228 research outputs found

    Gestión de bosques mixtos de pino y roble en escenarios de incertidumbre climática

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    The process-based forest growth model 4C (FORESEE - FORESt Ecosystems in a Changing Environment) was used to analyze the growth of a mixed oak-pine stand [Quercus petraea (Mattuschka) Liebl., Pinus sylvestris L.]. The oak-pine stand is typical for the ongoing forest transformation in the north-eastern lowlands. The pine and the oak trees are 104 and 9 years old, respectively. Three different management scenarios (A, B, C) with different thinning grades and a thinning interval of five years were simulated. Every management scenario was simulated under three different climate scenarios (0K, 2K, 3K) compiled by the regional statistical climate model STAR 2.0 (PIK). For each climate scenario 100 different realisations were generated. The realisations of the climate scenarios encompass the period 2036-2060 and exhibit an increase of mean annual temperature of zero, two and three Kelvin until 2060, respectively. We selected 9 model outputs concerning biomass, growth and harvest which were aggregated to a single total performance index (TPI). The TPI was used to assess the management scenarios with regard to three management objectives (carbon sequestration, intermediate, timber yield) under climate change until 2060. We found out that management scenario A led to the highest TPI concerning the carbon sequestration objective and management scenario C performed best concerning the two other objectives. The analysis of variance in the growth related model outputs showed an increase of climate uncertainty with increasing climate warming. Interestingly, the increase of climate induced uncertainty is much higher from 2 to 3 K than from 0 to 2 K.Se ha utilizado un modelo forestal basado en procesos denominado 4C (FORESEE - FORESt Ecosystems in a Changing Environment) para analizar el crecimiento de un masa forestal con mezcla de Quercus petraea y Pinus sylvestris. Ésta es una mezcla típica en las áreas de transformación forestal en las zonas bajas del noreste de Alemania. Los pinos y los robles tienen una edad de 104 y 9 años respectivamente. Se simularon tres escenarios diferentes de manejo (A, B, C) con diferentes grados de claras e intervalos de clara de 5 años. Cada escenario de manejo fue simulado bajo tres escenarios climáticos (0K, 2K, 3K) los cuales se calcularon por el modelo regional climático estadístico STAR 2.0 (PIK). Se generaron 100 diferentes realizaciones para cada escenario climático. Las realizaciones incluyen el período 2036-2060 y presentan un aumento de la temperatura anual de cero, dos y tres grados Kelvin hasta el año 2060, respectivamente. Seleccionamos 9 salidas del modelo relacionadas con la biomasa, crecimiento y rendimiento que se combinaron en un único índice de rendimiento total (TPI, total performance index). El TPI fue analizado para investigar los escenarios de manejo con respecto a tres objetivos de manejo (secuestro de carbono, máximo rendimiento maderero, y un escenario intermedio a ambos) bajo la influencia de cambio climático hasta el año 2060. Nuestros resultados indican que el escenario A muestra el TPI más alto con respecto al secuestro de carbono, y el escenario C tuvo el mejor resultado respecto a los otros dos objetivos. El análisis de varianza en las salidas relativas al crecimiento mostró que mientras más evoluciona el calentamiento global, más crece la incertidumbre climática. Cabe destacar que el aumento de la incertidumbre inducida por el clima es mucho mayor al aumentar de 2 a 3 K que de 0 a 2 K

    Stimulation of gastrointestinal antibody to Shiga toxin by orogastric immunization in mice

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141579/1/imcb69.pd

    Uncertainty of biomass contributions from agriculture and forestry to renewable energy resources under climate change

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    In the future, Germany's land-use policies and the impacts of climate change on yields will affect the amount of biomass available for energy production. We used recent published data on biomass potentials in the federal states of Germany to assess the uncertainty caused by climate change effects in the potential supply of biomass available for energy production. In this study we selected three climate scenarios representing the maximum, mean and minimum temperature increase for Germany out of 21 CMIP5-projections driven by the Representative Concentration Pathways (RCP) 8.5 scenario. Each of the three selected projections was downscaled using the regional statistical climate model STARS. We analysed the yield changes of four biomass feedstock crops (forest, short-rotation coppices (SRC), cereal straw (winter wheat) and energy maize) for the period 2031–2060 in comparison to 1981–2010. The mean annual yield changes of energy wood from forest and short-rotation coppices were modelled using the process-based forest growth model 4C. The yield changes of winter wheat and energy maize from agricultural production were simulated with the statistical yield model IRMA. Germany's annual biomass potential of 1500 PJ varies between minus 5 % and plus 8 % depending on the climate scenario realisation. Assuming that 1500 PJ of biomass utilisation can be achieved, climate change effects of minus 75 (5 %) PJ or plus 120 (8 %) PJ do not impede overall bioenergy targets of 1287 PJ in 2020 and 1534 PJ in 2050. In five federal states the climate scenarios lead to decreasing yields of energy maize and winter wheat. Impacts of climate scenarios on forest yields are mainly positive and show both positive and negative effects on yields of SRC

    NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity

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    <p>Abstract</p> <p>Background</p> <p>Visceral hypersensitivity is a clinical observation made when diagnosing patients with functional bowel disorders. The cause of visceral hypersensitivity is unknown but is thought to be attributed to inflammation. Previously we demonstrated that a unique set of enteric neurons, colospinal afferent neurons (CANs), co-localize with the NR1 and NR2D subunits of the NMDA receptor as well as with the PAR2 receptor. The aim of this study was to determine if NMDA and PAR2 receptors expressed on CANs contribute to visceral hypersensitivity following inflammation. Recently, work has suggested that dorsal root ganglion (DRG) neurons expressing the transient receptor potential vanilloid-1 (TRPV1) receptor mediate inflammation induced visceral hypersensitivity. Therefore, in order to study CAN involvement in visceral hypersensitivity, DRG neurons expressing the TRPV1 receptor were lesioned with resiniferatoxin (RTX) prior to inflammation and behavioural testing.</p> <p>Results</p> <p>CANs do not express the TRPV1 receptor; therefore, they survive following RTX injection. RTX treatment resulted in a significant decrease in TRPV1 expressing neurons in the colon and immunohistochemical analysis revealed no change in peptide or receptor expression in CANs following RTX lesioning as compared to control data. Behavioral studies determined that both inflamed non-RTX and RTX animals showed a decrease in balloon pressure threshold as compared to controls. Immunohistochemical analysis demonstrated that the NR1 cassettes, N1 and C1, of the NMDA receptor on CANs were up-regulated following inflammation. Furthermore, inflammation resulted in the activation of the PAR2 receptors expressed on CANs.</p> <p>Conclusion</p> <p>Our data show that inflammation causes an up-regulation of the NMDA receptor and the activation of the PAR2 receptor expressed on CANs. These changes are associated with a decrease in balloon pressure in response to colorectal distension in non-RTX and RTX lesioned animals. Therefore, these data suggest that CANs contribute to visceral hypersensitivity during inflammation.</p

    Capillary Assembly of Anisotropic Particles at Cylindrical Fluid-Fluid Interfaces

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    The unique behavior of colloids at liquid interfaces provides exciting opportunities for engineering the assembly of colloidal particles into functional materials. The deformable nature of fluid-fluid interfaces means that we can use the interfacial curvature, in addition to particle properties, to direct self-assembly. To this end, we use a finite element method (Surface Evolver) to study the self-assembly of rod-shaped particles adsorbed at a simple curved fluid-fluid interface formed by a sessile liquid drop with cylindrical geometry. Specifically, we study the self-assembly of single and multiple rods as a function of drop curvature and particle properties such as shape (ellipsoid, cylinder, and spherocylinder), contact angle, aspect ratio, and chemical heterogeneity (homogeneous and triblock patchy). We find that the curved interface allows us to effectively control the orientation of the rods, allowing us to achieve parallel, perpendicular, or novel obliquely orientations with respect to the cylindrical drop. In addition, by tuning particle properties to achieve parallel alignment of the rods, we show that the cylindrical drop geometry favors tip-to-tip assembly of the rods, not just for cylinders, but also for ellipsoids and triblock patchy rods. Finally, for triblock patchy rods with larger contact line undulations, we can achieve strong spatial confinement of the rods transverse to the cylindrical drop due to the capillary repulsion between the contact line undulations of the particle and the pinned contact lines of the sessile drop. Our capillary assembly method allows us to manipulate the configuration of single and multiple rod-like particles and therefore offers a facile strategy for organizing such particles into useful functional materials

    Определение области нестабильных параметров системы микрогравитации, гарантирующих допустимую степень устойчивости

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    На основании найденных значений интервалов коэффициентов характеристического полинома и их зависимостей от нестабильных параметров составляется система неравенств, решение которой дает границы искомой области.Based on the found values of the intervals of the coefficients of the characteristic polynomial and their dependences on unstable parameters, a system of inequalities is drawn up, the solution of which gives the boundaries of the desired region
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