Effect of Mobile Phone Usage on Students during the Pandemics Covid-19

Our aim was to know the effect of mobile phone during lockdown among students A total number of 108 students completed the questionnaire The questions were asked related to mobile phone usage Students of secondary Higher secondary and higher education were the sample of the study Online survey was conducted finding of the study showed that all students in the study were using mobile phone majority of students were using their mobile phone more than before the lockdown During the pandemic they are spending more time on their mobile phone for different purposes like studies entertainment for gaming etc Result of the study also revealed that students are facing problem like eye irritation neck pain et

Driving calmodulin protein towards conformational shift by changing ionization states of selected residues

Proteins are complex systems made up of many conformational sub-states which are mainly determined by the folded structure. External factors such as solvent type, temperature, pH and ionic strength play a very important role in the conformations sampled by proteins. Here we study the conformational multiplicity of calmodulin (CaM) which is a protein that plays an important role in calcium signaling pathways in the eukaryotic cells. CaM can bind to a variety of other proteins or small organic compounds, and mediates different physiological processes by activating various enzymes. Binding of calcium ions and proteins or small organic molecules to CaM induces large conformational changes that are distinct to each interacting partner. In particular, we discuss the effect of pH variation on the conformations of CaM. By using the pKa values of the charged residues as a basis to assign protonation states, the conformational changes induced in CaM by reducing the pH are studied by molecular dynamics simulations. Our current view suggests that at high pH, barrier crossing to the compact form is prevented by repulsive electrostatic interactions between the two lobes. At reduced pH, not only is barrier crossing facilitated by protonation of residues, but also conformations which are on average more compact are attained. The latter are in accordance with the fluorescence resonance energy transfer experiment results of other workers. The key events leading to the conformational change from the open to the compact conformation are (i) formation of a salt bridge between the N-lobe and the linker, stabilizing their relative motions, (ii) bending of the C-lobe towards the N-lobe, leading to a lowering of the interaction energy between the two-lobes, (iii) formation of a hydrophobic patch between the two lobes, further stabilizing the bent conformation by reducing the entropic cost of the compact form, (iv) sharing of a Ca+2 ion between the two lobes

Assessment of the Time Management and Stress among Nursing Staff in Selected Wards of Tertiary Care Hospital, Chandigarh (2017- 2018): A Descriptive Study

Nursing by its nature is an occupation which is prone to high degree of stress level and busy schedule. This study was done to assess the time management and stress among nursing staff and to assess the correlation between time management and stress among nurses. This was a descriptive study conducted in the selected wards of tertiary care hospital (Psychiatry Ward, Advance Trauma Centre, Advance Eye Centre, Maternity Ward, Communicable Disease Ward, Advance Pediatrics Centre). Data was collected by using socio-demographic profile, Nurses Time management Inventory for Personal life, Nurses Time Management Inventory for Professional life, Nursing Stress Inventory. The data was analyzed using SPSS (Version 20.0). The study revealed that about 60% of the subjects were having moderate personal time management while 55% of subjects were having moderate time management in professional life. 79% of the subjects were often stressed at working place and 38% of the subjects stated that they were very stressful. This study revealed the correlation between the time management and nursing stress which is significant at the 0,01 level. This showed that the time management and stress are inversely proportional to each other i.e. the low will be the time management; the greater will be the stress

Innovation in traditional organic nutrient management practices for better soilhealth and higher productivity of brahmi (Bacopa monnieri L.)

This study was conducted at Medicinal Plants Research and Development Centre (MRDC) of Govind Ballabh Pant University of Agriculture and Technology, Pantnagar, District Udham Singh Nagar, India, to examine the effect of Jeevamrit (Bioenhancer) on soil health and herbage yield of brahmi crop (var. CIM- Jagriti) and to optimise its rate of application. The experiment was laid out in randomised block design (RBD), replicated trice. The experimental soil was sandy clay loam in texture, neutral in reaction, having pH 6.9, medium in organic carbon (0.64%), low in available nitrogen (180.78 kg ha-1) and medium in both available phosphorus (20.14 kg ha-1) and potassium (200.64 kg ha-1). Jeevamrit enhances soil nutrient content, improve bulk density and biodiversity by increasing beneficial soil microbes which mineralise the nutrients present in soil and increase their availability. Jeevamrit 4000 l ha-1 can be used as a nutrient source in place of chemical fertilisers and expensive bulky organic manures under organic nutrient management

Driving calmodulin protein towards conformational shift by changing ionization states of select residues

Proteins are complex systems made up of many conformational sub-states which are mainly determined by the folded structure. External factors such as solvent type, temperature, pH and ionic strength play a very important role in the conformations sampled by proteins. Here we study the conformational multiplicity of calmodulin (CaM) which is a protein that plays an important role in calcium signaling pathways in the eukaryotic cells. CaM can bind to a variety of other proteins or small organic compounds, and mediates different physiological processes by activating various enzymes. Binding of calcium ions and proteins or small organic molecules to CaM induces large conformational changes that are distinct to each interacting partner. In particular, we discuss the effect of pH variation on the conformations of CaM. By using the pKa values of the charged residues as a basis to assign protonation states, the conformational changes induced in CaM by reducing the pH are studied by molecular dynamics simulations. Our current view suggests that at high pH, barrier crossing to the compact form is prevented by repulsive electrostatic interactions between the two lobes. At reduced pH, not only is barrier crossing facilitated by protonation of residues, but also conformations which are on average more compact are attained. The latter are in accordance with the fluorescence resonance energy transfer experiment results of other workers. The key events leading to the conformational change from the open to the compact conformation are (i) formation of a salt bridge between the N-lobe and the linker, stabilizing their relative motions, (ii) bending of the C-lobe towards the N-lobe, leading to a lowering of the interaction energy between the two-lobes, (iii) formation of a hydrophobic patch between the two lobes, further stabilizing the bent conformation by reducing the entropic cost of the compact form, (iv) sharing of a Ca+2 ion between the two lobes

Hyper-spectral data based investigations for snow wetness mapping

Spatial information on snow wetness content (SWC) is important for hydrology, climatology applications. Limited work is available on estimation of SWC using optical sensors. In present work, spectral signature characteristics of snow (~145 samples) acquired in winters of three years, using field spectral-radiometer (350–2500 nm) were correlated with synchronized SWC measurements. Correlation is found stronger in Near-Infra-Red (NIR) and Short-Wave-Infrared (SWIR) regions than Visible (VIS). Spectral peak width at 905 and 1240 nm is found negatively correlated with SWC, while positively correlated at 1025 nm. Asymmetry tends towards right as SWC increases and has stable positive correlations as compared to other characteristics. Sensitivity of widely used snow-related indices to SWC is also analyzed. Based on analysis, new ratio method at selected wavelengths is proposed to discriminate dry and wet snow zones using air/ground borne sensors. Proposed methodology is evaluated on air-borne hyper-spectral (AVIRIS-NG) data and 88% overall accuracy with kappa coefficient 77.6 observed after validation with reference observations