Imputation of Repeatedly-observed Multinomial Variables in Longitudinal Surveys

It is now a standard practice to replace missing data in longitudinal surveys with imputed values, but there is still much uncertainty about the best approach to adopt. Using data from a real survey, we compared different strategies combining multiple imputation and the chained equations method, the two main objectives being 1) to explore the impact of the explanatory variables in the chained regression equations, 2) to study the effect of imputation on causality between successive waves of the survey. Results were very stable from one simulation to another, and no systematic bias did appear. The critical points of the method lied in the proper choice of covariates and in the respect of the temporal relation between variables

Interruptions de grossesse dans le canton de Vaud en 2018 : l’essentiel

Les interruptions de grossesse pratiquées en Suisse doivent obligatoirement être annoncées au Médecin cantonal. Dans le canton de Vaud, des analyses approfondies sont menées sur les informations ainsi récoltées. Quelles sont les dernières données ? Quelles sont les caractéristiques des femmes ayant eu recours à ce type d'intervention en 2018 et quelles sont les caractéristiques de ces interventions

La prévention et le sexting : un état des lieux

Le développement social et relationnel des adolescent-e-s et des jeunes adultes s’effectue aujourd’hui avec celui d’Internet et des nouvelles technologies. Dans ce contexte, les interactions et la transmission d’informations numériques sont facilitées et peu restreintes, ce qui peut mener à un certain nombre d’enjeux en termes d’usage des technologies et de gestion de l’image numérique. Le sexting fait partie de ces problématiques. Cette pratique pouvant, de manière générale, se définir comme l’échange électronique de matériel personnel à caractère sexuel ou intime, peut parfois mener à des situations dramatiques lorsque, par exemple, le contenu d’un message est transféré sans consentement à d’autres personnes. Après avoir mené une première recherche exploratoire qualitative sur la pratique du sexting chez les jeunes, la thématique de la prévention relative au sexting s’est avérée particulièrement intéressante à approfondir. En effet, très peu de jeunes ont rapporté se rappeler de messages ou campagnes de prévention autour du sexting spécifiquement. Au vu de ces résultats, nous avons considéré qu’il était essentiel d’établir un état des lieux de l’offre préventive sur la thématique du sexting, plus particulièrement dans le canton de Vaud, afin de vérifier les dires de certains jeunes sur le manque d’intervention et de discussion sur le sexting et ses possibles dérives. A travers cet état des lieux et ce rapport, nous proposons donc un catalogue permettant de répertorier et d’offrir une vue d’ensemble des différents acteurs-trices et ressources à disposition dans le cadre de la prévention relative à la pratique du sexting auprès des jeunes

GenerationFRee : Rapport final de l’étude longitudinale sur la problématique des jeux d’argent chez les jeunes (15-24 ans) du canton de Fribourg.

Ce rapport concerne l’étude longitudinale appelée GenerationFRee qui s’est tenue de l’année scolaire 2014-2015 à l’année scolaire 2018-2019 dans le canton de Fribourg, soit 5 années de récolte de données. Dans ce rapport, nous focalisons surtout sur l’évolution des pratiques quant aux jeux d’argent et à l’endettement, mais nous présentons les données longitudinales sur plusieurs thématiques telles que la consommation de substance et les comportements à risque. En plus de ces données, nous avons également organisé un groupe focus (groupe de discussion) avec une dizaine de jeunes qui n’ont pas participé à l’étude pour récolter leur opinion sur nos résultats. Dans le cadre de cette étude, nous avons utilisé le South Oaks Gambling Screen – Revised for Adolescents (SOGS-RA), un instrument pour détecter le jeu excessif parmi les jeunes. Les répondants étaient répartis entre non joueurs (pas joué au cours des 12 derniers mois), joueurs non problématiques (score du SOGS de 0 à 1 pour les 12 questions), joueurs à risque (score de 2 ou 3) et joueurs problématiques (score de 4 ou plus)

Sexuality of Young Adults with Cerebral Palsy: Experienced Limitations and Needs

Objective of this study is to describe the problems young adults with Cerebral Palsy (CP) experience in the various stages of the sexual response cycle, and the physical and emotional obstacles they experience with sexuality. In this prospective cohort study 74 young adults (46 men; 28 women) with CP and average intelligence participated, aged 20–24 years. Twenty percent of these young adults with CP experienced anorgasmia, 80% reported physical problems with sex related to CP and 45% emotional inhibition to initiate sexual contact. In 90% of the participants, sexuality had not been discussed during the rehabilitation treatment. Many adolescents reported wanting information about the impact of CP on sexuality and reproduction (35%), about interventions (26%), tools and medicines (16%) and about problems with their partner (14%). Young adults with CP can experience various problems or challenges with sexuality. For preventing sexual difficulties and treating sexual problems, health care professionals need to proactively take the initiative to inform young people with CP about sexuality

Association between substance use and psychosocial characteristics among adolescents of the Seychelles

BACKGROUND: We examined the associations between substance use (cigarette smoking, alcohol drinking, and cannabis use) and psychosocial characteristics at the individual and family levels among adolescents of the Seychelles, a rapidly developing small island state in the African region. METHODS: A school survey was conducted in a representative sample of 1432 students aged 11-17 years from all secondary schools. Data came from a self-administered anonymous questionnaire conducted along a standard methodology (Global School-based Health Survey, GSHS). Risk behaviors and psychosocial characteristics were dichotomized. Association analyses were adjusted for a possible classroom effect. RESULTS: The prevalence of cigarette smoking, alcohol drinking and cannabis use was higher in boys than in girls and increased with age. Age-adjusted and multivariate analyses showed that several individual level characteristics (e.g. suicidal ideation and truancy) and family level characteristics (e.g. poor parental monitoring) were associated with substance use among students. CONCLUSIONS: Our results suggest that health promotion programs should simultaneously address multiple risk behaviors and take into account a wide range of psychosocial characteristics of the students at the individual and family levels

Early Trauma and Increased Risk for Physical Aggression during Adulthood: The Moderating Role of MAOA Genotype

Previous research has reported that a functional polymorphism in the monoamine oxidase A (MAOA) gene promoter can moderate the association between early life adversity and increased risk for violence and antisocial behavior. In this study of a combined population of psychiatric outpatients and healthy volunteers (N = 235), we tested the hypothesis that MAOA genotype moderates the association between early traumatic life events (ETLE) experienced during the first 15 years of life and the display of physical aggression during adulthood, as assessed by the Aggression Questionnaire. An ANOVA model including gender, exposure to early trauma, and MAOA genotype as between-subjects factors showed significant MAOA×ETLE (F1,227 = 8.20, P = 0.005) and gender×MAOA×ETLE (F1,227 = 7.04, P = 0.009) interaction effects. Physical aggression scores were higher in men who had experienced early traumatic life events and who carried the low MAOA activity allele (MAOA-L). We repeated the analysis in the subgroup of healthy volunteers (N = 145) to exclude that the observed G×E interactions were due to the inclusion of psychiatric patients in our sample and were not generalizable to the population at large. The results for the subgroup of healthy volunteers were identical to those for the entire sample. The cumulative variance in the physical aggression score explained by the ANOVA effects involving the MAOA polymorphism was 6.6% in the entire sample and 12.1% in the sub-sample of healthy volunteers. Our results support the hypothesis that, when combined with exposure to early traumatic life events, low MAOA activity is a significant risk factor for aggressive behavior during adulthood and suggest that the use of dimensional measures focusing on behavioral aspects of aggression may increase the likelihood of detecting significant gene-by-environment interactions in studies of MAOA-related aggression

Support for e-cigarette regulations among Australian young adults

Background: Surveying support for various regulatory options relating to e-cigarettes can assist policymakers to identify those that have broad support and are therefore likely to be easier to implement. However, data on support for potential e-cigarette regulations in Australia are limited. To inform regulatory efforts, the present study assessed attitudes to the regulation of e-cigarettes among Australian young adults, the most prevalent users of e-cigarettes and therefore the most likely population segment to be affected by e-cigarette regulations. Methods: A total of 1116 Australians aged 18 to 25 years (59% female) completed an online survey where they were presented with various statements relating to the regulation of e-cigarettes and asked to report on the extent to which they agreed or disagreed with each. Statements presented either a restrictive or non-restrictive approach to e-cigarette regulation. Results: Across all statements, 10-22% of respondents responded "don't know" while 23-35% neither agreed nor disagreed, indicating general ambivalence. There was a moderate level of support (33-37%) for regulating e-cigarette sales/use and treating e-cigarettes like tobacco products. Only 20% of respondents were in favour of allowing the use of e-cigarettes in smoke-free areas. Smokers, e-cigarette users, and those who did not believe in the harms associated with e-cigarettes were typically less likely than other respondents to support restrictive approaches. Conclusions: The young Australian adults surveyed were somewhat supportive of restrictions around the sale and use of e-cigarettes, but generally opposed outright bans and any need for a prescription from a medical practitioner. Increasing awareness of the harms associated with the use of e-cigarettes represents a potential strategy to gaining regulatory support

Self-reported health experiences of children living with congenital heart defects: Including patient-reported outcomes in a national cohort study

Background: Understanding children’s views about living with congenital heart defects (CHDs) is fundamental to supporting their successful participation in daily life, school and peer relationships. As an adjunct to a health and quality of life outcomes questionnaire, we asked school-age children who survived infant heart procedures to describe their experiences of living with CHDs. Methods: In a UK-wide cohort study, children aged 10 to 14 years with CHDs self-completed postal questionnaires that included an open question about having a ‘heart problem’. We compared the characteristics of children with more and less severe cardiac diagnoses and, through collaborative inductive content analysis, investigated the subjective experiences and coping strategies described by children in both clinical severity groups. Results: Text and/or drawings were returned by 436 children (246 boys [56%], mean age 12.1 years [SD 1.0; range 10–14]); 313 had less severe (LS) and 123 more severe (MS) cardiac diagnoses. At the most recent hospital visit, a higher proportion of the MS group were underweight (more than two standard deviations below the mean for age) or cyanosed (underweight: MS 20.0%, LS 9.9%; cyanosed: MS 26.2%, LS 3.5%). Children in the MS group described concerns about social isolation and feeling ‘different’, whereas children with less severe diagnoses often characterised their CHD as ‘not a big thing’. Some coping strategies were common to both severity groups, including managing health information to avoid social exclusion, however only children in the LS group considered their CHD ‘in the past’ or experienced a sense of survivorship. Conclusions: Children’s reported experiences were not dependent on their cardiac diagnosis, although there were clear qualitative differences by clinical severity group. Children’s concerns emphasised social participation and our findings imply a need to shift the clinical focus from monitoring cardiac function to optimising participation. We highlight the potential for informing and evaluating clinical practice and service provision through seeking patient-reported outcomes in paediatric care