8 research outputs found
Toward Singlet Oxygen Delivery at a Measured Rate: A Self-Reporting Photosensitizer
A Bodipy-based
energy transfer cassette with a singlet oxygen reactive
linker between the donor and acceptor modules has an interesting emergent
property, if the acceptor module is also a photosensitizer. Singlet
oxygen produced by the photosensitizer reacts rapidly with the molecule
itself to liberate the energy donor, resulting in an enhanced fluorescence
emission. The result is a self-reporting photosensitizer providing
an assessment of the singlet oxygen production rate under the operational
conditions
Molecular logic gates: The past, present and future
The field of molecular logic gates originated 25 years ago, when A. P. de Silva published a seminal article in Nature. Stimulated by this ground breaking research, scientists were inspired to join the race to simulate the workings of the fundamental components of integrated circuits using molecules. The rules of this game of mimicry were flexible, and have evolved and morphed over the years. This tutorial review takes a look back on and provides an overview of the birth and growth of the field of molecular logics. Spinning-off from chemosensor research, molecular logic gates quickly proved themselves to be more than intellectual exercises and are now poised for many potential practical applications. The ultimate goal of this vein of research became clearer only recently ? to ?boldly go where no silicon-based logic gate has gone before? and seek out a new deeper understanding of life inside tissues and cells
Rotary and linear molecular motors driven by pulses of a chemical fuel
Acid fuels the motion of a threaded ring
A central goal in the construction of molecular-scale machines is the efficient achievement of one-way motion. Erbas-Cakmak
et al.
developed a class of machines that transmit pH changes into the two-stage guided motion of molecular rings threaded on a linear or cyclic axle. The design relies on temporary blocking groups and landing sites along the axle that toggle between active and passive states in response to acid or base. Trichloroacetic acid initiates the first stage of motion until it is decomposed by base in the solution, spurring the second phase.
Science
, this issue p.
340
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Rotary and linear molecular motors driven by pulses of a chemical fuel
Supplementary Data for Rotary and linear molecular motors driven by pulses of a chemical fue