4,168 research outputs found

    Chapter 15 South Korea’s Green New Deal 2.0

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    In recent years, the Green New Deal has moved from relative obscurity to front and centre of policy discussions and public debates about how to respond to the climate crisis. It has been credited with radically changing the nature of the conversation on climate change and with re-energizing the environmental movement at a critical time. All Green New Deal proposals share an emphasis on the need for governments (rather than markets) to lead the energy transition. However, they differ in other respects. This Handbook analyses the fundamentals underlying all Green New Deals as well as exploring national and regional variations. It is divided into three parts. The first part examines the political economy of the Green New Deal focussing not just on how proposals will be costed but also on opportunities for a fundamental transformation of both national economies and the global economic system. The second part explores issues of justice, which are central to many Green New Deal proposals, including Indigenous rights, racial and gender equity, and justice for the Global South. In the third part, authors detail case studies of Green New Deal proposals and plans at the local, national, and regional level. This book will be an invaluable research and reference volume for students and scholars in economics, politics, sociology, geography, and environmental studies. It should also be of interest to those actively involved in climate and environmental policymaking

    Experts Social Responsibility in the Process of Large-Scale Nature-Transforming National Projects : Focusing on the Case of the Four Major Rivers Restoration Project in Korea

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    This paper is concerned with the social responsibility of experts in the fields of science and technology in the process of large-scale nature-transforming national projects. This paper took the case of the Four Major Rivers Restoration Project in Korea−which has been admired internationally as a Korean-style Green New Deal on the one hand, and has caused domestic controversies especially among experts on the other hand−in order to deal with the issue of experts social responsibility. The research questions raised in this paper include why and how experts should take social responsibility and to what extent they have to be responsible. Through exploration of the case of the Four Major Rivers Project, this paper argues that experts have to claim social responsibility when national policies and projects are associated with scientific and technological elements, since these events hugely impact the daily lives of the public and the condition of the environment and demand large investments of public money. It also underscores the necessity of having socially responsible experts reveal their values and stances based on verifiable evidence and giving the public a chance to determine which set of experts are working for the public good. Experts should be allowed to contest their arguments and positions under conditions where free speech is respected so they can practice social responsibility. Whether this is allowed or not can reveal the level of democracy of a society. The Four Major Rivers Project identifies the importance of experts social responsibility and the conditions for its realization

    AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS

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    While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials. To explore the possibility that concurrent blockade of free radicals and PGE2-mediated inflammation might constitute a safe and effective therapeutic approach to certain neurodegenerative diseases, we have developed 2-hydroxy-5-[2-(4-trifluoromethylphenyl)-ethylaminobezoic acid (AAD-2004) as a derivative of aspirin. AAD-2004 completely removed free radicals at 50 nM as a potent spin trapping molecule and inhibited microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 230 nM. Oral administration of AAD-2004 blocked free radical formation, PGE2 formation, and microglial activation in the spinal motor neurons of SOD1G93A mice. As a consequence, AAD-2004 reduced autophagosome formation, axonopathy, and motor neuron degeneration, improving motor function and increasing life span. In these assays, AAD-2004 was superior to ibuprofen or riluzole. Gastric bleeding was not induced by AAD-2004 even at a dose 400-fold higher than that required to obtain maximal therapeutic efficacy in SOD1G93A mice. Targeting both mPGES-1 and free radicals may be a promising approach to reduce neurodegeneration in ALS and possibly other neurodegenerative diseases

    Chapter 15 South Korea’s Green New Deal 2.0

    Get PDF
    In recent years, the Green New Deal has moved from relative obscurity to front and centre of policy discussions and public debates about how to respond to the climate crisis. It has been credited with radically changing the nature of the conversation on climate change and with re-energizing the environmental movement at a critical time. All Green New Deal proposals share an emphasis on the need for governments (rather than markets) to lead the energy transition. However, they differ in other respects. This Handbook analyses the fundamentals underlying all Green New Deals as well as exploring national and regional variations. It is divided into three parts. The first part examines the political economy of the Green New Deal focussing not just on how proposals will be costed but also on opportunities for a fundamental transformation of both national economies and the global economic system. The second part explores issues of justice, which are central to many Green New Deal proposals, including Indigenous rights, racial and gender equity, and justice for the Global South. In the third part, authors detail case studies of Green New Deal proposals and plans at the local, national, and regional level. This book will be an invaluable research and reference volume for students and scholars in economics, politics, sociology, geography, and environmental studies. It should also be of interest to those actively involved in climate and environmental policymaking

    Introduction: Climate Change, Cosmopolitanism, and Media Politics

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    The four papers shown in this special section have been chosen out of the 20 papers presented in an international conference on the overall topic of Climate Change and Risk Society: New Trends of Megacity Transformation held at Seoul National University from July 9-11, 2014,** with Professor Ulrich Beck who delivered a keynote public lecture Emancipatory Catastrophism: What does it mean to Climate Change and Risk Society at Press Center in the downtown of Seoul in the afternoon of July 8, 2014. Becks concept of global risk society starts from the recognition that modernization has produced new forms of risks that cannot avoid with advanced technology development. Modernization became a root cause of modern risks which are deeply embedded in modern society itself. In particular, global ecological risks threaten the survival of humanity. Perhaps, one of the most critical type of such global risks is climate change, a representative cross-boundary and inter-generational environmental problem

    Meteorin regulates mesendoderm development by enhancing nodal expression

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    During gastrulation, distinct lineage specification into three germ layers, the mesoderm, endoderm and ectoderm, occurs through an elaborate harmony between signaling molecules along the embryonic proximo-distal and anterior-posterior axes, and Nodal signaling plays a key role in the early embryonic development governing embryonic axis formation, mesoderm and endoderm specification, and left-right asymmetry determination. However, the mechanism by which Nodal expression is regulated is largely unknown. Here, we show that Meteorin regulates Nodal expression and is required for mesendoderm development. It is highly expressed in the inner cell mass of blastocysts and further in the epiblast and extra-embryonic ectoderm during gastrulation. Genetic ablation of the Meteorin gene resulted in early embryonic lethality, presumably due to impaired lineage allocation and subsequent cell accumulation. Embryoid body culture using Meteorin-null embryonic stem (ES) cells showed reduced Nodal expression and concomitant impairment of mesendoderm specification. Meteorin-null embryos displayed reduced levels of Nodal transcripts before the gastrulation stage, and impaired expression of Goosecoid, a definitive endoderm marker, during gastrulation, while the proximo-distal and anterior-posterior axes and primitive streak formation were preserved. Our results show that Meteorin is a novel regulator of Nodal transcription and is required to maintain sufficient Nodal levels for endoderm formation, thereby providing new insights in the regulation of mesendoderm allocation.open1113sciescopu
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