Iterative group-based and difference ranking method for online rating systems with spamming attacks

It is significant to assign reputation scores to users and identify spammers in the bipartite rating networks. In this paper, we propose an Iterative Group-based and Difference Ranking (IGDR) method, which is based on the original Iterative Group-based Ranking (IGR) method. The IGR method considers users grouping behaviors, but it ignores the characteristics of the individual ratings. It is discovered that individual rating characteristics could also contribute to the redistribution of reputation scores of users. The user with a smaller rating deviation will be given a higher reputation score. The proposed method outperforms IGR method ranging from 8% to 163% tested on three real datasets. It also can be applied to deal with big data in a short time

[μ-10,22-Dichloro-3,6-bis­(2-furylmeth­yl)-3,6,14,18-tetra­azatricyclo­[18.3.1.18,12]penta­cosa-1(23),8,10,12(25),13,18,20(24),21-octa­ene-24,25-diolato-κ8 N 3,N 6,O 24,O 25:N 14,N 18,O 24:O 25]bis­[chloridocopper(II)] acetonitrile solvate

The title compound, [Cu2(C31H30Cl2N4O4)Cl2]·CH3CN, was synthesized by cyclo­condensation between N,N′-bis­(2-fur­yl)-N,N′-bis­(3-formyl-5-chloro­salicylaldehyde)ethyl­enediamine and 1,3-diamino­propane in the presence of CuII ions. It is an unsymmetrical dinuclear CuII complex. The coordination geometry for each CuII atom can be discribed as distorted square-pyramidal. The two Cu atoms are bridged by two phenolate O atoms with a Cu⋯Cu distance of 3.0274 (9) Å

Endolymphatic sac tumor: case report and review of the literature

Endolymphatic sac tumor (ELST) is a rare neoplasm which can be encountered sporadically or in Von Hippel-Lindau (VHL) disease. Here we report a sporadic case of ELST in 31-year-old man. Neither the symptoms nor a family history of VHL disease were found in the patient. CT imaging demonstrated an expansile lytic lesion of the mastoid process of the left petrous bone. MR scanning revealed a 5.2 cm × 4.7 cm × 4.2 cm mass which showed hyperintensity on T1- and T2-weighted images. Histologic sections showed a papillary, cystic or glandular architecture. The papillary and glandular structures were lined by a single layer of flattened cuboidal-to-columnar cells. The stroma of the papillary fronds was richly vascularized and chronically inflamed. The tumor showed diffusely positive reactivity with cytokeratin (Pan), cytokeratin 19, cytokeratin 5/6, cytokeratin 7, EMA, vimentin, CD56, and NSE and also showed variable reactivity with glial fibrillary acidic protein (GFAP) and VEGF. The Ki-67 immunostain showed a proliferation index of < 1%. Because the mass was large, it was difficult to extirpate surgically. After surgery, the patient underwent gamma-knife radiosurgery for residual tumor. The findings indicate that ELST is a rare neoplasm with benign histopathological appearance and clinically destructive behavior. Because of the rarity of this tumor, it can easily be confused with other tumors such as paraganglioma, middle ear adenoma, adenocarcinoma, papillary carcinoma of thyroid or choroid plexus papilloma. Owing to its locally aggressive nature, it is difficult to extirpate surgically when it is large

A Dynamic-Order Fractional Dynamic System

Multi-system interaction is an important and difficult problem in physics. Motivated by the experimental result of an electronic circuit element "Fractor", we introduce the concept of dynamic-order fractional dynamic system, in which the differential-order of a fractional dynamic system is determined by the output signal of another dynamic system. The new concept offers a comprehensive explanation of physical mechanism of multi-system interaction. The properties and potential applications of dynamic-order fractional dynamic systems are further explored with the analysis of anomalous relaxation and diffusion processes.Comment: 10 pages, 5 figure

Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway

AbstractMitochondrial aldehyde dehydrogenase 2 (ALDH2) was demonstrated to play cardioprotective roles in cardiovascular diseases. Nonetheless, little is known about the roles and mechanisms of ALDH2 in pressure overload-induced cardiac damages. In this study, we revealed that ALDH2 deficiency overtly exacerbated transverse aortic constriction (TAC)-induced cardiac dysfunction. Cardiomyocyte enlargement was observed in both WT and ALDH2−/− mice in HE-stained myocardial tissue samples at 8weeks post TAC surgery. Mitochondrial morphology and structure were also significantly damaged post TAC surgery and the changes were aggravated in ALDH2−/− TAC hearts. ALDH2 deficiency also depressed myocardial autophagy in hearts at 8weeks post TAC surgery with a potential mechanism of repressing the expression of Beclin-1 and promoting the interaction between Bcl-2 and Beclin-1. These data indicate that ALDH2 deficiency exacerbates the pressure overload induced cardiac dysfunction partly by inhibiting Beclin-1 dependent autophagy pathway.This article is part of a Special Issue entitled: Autophagy and protein quality control in cardiometabolic diseases