Our water world : 4-H marine science discovery project : leader guide

This book is offered to youth leaders and teachers as a tool to help young learners discover some of the wonders that the sea has to offer. It is also a tool for youth development.Reprinted July 2001; original published July 1999. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalo

Exome sequencing of Finnish isolates enhances rare-variant association power.

Exome-sequencing studies have generally been underpowered to identify deleterious alleles with a large effect on complex traits as such alleles are mostly rare. Because the population of northern and eastern Finland has expanded considerably and in isolation following a series of bottlenecks, individuals of these populations have numerous deleterious alleles at a relatively high frequency. Here, using exome sequencing of nearly 20,000 individuals from these regions, we investigate the role of rare coding variants in clinically relevant quantitative cardiometabolic traits. Exome-wide association studies for 64 quantitative traits identified 26 newly associated deleterious alleles. Of these 26 alleles, 19 are either unique to or more than 20 times more frequent in Finnish individuals than in other Europeans and show geographical clustering comparable to Mendelian disease mutations that are characteristic of the Finnish population. We estimate that sequencing studies of populations without this unique history would require hundreds of thousands to millions of participants to achieve comparable association power

A guide to Oregon's commercial fishing vessels [1984]

Revised May 1984. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the Sea Grant Catalog: http://seagrant.oregonstate.edu/publication

Controlling weeds in alfalfa

Published October 1989. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalo

Genetic variation and gene expression across multiple tissues and developmental stages in a non-human primate

By analyzing multitissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate model. This catalog contains more genome-wide significant eQTLs per sample than comparable human resources and identifies sex- and age-related expression patterns. Findings include a master regulatory locus that likely has a role in immune function and a locus regulating hippocampal long noncoding RNAs (lncRNAs), whose expression correlates with hippocampal volume. This resource will facilitate genetic investigation of quantitative traits, including brain and behavioral phenotypes relevant to neuropsychiatric disorders

Monitoring root disease mortality : establishment report

Two thousand and thirty-nine trees on 213 plots are being monitored yearly for root disease infection and mortality. Three compartments on the Fernan Ranger District of the Idaho Panhandle National Forests are the site of the project. Relationships between factors such as species, aspect, slope, elevation, habitat type, stand appearance on aerial photography, plot root disease severity ratings, and measured volume losses due to root disease mortality are being evaluated. Effective means of judging past and future losses in root disease-affected stands are sought

'Prove me the bam!': victimization and agency in the lives of young women who commit violent offences

This article reviews the evidence regarding young women’s involvement in violent crime and, drawing on recent research carried out in HMPYOI Cornton Vale in Scotland, provides an overview of the characteristics, needs and deeds of young women sentenced to imprisonment for violent offending. Through the use of direct quotations, the article suggests that young women’s anger and aggression is often related to their experiences of family violence and abuse, and the acquisition of a negative worldview in which other people are considered as being 'out to get you' or ready to 'put one over on you'. The young women survived in these circumstances, not by adopting discourses that cast them as exploited victims, but by drawing on (sub)cultural norms and values which promote pre-emptive violence and the defence of respect. The implications of these findings for those who work with such young women are also discussed

Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates.

Current evidence from case/control studies indicates that genetic risk for psychiatric disorders derives primarily from numerous common variants, each with a small phenotypic impact. The literature describing apparent segregation of bipolar disorder (BP) in numerous multigenerational pedigrees suggests that, in such families, large-effect inherited variants might play a greater role. To identify roles of rare and common variants on BP, we conducted genetic analyses in 26 Colombia and Costa Rica pedigrees ascertained for bipolar disorder 1 (BP1), the most severe and heritable form of BP. In these pedigrees, we performed microarray SNP genotyping of 838 individuals and high-coverage whole-genome sequencing of 449 individuals. We compared polygenic risk scores (PRS), estimated using the latest BP1 genome-wide association study (GWAS) summary statistics, between BP1 individuals and related controls. We also evaluated whether BP1 individuals had a higher burden of rare deleterious single-nucleotide variants (SNVs) and rare copy number variants (CNVs) in a set of genes related to BP1. We found that compared with unaffected relatives, BP1 individuals had higher PRS estimated from BP1 GWAS statistics (P = 0.001 ~ 0.007) and displayed modest increase in burdens of rare deleterious SNVs (P = 0.047) and rare CNVs (P = 0.002 ~ 0.033) in genes related to BP1. We did not observe rare variants segregating in the pedigrees. These results suggest that small-to-moderate effect rare and common variants are more likely to contribute to BP1 risk in these extended pedigrees than a few large-effect rare variants

Got a stream? Grow plants!

Whether you have 1 or 500 acres, it's important to have natural vegetation growing along the streams on your property. It's good for wildlife, stream health and property values.Published October 2014. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalogKeywords: small ranch, riparian, vegetation, small farm, Streams, livestoc

An assessment of chloride-associated, and other roadside tree damage, on the Selway Road, Nez Perce National Forest

Tree damage following dust abatement/road stabilization treatment was evaluated on 12.5 miles of the Selway River Road, Nez Perce National Forest. Calcium chloride was applied in June of 2000, mostly at a rate of 51b/yd2 (18,600 lb./acre) or 6.9 lb/yd 2 (25,700 lb/acre). 1,189 trees up to 30 feet from the road were examined in June 2001 and again in December 2001. Western redcedar and Douglas-fir were most damaged by the chloride. Ponderosa pine was the most tolerant of the tree species. Severity of damage was associated with tree species, proximity of trees to road, and CaCl2 application rates. Cedar foliage samples collected in November 2001 from symptomatic trees near treated road averaged nearly seven times more chloride ion concentration than the controls. Treated Douglas-fir averaged 50 times more and ponderosa pine average 30 times more than their respective controls. As of December 2001, 12% of cedars were dead and another 18% appear to be dying. Douglas-fir fared worse with 29% dead and 12% dying. Grand fir and ponderosa pine had only 6% and 4%, respectively, dead or dying