Respon Kelangsungan Hidup Dan Pertumbuhan Larva Terhadap Padat Tebar Ikan Tambakan (Hellostoma Temmincki. C.v)

Fish Tambakan (H. temmincki. CV) is one of the freshwater fish species from the tropics, precisely Southeast Asia. Currently the presence of fish gouramis (H. temmincki. CV) already scarce, and threatened that should be preserved. One effort that can be done to preserve this fish is through cultivation, Density is closely related to the production and the expected growth rate of fish. Activities carried out for 5 months, in hectery Fish Seed Center (BBI) Tempino, District Mestong, Kabupten Muaro. Test fish are fish larvae Tambakan (H. temmincki. CV) of 71 400 individuals. The container used is aquarium measuring 42.5 x 40 x 40 cm, with a height of 10 cm of water as much as 12 aquariums. This research is a design environment completely randomized design (CRD) with 4 treatments and 3 Deuteronomy. The results of this study to the best stocking density is treatment A (200 individuals / liter) which resulted in the percentage of survival of the highest of 86.21%., Average length and weight growth - average yield growth of average length - average 1.50 cm / tail and average weight - average 0159 g / tail and average daily growth - average 0.00396 grams / tail

Association between helicobacter pylori infections with serum gastrin-17 levels in dyspepsia patients

Background: Helicobacter pylori infection is known to interfere with gastric acid secretion. One of the most potent gastrointestinal hormones in triggering gastric acid secretion is gastrin. However, the role of Helicobacter pylori in increasing serum gastrin levels remains controversial. Objective: To determine the relationship between Helicobacter pylori infection with serum gastrin-17 levels in dyspepsia patients in the Endoscopic Unit Department of Internal Medicine, Dr. Soetomo General Hospital Surabaya. Methods: This study used a cross-sectional method that enrolled thirty of dyspepsia patients underwent endoscopy and gastric biopsy in the endoscopic unit of the Department of Internal Medicine Dr. Soetomo General Hospital Surabaya. The patients were divided into two groups, i.e., fifteen patients infected with Helicobacter pylori and not. Determination of Helicobacter pylori infection was using histopathological examination. In the other hands, gastrin-17 fasting serum levels were measured by ELISA method. Results: The results showed median of gastrin-17 serum levels in the H. pylori-infected group 3.97 (0.54-19.43) were higher than the uninfected group 1.28 (0.62-2.71). From the statistical test, there was a significant difference between the two groups (p = 0.002) with the mediumvalue relationship between Helicobacter pylori infection and gastrin-17 serum levels (η = 0.478). Conclusion: There was a relationship between Helicobacter pylori infection with increased of gastrin-17 serum levels in dyspeptic patients. © 2019, Yerevan State Medical University. All rights reserved

The Helicobacter pylori Genome Project : insights into H. pylori population structure from analysis of a worldwide collection of complete genomes

Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk. Here, we provide insights into H. pylori population structure as a part of the Helicobacter pylori Genome Project (HpGP), a multi-disciplinary initiative aimed at elucidating H. pylori pathogenesis and identifying new therapeutic targets. We collected 1011 well-characterized clinical strains from 50 countries and generated high-quality genome sequences. We analysed core genome diversity and population structure of the HpGP dataset and 255 worldwide reference genomes to outline the ancestral contribution to Eurasian, African, and American populations. We found evidence of substantial contribution of population hpNorthAsia and subpopulation hspUral in Northern European H. pylori. The genomes of H. pylori isolated from northern and southern Indigenous Americans differed in that bacteria isolated in northern Indigenous communities were more similar to North Asian H. pylori while the southern had higher relatedness to hpEastAsia. Notably, we also found a highly clonal yet geographically dispersed North American subpopulation, which is negative for the cag pathogenicity island, and present in 7% of sequenced US genomes. We expect the HpGP dataset and the corresponding strains to become a major asset for H. pylori genomics

Association between COVID-19 severity with liver abnormalities: A retrospective study in a referral hospital in Indonesia

Coronavirus disease 2019 (COVID-19) is characterized by an acute respiratory infection with multisystem involvement and the association of its severity to liver function abnormalities is not well characterized. The aim of this study was to assess the association between the severity of COVID-19 patients and liver function abnormalities. This retrospective study included adult patients with confirmed COVID-19, which were classified as non-severe or severe according to World Health Organization guidelines. Liver function test results were compared between the severity groups. A total of 339 patients were included of which 150 (44.25%) were severe cases. The male-to-female ratio was 0.9:1 and 3:2 in the non-severe and severe groups, respectively (p=0.031). Aspartate aminotransferase (AST), alanine transaminase (ALT), and total bilirubin levels and acute liver injury (ALI) incidence were significantly higher in the severe group compared to non-severe group (p<0.001, p<0.001, p=0.025, p=0.014, respectively). In contrast, albumin levels were significantly lower (p=0.001). Multivariate analysis showed that ALI was significantly associated with human immunodeficiency virus (HIV) infection (odds ratio (OR): 5.275; 95% confidence interval (CI): 1.165–23.890, p=0.031), hemoglobin level (OR: 1.214; 95%CI: 1.083–1.361, p=0.001), and hypoalbuminemia (OR: 2.627; 95%CI: 1.283–5.379, p=0.008). Pre-existing liver diseases were present in 6.5% of patients. No significant differences were observed between the groups based on COVID-19 severity and ALI presence. Liver function test abnormalities, including ALI, are more prevalent in patients with severe COVID-19 infection. HIV infection, high hemoglobin levels, and hypoalbuminemia may be potential risk factors for ALI