423 research outputs found
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Frio brine sequestration pilot in the Texas Gulf Coast
A field experiment to pioneer CO2 injection for sequestration in a brine-bearing sandstone-shale sequence in the Texas Gulf Coast, USA, is in the preinjection modeling and planning phase. Innovations in this experiment include (1) CO2 injection into high-volume highpermeability rocks that have storage capacity sufficient to impact greenhouse gas emissions, (2) injection into a setting lacking the complications introduced by hydrocarbons and perturbations resulting from production and secondary recovery, and (3) intensive pre-, syn-, and post-injection monitoring and modeling for validation of the effectiveness of sequestration. The experiment is designed to provide a rapid increase in information from a small-volume and short-duration injection.Bureau of Economic Geolog
Nineteenth century application of the Act of Division of Commonty, 1695, to the scattalds of Shetland
SIGLEAvailable from British Library Document Supply Centre- DSC:D42880/82 / BLDSC - British Library Document Supply CentreGBUnited Kingdo
Clients\u27 Internal Representations of Their Therapists
Thirteen adults in long-term individual psychotherapy were interviewed regarding their internal representations (defined as bringing to awareness the internalized image ) of their therapists. Results indicated that in the context of a good therapeutic relationship, clients\u27 internal representations combined auditory, visual, and kinesthetic (i.e., felt presence) modalities; were triggered when clients thought about past or future sessions, or when distressed; occurred in diverse locations; and varied in frequency, duration, and intensity. Clients felt positively about their representations and used them to introspect or influence therapy within sessions, beyond sessions, or both. The frequency of, comfort with, and use of clients\u27 internal representations increased over the course of therapy, and the representations benefited the therapy and therapeutic relationship. Therapists tended not to take a deliberate role in creating clients\u27 internal representations, and few clients discussed their internal representations with their therapists
Fluorescence Correlation Spectroscopy Reveals Efficient Cytosolic Delivery of Protein Cargo by Cell-Permeant Miniature Proteins.
New methods for delivering proteins into the cytosol of mammalian cells are being reported at a rapid pace. Differentiating between these methods in a quantitative manner is difficult, however, as most assays for evaluating cytosolic protein delivery are qualitative and indirect and thus often misleading. Here we make use of fluorescence correlation spectroscopy (FCS) to determine with precision and accuracy the relative efficiencies with which seven different previously reported "cell-penetrating peptides" (CPPs) transport a model protein cargo-the self-labeling enzyme SNAP-tag-beyond endosomal membranes and into the cytosol. Using FCS, we discovered that the miniature protein ZF5.3 is an exceptional vehicle for delivering SNAP-tag to the cytosol. When delivered by ZF5.3, SNAP-tag can achieve a cytosolic concentration as high as 250 nM, generally at least 2-fold and as much as 6-fold higher than any other CPP evaluated. Additionally, we show that ZF5.3 can be fused to a second enzyme cargo-the engineered peroxidase APEX2-and reliably delivers the active enzyme to the cell interior. As FCS allows one to realistically assess the relative merits of protein transduction domains, we anticipate that it will greatly accelerate the identification, evaluation, and optimization of strategies to deliver large, intact proteins to intracellular locales
Health policy and its unintended consequences for midwife-woman partnerships: is normal pregnancy at risk when the BMI measure is used?
Background: Little attention has been paid to understanding the unintended consequences of health policy for midwife-woman partnerships. The measure of Body Mass Index (BMI) is one such policy example which has become established in contemporary midwifery practice as a tool for assessing pregnancy risk. The universal acceptance of BMI creates an unsettling paradox for midwives concerned with promoting woman-centred practice. The increasing focus on BMI is challenging for midwives as they navigate ethical tensions when directed to undertake practices which have potential unwonted consequences for the midwife-woman partnership. Aim: The aim of the study was to explore the use of an indicator, using BMI as an example, to provide an international perspective on obesity prevention policy and maternity care provision. Method: A comparative case study approach was taken, using descriptive cross-national comparative analysis of obesity prevention policy, weight management guidelines and midwifery models of care in New Zealand and Scotland. Discussion: Despite promoting healthy weight gain in pregnancy, New Zealand and Scottish health policies may be missing health promotion opportunities. Focusing on BMI in maternity, per se, should not prohibit other assessment of lifestyle issues or delivery of services based on individual needs, capacities, histories and sociological characteristics. Relying solely on pre-pregnancy BMI as a marker of health in all women has remained relatively unchallenged and, as such, constitutes a policy problem because it occludes the factoring in of other lifestyle issues that may significantly alter individual risk status. Further, such an assessment of risk status is ideally arrived at within a partnership model of maternity care, rather than reliance on an a priori medical test. Conclusion: Decontextualised policies are challenging for midwives where medical and midwifery values are in conflict. Policy which fails to consider the multiple and complex contexts of women's lives is confronting for midwives as they attempt to re-articulate the meaning of woman-centred practice. Furthermore, BMI as a tool may be ineffectual. The current focus on BMI in policy and practice requires re-consideration
A Blinding Lack of Progress: Management Rhetoric and Affirmative Action
In this study we explore how versions of organizational reality and gender are constructed in management discourse and whether such patterns change over time. Specifically, we examine management explanations and accounts of the gendered nature of their organizations through their commentaries on their affirmative action programmes. In Australia private sector organizations with 100 or more employees are required to report to government on their affirmative action programmes for women. In these documents, management representatives outline objectives for the coming year and report on their progress in reducing employment-related barriers for women. In doing so they account for the 'problem' of gender-based discrimination that affirmative action is designed to address, justify their actions (or lack of action) and reproduce versions of gendered identity. Thus we use affirmative action reporting as cases of management rhetoric to explore how aspects of gender and organization are constructed, taken for granted, challenged or problematized. Comparing reports from the hospitality sector over a 14-year period, we explore whether there is any evidence of discursive change in management accounts of the gendered nature of their organizations
The Saving Power of Community Creativity: Highlights of Arts, Culture, and Creative Placemaking Responses to COVID-19
For several years, the Center for Community Progress (Community Progress) and Metris Arts Consulting have explored how arts and culture organizations are revitalizing communities that have been hit hard with vacancy and abandonment. In mid-2020, as we began to understand the pandemic's devastating health, economic, and social impacts on communities and the policy demands surrounding the calls for racial justice, we also began hearing how community-based organizations using arts and culture had shifted their work to provide critical community support. This resource highlights the efforts of creative leaders during the pandemic and also seeks to inspire others trying to address acute needs.
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Capacity investigation of brine-bearing sands of the Frio Formation for geologic sequestration of CO2
The capacity of fluvial brine-bearing formations to sequester CO2 is investigated using numerical simulations of CO2 injection and storage. Capacity is defined as the volume fraction of the subsurface available for CO2 storage and is conceptualized as a product of factors that account for two-phase flow and transport processes, formation geometry, formation heterogeneity, and formation porosity. The space and time domains used to define capacity must be chosen with care to obtain meaningful results, especially when comparing different authors’ work. Physical factors that impact capacity include permeability anisotropy and relative permeability to CO2, brine/CO2 density and viscosity ratios, the shape of the trapping structure, formation porosity and the presence of low permeability layering.National Energy Technology LaboratoryBureau of Economic Geolog
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