Target Acceleration Estimation from Radar Position Data using Neural Network

This work is a preliminary investigation on target manoeuvre estimation in real-time from the available measurements of noisy position data from tracking radar using an artificial neural network (ANN). Recently, simulation study of target manoeuvre estimation in real-time from the same position alone measurement using extended Kalman filter has been carried out in a simulated environment using measurements at 100 ms interval. The results reveal that the estimated acceleration consists of substantial error and lag, which is a stumbling block for guidance accuracy in real-time. So, the target acceleration has been estimated using the ANN with less error and lag than the same using Kalman estimator

Target Acceleration Estimation from Radar Position Data using Neural Network

This work is a preliminary investigation on target manoeuvre estimation in real-time from the available measurements of noisy position data from tracking radar using an artificial neural network (ANN). Recently, simulation study of target manoeuvre estimation in real-time from the same position alone measurement using extended Kalman filter has been carried out in a simulated environment using measurements at 100 ms interval. The results reveal that the estimated acceleration consists of substantial error and lag, which is a stumbling block for guidance accuracy in real-time. So, the target acceleration has been estimated using the ANN with less error and lag than the same using Kalman estimator

Effect of dietary nanosilver on gut proteases and general performance in Zebrafish (Danio rerio)

The present study was conducted to evaluate the effect of dietary inclusion of silver nanoparticle on general performance and digestive proteases in zebra fish. Four experimental diets were designed with a concentration of 5, 20 and 40 parts per billion (ppb) nanoparticles in the diet (named S5, S20, and S40, respectively) and control group without any nanoparticles (S0). There was no significant difference was observed in FI and FCR between the dietary treatments. At the end of the experiment, S20 exhibited highest WG and SGR followed by S40 compared with other treatments while, there was no significant difference observed between S0 and S5. Similar trends were also observed in total protease enzyme activity. To evaluate the protease enzyme patterns on gut extract, substrate SDS-PAGE was performed and the inhibition of zymogram was studied. The results showed that there was no difference in banding patterns between S0 and S5 with EDTA treated samples whereas two extra bands of molecular weight (MW) 67 and 37 appeared in S20 and S40, were inhibited by EDTA indicating the presence of metalloprotease in those dietary regimes. There were no differences in the banding patterns of PMSF treated samples suggesting that the total serine protease remains unaffected by the dietary regimes. To conclude, we found 20 ppb inclusion of silver nanoparticle in fish diet improves general performance and induces metalloprotease activity in fish. Further detailed study is required before establishing dietary inclusion of silver nanoparticle for industrial purposes

Cancer Stem Cells in Recurrent and Drug-Resistant Lung Cancers

With a 5-year survival rate of less than 20%, lung cancer is a leading cause of cancer-related deaths worldwide. Considering the treatments currently in place, this statistic is frankly shocking. A possible explanation for the disconnect between sophisticated treatments and the survival rate can be found in the Cancer Stem Cell (CSC) hypothesis. The CSC hypothesis suggests the idea of a subpopulation of tumor cells with the abilities of self-renewal, cancer initiation, and further maintenance of tumors. Lung CSCs have been associated with resistance to radiation and chemotherapeutic treatments. CSCs have also been implicated in recurrent cancers; if the CSCs are not completely killed off after treatment, the cancer tends to reemerge. Extensive investigation of CSCs to determine their responsibility in recurrent and drug-resistant cancers heavily relied on the use of specific markers present in CSCs, including CD133, ALDH, ABCG2, and Nanog. Yet another method that results in increased resistance to treatment is epithelial mesenchymal transition, or EMT. Through this process, epithelial cells lose the epithelial phenotype and gain mesenchymal properties. One of these properties is increased drug- resistance, rendering EMT culpable – at least in part – for drug-resistance in cancer cells . Furthermore, since miRNA-based therapies are coming to light, various miRNAs will be discussed in terms of their relationship to chemoresistance as well as CSCs in general. Finally, a discussion of the natural and synthetic anti-cancer compounds curcumin, CDF, and BR-DIM will ensue

Fast Actively Secure OT Extension for Short Secrets

Oblivious Transfer (OT) is one of the most fundamental cryptographic primitives with wide-spread application in general secure multi-party computation (MPC) as well as in a number of tailored and special-purpose problems of interest such as private set intersection (PSI), private information retrieval (PIR), contract signing to name a few. Often the instantiations of OT require prohibitive communication and computation complexity. OT extension protocols are introduced to compute a very large number of OTs referred as extended OTs at the cost of a small number of OTs referred as seed OTs. We present a fast OT extension protocol for small secrets in active setting. Our protocol when used to produce $1$-out-of-$n$ OTs outperforms all the known actively secure OT extensions. Our protocol is built on the semi-honest secure extension protocol of Kolesnikov and Kumaresan of CRYPTO\u2713 (referred as KK13 protocol henceforth) which is the best known OT extension for short secrets. At the heart of our protocol lies an efficient consistency checking mechanism that relies on the linearity of Walsh-Hadamard (WH) codes. Asymptotically, our protocol adds a communication overhead of $O(\mu \log{\kappa})$ bits over KK13 protocol irrespective of the number of extended OTs, where $\kappa$ and $\mu$ refer to computational and statistical security parameter respectively. Concretely, our protocol when used to generate a large enough number of OTs adds only $0.011-0.028\%$ communication overhead and $4-6\%$ runtime overhead both in LAN and WAN over KK13 extension. The runtime overheads drop below $2\%$ when in addition the number of inputs of the sender in the extended OTs is large enough. As an application of our proposed extension protocol, we show that it can be used to obtain the most efficient PSI protocol secure against a malicious receiver and a semi-honest sender

A multiparametric approach for rejuvenation of the Gaurikund geothermal spring system in the Northwest Himalayan region

The Gaurikund town falls on the way of the famous trekking route to Kedarnath that faced the wrath of the 2013 flood disaster. This fateful event severed more than 5000 casualties, demolished several infrastructures, and shifted the course of Gaurikund spring from its original position. Nevertheless, the Gaurikund geothermal spring system located in the Himalayan Geothermal Belt of the Garhwal region is preeminent for religious beliefs, balneotherapeutic values and a gateway to delve within the geothermal and hydrological characteristics of the area. In this perspective, restoration of Gaurikund geothermal spring system becomes a necessity. A multiparametric approach comprising geospatial, geology, hydrochemistry and geophysics has been used to study and justify these aspects at Gaurikund. The geological studies infer that the geothermal spring gets recharged by the steep, southerly dipping joints in granite gneiss. Subsequently, the deep percolated water heats up due to the high geothermal gradient and then emerge along the Vaikrita Thrust and its sympathetic minor fault-thrust system by advection. Moreover, four spring outlets are inventoried, with discharge varying from 7.46 to 95.54 L/min. The normal emissivity model uses the pre and post-disaster satellite data and generates maximum kinetic temperature images, showing a positive correlation between land surface temperature and spring discharge. Two-dimensional Electrical Resistivity Tomography (Schlumberger, Wenner and Gradient configurations) survey revealed two low resistivity zones proximal to the geothermal spring on the right bank of the Mandakini river. The engineering interventions carried out by bank protection and construction of small gully plugs in the catchment area is recommended along Gaurikund-Sonprayag section on the right bank of Mandakini river

Disc Instantons in Linear Sigma Models

We construct a linear sigma model for open-strings ending on special Lagrangian cycles of a Calabi-Yau manifold. We illustrate the construction for the cases considered by Aganagic and Vafa in hep-th/0012041. This leads naturally to concrete models for the moduli space of open-string instantons. These instanton moduli spaces can be seen to be intimately related to certain auxiliary boundary toric varieties. By considering the relevant Gelfand-Kapranov-Zelevinsky (GKZ) differential equations of the boundary toric variety, we obtain the contributions to the worldvolume superpotential on the A-branes from open-string instantons. By using an ansatz due to Aganagic, Klemm and Vafa in hep-th/0105045, we obtain the relevant change of variables from the linear sigma model to the non-linear sigma model variables - the open-string mirror map. Using this mirror map, we obtain results in agreement with those of AV and AKV for the counting of holomorphic disc instantons.Comment: 1+32 pages, 1 figure, LaTeX2e; (v2) Tables and References added, typos fixe

Seasonal occurrence of anoxygenic photosynthesis in Tillari and Selaulim reservoirs, Western India

© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Biogeosciences 9 (2012): 2485-2495, doi:10.5194/bg-9-2485-2012.Phytoplankton and bacterial pigment compositions were determined by high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) in two freshwater reservoirs (Tillari Dam and Selaulim Dam), which are located at the foothills of the Western Ghats in India. These reservoirs experience anoxia in the hypolimnion during summer. Water samples were collected from both reservoirs during anoxic periods while one of them (Tillari Reservoir) was also sampled in winter, when convective mixing results in well-oxygenated conditions throughout the water column. During the period of anoxia (summer), bacteriochlorophyll (BChl) e isomers and isorenieratene, characteristic of brown sulfur bacteria, were dominant in the anoxic (sulfidic) layer of the Tillari Reservoir under low light intensities. The winter observations showed the dominance of small cells of Chlorophyll b-containing green algae and cyanobacteria, with minor presence of fucoxanthin-containing diatoms and peridinin-containing dinoflagellates. Using total BChl e concentration observed in June, the standing stock of brown sulfur bacteria carbon in the anoxic compartment of Tillari Reservoir was estimated to be 2.27 gC m−2, which is much higher than the similar estimate for carbon derived from oxygenic photosynthesis (0.82 gC m−2. The Selaulim Reservoir also displayed similar characteristics with the presence of BChl e isomers and isorenieratene in the anoxic hypolimnion during summer. Although sulfidic conditions prevailed in the water column below the thermocline, the occurrence of photo-autotrophic bacteria was restricted only to mid-depths (maximal concentration of BChl e isomers was detected at 0.2% of the surface incident light). This shows that the vertical distribution of photo-autotrophic sulfur bacteria is primarily controlled by light penetration in the water column where the presence of H2S provides a suitable biogeochemical environment for them to flourish.Financial support for this work was provided by the Council of Scientific & Industrial Research (CSIR) and Ministry of Earth Sciences (MoES). S. Kurian acknowledges POGO-SCOR for financial support to visit WHOI. R. Roy, G. Narvenkar and A. Sarkar received fellowship support from CSIR. D. Repeta acknowledges support from US National Science Foundation Center Award EF0424599 to the Center for Microbial Oceanography: Research and Education (C-MORE)