metal-induced transformation of the carbon layer from an amorphous to nanostructured morphology which also aids in conduction. Time-of-flight secondary ion mass spectrometry measurements demonstrate that the two selected metals, Cu and Ti, represent extreme examples in their affinity to bond with carbon with Cu (Ti) representing a weak (strong) affinity metal for bonding. This study shows the importance of the metal-carbon interaction in understanding the mechanical stresses and electrical characteristics in particular, and the wider result of the role played by the relative chemical reactivity of the components in multijunction hybrid semiconductor-based devices in general

Field emission, morphological and mechanical properties of variety of diamond-like carbon thin films

The effect of nitrogen incorporation and sandwich titanium and copper layers, on field emission, morphological and mechanical properties of diamond-like carbon (DLC) thin films is explored. The introduction of foreign element (N2) and sandwich Cu and Ti layers changed the amorphous morphology to nanostructured, reduced the stress, enhanced the hardness (except N2 incorporated DLC film) and improved the field emission (except Ti/DLC bilayer) of modified DLC films. The associated versatile electrical and mechanical properties of modified DLC film made it a material of great utility in the development of field emission display panels and also lead to its application as a hard and protective coating on cutting tools, automobile parts etc. It is important to mention that DLC-based electronic materials may replace currently used soft electronic materials (such as Si) due to their enhanced stability under high energy radiation