Characterization antibacterial constituent from Ficus deltoideus Jack leaves Karakterisasi konstituen antibakteri dari daun Ficus deltoideus Jack

An antibacterial constituent, has been isolated from Ficus deltoideus Jack leaves. Based on spectroscopic data (IR, lH-NMR, 13CNMRlD and 2D and MS), the structure of this compound was identified as Olean-12en-3&#946-ol, (&#946-amyrln), C&#8323&#8320H&#8325&#8320O. This compound showed antibacterial activities against E. coli, B. subtilis and S. aureus. The minimum inhibition concentration (MIC) agains E. coli, B. subtilis and S. aureus are 230, 380 and 460 (µ/mL) respectively. Suatu konstituen antibakteri, telah diisolasi dari daun Ficus deltoideus Jack. Karakterisasi struktur menggunakan data spektroskopi IR, lH-NMR, 13C_ NMR, lD dan 2D serta data MS, menunjukkan bahwa konstituen hasll isolasi adalah Olean-12en-3&#946-0I, (&#946-amyrin), C&#8323&#8320H&#8325&#8320O. Uji aktivitas antibakteri terhadap E. coli, B.subtilis dan S. aureus menunjukkan bahwa &#946-amyrin dapat menghambat pertumbuhan bakteri, dengan nllai MIC 230 µ/mL untuk E. coli, 380 µ/mLuntuk B. subtilis, dan 460 µ/mL untuk bakteri S. aureus

Characterization antibacterial constituent from Ficus deltoideusJack leaves

An antibacterial constituent, has been isolated from Ficus deltoideus Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13 C NMR 1D and 2D and MS), the structure of this compound was identified as Olean-12en-3β-ol, (β-amyrin), C30H50O. This compound showed antibacterial activities against E. coli, B. subtilis and S.  aureus.  The minimum inhibition concentration (MIC) agains  E.  coli,  B. subtilisand  S. aureusare 230, 380 and 460 (µg/mL) respectively.Key words: Antibacterial activity,Ficus deltoideusJack, β-amyri

STRUCTURE ELUCIDATION OF ANTIBACTERIAL COMPOUND FROM <i>Ficus deltoidea</i> Jack LEAVES

An antibacterial compound has been isolated from Ficus deltoidea Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13C NMR 1D and 2D and MS), the structure of this compound was identified as 3β-hydroksilup-20(29)-en, (lupeol), C30H50O. This compound showed antibacterial activities against E. coli, B. subtilis and S. aureus. The minimum inhibition concentration (MIC) against E. coli, B. subtilis and S. aureus are 150, 220 and 130 μg/mL respectively

PROFIL FITOKIMIA DAN AKTIFITAS ANTIACETYLCHOLINESTERASE DARI DAUN TABAT BARITO (Ficus Deltoidea Jack)

Phytochemical study and antiacetylcholinesterase assay by using bioautography method were carried out on polar fraction of tabat barito (Ficus deltoidea jack) leaves. The result of this studies showed that the leaves contained flavonoid, terpenoid, steroid and fenolic compounds. This extract gave positive result on antiacetylcholinesterase. Keywords: Antiacetylcholinesterase, Ficus deltoidea Jac