13,188 research outputs found
Localizing Gravitational Wave Sources with Single-Baseline Atom Interferometers
Localizing sources on the sky is crucial for realizing the full potential of
gravitational waves for astronomy, astrophysics, and cosmology. We show that
the mid-frequency band, roughly 0.03 to 10 Hz, has significant potential for
angular localization. The angular location is measured through the changing
Doppler shift as the detector orbits the Sun. This band maximizes the effect
since these are the highest frequencies in which sources live several months.
Atom interferometer detectors can observe in the mid-frequency band, and even
with just a single baseline can exploit this effect for sensitive angular
localization. The single baseline orbits around the Earth and the Sun, causing
it to reorient and change position significantly during the lifetime of the
source, and making it similar to having multiple baselines/detectors. For
example, atomic detectors could predict the location of upcoming black hole or
neutron star merger events with sufficient accuracy to allow optical and other
electromagnetic telescopes to observe these events simultaneously. Thus,
mid-band atomic detectors are complementary to other gravitational wave
detectors and will help complete the observation of a broad range of the
gravitational spectrum.Comment: 16 pages, 3 figures, 2 table
Beyond slurry-cast supercapacitor electrodes: PAN/MWNT heteromat-mediated ultrahigh capacitance electrode sheets
Supercapacitors (SCs) have garnered considerable attention as an appealing power source for forthcoming smart energy era. An ultimate challenge facing the SCs is the acquisition of higher energy density without impairing their other electrochemical properties. Herein, we demonstrate a new class of polyacrylonitrile (PAN)/multi-walled carbon tube (MWNT) heteromat-mediated ultrahigh capacitance electrode sheets as an unusual electrode architecture strategy to address the aforementioned issue. Vanadium pentoxide (V2O5) is chosen as a model electrode material to explore the feasibility of the suggested concept. The heteromat V2O5 electrode sheets are produced through one-pot fabrication based on concurrent electrospraying (for V2O5 precursor/MWNT) and electrospinning (for PAN nanofiber) followed by calcination, leading to compact packing of V2O5 materials in intimate contact with MWNTs and PAN nanofibers. As a consequence, the heteromat V2O5 electrode sheets offer three-dimensionally bicontinuous electron (arising from MWNT networks)/ion (from spatially reticulated interstitial voids to be filled with liquid electrolytes) conduction pathways, thereby facilitating redox reaction kinetics of V2O5 materials. In addition, elimination of heavy metallic foil current collectors, in combination with the dense packing of V2O5 materials, significantly increases (electrode sheet-based) specific capacitances far beyond those accessible with conventional slurry-cast electrodes.ope
Anomalous Paramagnetic Effects in the Mixed State of LuNi2B2C
Anomalous paramagnetic effects in dc magnetization were observed in the mixed
state of LuNi2B2C, unlike any reported previously. It appears as a kink-like
feature for H > 30 kOe and becomes more prominent with increasing field. A
specific heat jump at the corresponding temperature suggests that the anomaly
is due to a true bulk transition. A magnetic flux transition from a square to
an hexagonal lattice is consistent with the anomaly.Comment: 5 pages, 4 figure
Capric Acid Inhibits NO Production and STAT3 Activation during LPS-Induced Osteoclastogenesis
Capric acid is a second medium-chain fatty acid, and recent studies have shown that fatty acids are associated with bone density and reduce bone turnover. In this study, we investigated the effects of capric acid on lipopolysaccharide (LPS)-induced osteoclastogenesis in RAW264.7 cells. After treatment with capric acid (1 mM), the number of tartrate resistant acid phosphatase (TRAP)-positive cells decreased significantly. Capric acid reduced LPS-induced TRAP expression, an osteoclast differentiation marker, without inhibiting cell viability. LPS strongly upregulated inducible nitric oxide synthase (iNOS) mRNA levels and nitric oxide (NO) production, whereas capric acid inhibited them. Furthermore, capric acid also inhibited monocyte chemoattractant protein-1 (MCP-1) mRNA expression. Subsequently, we investigated various intracellular signaling proteins, including nuclear factor-κB (NF-κB), c-Jun-N-terminal kinase (JNK), extracellular signal regulated kinase 1/2 (ERK1/2), and signal transducer and activator of transcription 1 (STAT1) and STAT3 associated with osteoclastogenesis. Capric acid had no effects on LPS-induced activation of the NF-κB, JNK, ERK1/2, and STAT1 pathways. However, capric acid inhibited LPS-induced phosphorylation of Ser727 in STAT3. Additionally, stattic (a STAT3 inhibitor) inhibited LPS-induced iNOS and MCP-1 gene expression. In conclusion, we demonstrated that capric acid inhibited LPS-induced osteoclastogenesis by suppressing NO production via the STAT3 pathway. These results suggest that capric acid has important therapeutic implications for treating bone diseases associated with excessive osteoclastogenesis
Substitution for Cu in the electron-doped infinite-layer superconductor Sr0.9La0.1CuO2, Ni reduces Tc much faster than Zn
We report on the effect of substitution for Cu on Tc of electron-doped
infinite-layer superconductors Sr0.9La0.1Cu1-xRxO2, R = Zn and Ni. We found
that Tc was nearly constant until x = 0.03 for R = Zn, while superconductivity
was nearly suppressed for x = 0.02 with dTc/dx = 20 K/% for R = Ni. This
behavior is very similar to that of conventional superconductors. These
findings are discussed in terms of the superconducting gap symmetry in the
cuprate superconductors including another electron-doped superconductor,
(Nd,Ce)2CuO4-y.Comment: 5 pages and 2 EPS figures, [email protected] for material reques
A novel de novo mutation in the serine-threonine kinase STK11 gene in a Korean patient with Peutz-Jeghers syndrome
BACKGROUND: Peutz-Jeghers syndrome (PJS) is an unusual autosomal dominant disorder characterized by mucocutaneous pigmentation and multiple gastrointestinal hamartomatous polyps. Patients with PJS are at an increased risk of developing multi-organ cancer, most frequently those involving the gastrointestinal tract. Germline mutation of the STK11 gene, which encodes a serine-threonine kinase, is responsible for PJS. METHODS: Using DNA samples obtained from the patient and his family members, we sequenced nine exons and flanking intron regions of the STK11 gene using polymerase chain reaction (PCR) and direct sequencing. RESULTS: Sequencing of the STK11 gene in the proband of the family revealed a novel 1-base pair deletion of guanine (G) in exon 6 (c.826delG; Gly276AlafsX11). This mutation resulted in a premature termination at codon 286, predicting a partial loss of the kinase domain and complete loss of the C-terminal domain. We did not observe this mutation in both parents of the PJS patient. Therefore, it is considered a novel de novo mutation. CONCLUSION: The results presented herein enlarge the spectrum of mutations of the STK11 gene by identifying a novel de novo mutation in a PJS patient and further support the hypothesis that STK11 mutations are disease-causing mutations for PJS with or without a positive family history
Electroluminescence of hot electrons in AlGaN/GaN high-electron-mobility transistors under radio frequency operation
Hot electrons in AlGaN/GaN high electron mobility transistors are studied during radio frequency (RF) and DC operation by means of electroluminescence (EL) microscopy and spectroscopy. The measured EL intensity is decreased under RF operation compared to DC at the same average current, indicating a lower hot electron density. This is explained by averaging the DC EL intensity over the measured load line used in RF measurements, giving reasonable agreement. In addition, the hot electron temperature is lower by up to 15% under RF compared to DC, again at least partially explainable by the weighted averaging along the specific load line. However, peak electron temperature under RF occurs at high VDS and low IDS where EL is insignificant suggesting that any wear-out differences between RF and DC stress of the devices will depend on the balance between hot-carrier and field driven degradation mechanisms
Study of hot electrons in AlGaN/GaN HEMTs under RF Class B and Class J operation using electroluminescence
Quantum discord evolution of three-qubit states under noisy channels
We investigated the dissipative dynamics of quantum discord for correlated
qubits under Markovian environments.
The basic idea in the present scheme is that quantum discord is more general,
and possibly more robust and fundamental, than entanglement. We provide three
initially correlated qubits in pure Greenberger-Horne-Zeilinger (GHZ) or W
state and analyse the time evolution of the quantum discord under various
dissipative channels such as:
Pauli channels , , and , as well as
depolarising channels. Surprisingly, we find that under the action of Pauli
channel , the quantum discord of GHZ state is not affected by
decoherence. For the remaining dissipative channels, the W state is more robust
than the GHZ state against decoherence. Moreover, we compare the dynamics of
entanglement with that of the quantum discord under the conditions in which
disentanglement occurs and show that quantum discord is more robust than
entanglement except for phase flip coupling of the three qubits system to the
environment.Comment: 17 pages, 4 figures, accepted for publication in EPJ
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