Radially Interrupted Viscous Fingers in a Lifting Hele-Shaw Cell

Viscous fingers have been produced in the lifting Hele-Shaw cell, with concentric circular grooves etched onto the lower plate. The invading fluid (air) enters the defending newtonian fluid - olive oil as fingers proceeding radially inwards towards the centre. The fingers are interrupted at the circular groove, and reform as secondary fingers. The effect of the grooves is to speed up the fingering process considerably and the fingers now reach the centre much faster. We explain this by comparing the variation in velocity of the fingers in the normal HS cell and the grooved cells with time. In the normal HS cell the fingers move fastest on initial formation and slow down later. Since in case of the grooved plate, the fingers reform and receive a boost in their speed each time they encounter a groove, the fingers proceed to the centre faster. PACS nos. 47.20.Gv, 47.54.+r, 68.03.-gComment: 4 pg. 2 fi

N—H⋯N hydrogen bonding in 4,6-diphenyl-2-pyrimidinylamine isolated from the plant Justicia secunda (Acanthaceae)

The title compound, C₁₆H₁₃N₃, isolated from Justicia secunda (Acanthaceae), comprises two molecules (which differ slightly in conformation) in the asymmetric unit of space group P\overline 1. Intermolecular Namino-H...Npyrm interactions (Npyrm is a pyrimidine ring N atom) involve only one of the two donor amino H atoms and pyrimidine N atoms per molecule, forming dimeric units via R²₂(8) rings, with N...N distances of 3.058 (2) and 3.106 (3) Å, and N-H...N angles of 172.7 (18) and 175.8 (17)°. The dimers are linked by C-H...π(arene) contacts, with an H...centroid distance of 2.77 Å and a C-H...centroid angle of 141°

Introduction of d-Glutamate at a Critical Residue of Aβ42 Stabilizes a Prefibrillary Aggregate with Enhanced Toxicity.

The amyloid beta peptide 42 (Aβ42) is an aggregation-prone peptide that plays a pivotal role in Alzheimer's disease. We report that a subtle perturbation to the peptide through a single chirality change at glutamate 22 leads to a pronounced delay in the β-sheet adoption of the peptide. This was accompanied by an attenuated propensity of the peptide to form fibrils, which was correlated with changes at the level of the fibrillary architecture. Strikingly, the incorporation of d-glutamate was found to stabilize a soluble, ordered macromolecular assembly with enhanced cytotoxicity to PC12 cells, highlighting the importance of advanced prefibrillary Aβ aggregates in neurotoxicity

Enhancement of post harvest fruit quality and leaf curl disease tolerance in tomato through hybrid breeding

Development of hybrids tolerant to leaf curl virus disease along with good post harvest/processing traits is the major thrust areas in tomato breeding now-a-days. A study was undertaken following 7 × 7 half diallel mating design utilizing four exotic and three indigenous lines to identify potential donors and crosses, to study the extent of heterobeltiosis and dominance behaviour, and to assess the genetic control of post harvest quality traits along with disease tolerance in tomato. Breeding strategies to improve characters governed by different types of gene action are discussed. Two parental lines, CLN 2777F and CLN 2777E could be utilized further in tomato breeding programme as they were identified as the most promising general combiners for fruit yield, processing quality and ToLCV tolerance. The maximum extent of heterobeltiosis (104.17%) was found in pericarp thickness followed by fruit yield plant-1 (63.57 %) and PDI of ToLCV disease (-60.00 %). The hybrids also exhibited various degrees of dominance effects. The study could also able to identify a promising cross ‘CLN 2777E × CLN 2777F’ which could be recommended for commercial exploitation after critical study in leaf curl disease prone areas of the tropics and sub-tropics

Evaluation of Nutritional Status of Rural Bengalee Primary School Boys (6-9 Years) in Comparison to Indian Children

A cross sectional study was undertaken to determine nutritional status and growth pattern of 410 rural primary school boys (6-9 years of age) belong from lower socioeconomic status according Kuppuswamy's socioeconomic scale (2012) in West Midnapore District of West Bengal. The daily nutritional intake of the children was measured by weighing raw and cooked foods and also by 24 hrs recall method. The body mass indexes (BMI), body composition, protein/calory adequacy status, protein-energy ratio of the primary school boys were measured to assess the nutritional status. The food and nutrient intake of the subjects were compared with their respective Indian values (NNMB, 2002). The diet of rural school boys was found to be imbalanced with plenty intake of milk and lower in intake of cereals, pulses but higher in intake of vegetables than that of their Indian counterpart. It was observed that the diets are predominantly more deficient in calories than protein. Most of the boys had normal body weight and only a little number of boys was overweight or underweight and the protein energy ratio is lower than ICMR recommended value except the age group of 7 years and the maximum percentage (about 20%) of underweight boys is found in the age group of 9 years. It was further observed that there was a significant correlation between body composition and BMI (p<0.001)

Evaluation of health hazards during classroom activities and an ergonomic approach for designing a writing desk for the children of rural primary school

oai:inet.vidyasagar.ac.in:123456789/1098Thesis: Ph.D.,Vidyasagar University, Midnapore, Department of Physiology, 2014Evaluation of health hazards during classroom activities and an ergonomic approach for designing a writing desk for the children of rural primary schoolDepartment of Physiology Vidyasagar University Midnapore INDI

Model-based Personalized Synthetic MR Imaging

Synthetic Magnetic Resonance (MR) imaging predicts images at new design parameter settings from a few observed MR scans. Model-based methods, that use both the physical and statistical properties underlying the MR signal and its acquisition, can predict images at any setting from as few as three scans, allowing it to be used in individualized patient- and anatomy-specific contexts. However, the estimation problem in model-based synthetic MR imaging is ill-posed and so regularization, in the form of correlated Gaussian Markov Random Fields, is imposed on the voxel-wise spin-lattice relaxation time, spin-spin relaxation time and the proton density underlying the MR image. We develop theoretically sound but computationally practical matrix-free estimation methods for synthetic MR imaging. Our evaluations demonstrate excellent ability of our methods to synthetize MR images in a clinical framework and also estimation and prediction accuracy and consistency. An added strength of our model-based approach, also developed and illustrated here, is the accurate estimation of standard errors of regional means in the synthesized images.Comment: 13 pages, 5 figures, 5 table

Prevalence and pattern of amblyopia among children attending at tertiary eye care centre in Eastern India

Background: The objective of this study was to determine the prevalence and pattern of amblyopia of children attending at tertiary eye care centre in eastern India.Methods: A cross-sectional study was conducted from April 2020 to May2021 among children (5-15 years age) at regional institute of ophthalmology, medical college, Kolkata, underwent visual acuity assessment, detailed ocular examinations and cycloplegic refractions.Results: A total of 500 children are taken in the study, out of which 264 (52.8%) were males. The age range was 5-15 years with 479 (95.8%) within the ages of 5 to 10 years. Amblyopia was detected in 57 (11.4%). Refractive amblyopia (58.4%) was the most common type of amblyopia out of which anisometropic amblyopia accounted for 74.6%. Unilateral amblyopia was observed in 80.5%. All the types of amblyopia were more common within the age group of 5-10 years.Conclusions: More common children are affected with amblyopia within the ages of 5 to 10 years with refractive amblyopia