Survey observations of emission-line stars in the Orion region

Survey observations were conducted for H alpha-emission stars in the Orion region using the Kiso Schmidt telescope and partly the CTIO Curtis Schmidt telescope. In the area of about 25 square degrees, a total of 236 H alpha-emission objects, mostly supposed to be T Tau type stars, have been detected among which 155 are new ones including 6 non-stellar objects. Celestial coordinates and V-magnitude are measured for the detected objects. Eye estimation of the H alpha-emission intensity is also made at three epochs in a time span of about two years, where notable variation of H alpha intensity was found in 68 out of 236 objects. Besides a remarkable concentration along the northern dark cloud complex, a loose concentration is noticed near the Orion Belt region, fairly well coinciding with the distribution of the Orion OBIb association members. A comparison with the Av-map is also made to see the relationship between the distribution of emission-line objects and that of interstellar dust

Angiopoietin-1 is associated with cerebral vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage

<p>Abstract</p> <p>Background</p> <p>Angiopoietin-1 (Ang-1) and -2 (Ang-2) are keyplayers in the regulation of endothelial homeostasis and vascular proliferation. Angiopoietins may play an important role in the pathophysiology of cerebral vasospasm (CVS). Ang-1 and Ang-2 have not been investigated in this regard so far.</p> <p>Methods</p> <p>20 patients with subarachnoid hemorrhage (SAH) and 20 healthy controls (HC) were included in this prospective study. Blood samples were collected from days 1 to 7 and every other day thereafter. Ang-1 and Ang-2 were measured in serum samples using commercially available enzyme-linked immunosorbent assay. Transcranial Doppler sonography was performed to monitor the occurrence of cerebral vasospasm.</p> <p>Results</p> <p>SAH patients showed a significant drop of Ang-1 levels on day 2 and 3 post SAH compared to baseline and HC. Patients, who developed Doppler sonographic CVS, showed significantly lower levels of Ang-1 with a sustained decrease in contrast to patients without Doppler sonographic CVS, whose Ang-1 levels recovered in the later course of the disease. In patients developing cerebral ischemia attributable to vasospasm significantly lower Ang-1 levels have already been observed on the day of admission. Differences of Ang-2 between SAH patients and HC or patients with and without Doppler sonographic CVS were not statistically significant.</p> <p>Conclusions</p> <p>Ang-1, but not Ang-2, is significantly altered in patients suffering from SAH and especially in those experiencing CVS and cerebral ischemia. The loss of vascular integrity, regulated by Ang-1, might be in part responsible for the development of cerebral vasospasm and subsequent cerebral ischemia.</p