844 research outputs found
On the recent Introduction of outboard engines along the Coromandal coast
Introduction of outboard engines along the Coromandal coast and Pondicherry were studied. A total number of 232 outboard engines have been introduced at 16 fish landing centres in the South Arcot District. The outboard engines are fitted exclusively to catamarans with a length range of 8-10 m operating mainly gill nets, Pannu valai and Mani valai and the encircling bag-net, Eda valai
Feature Extraction Methods by Various Concepts using SOM
Image retrieval systems gained traction with the increased use of visual and media data. It is critical to understand and manage big data, lot of analysis done in image retrieval applications. Given the considerable difficulty involved in handling big data using a traditional approach, there is a demand for its efficient management, particularly regarding accuracy and robustness. To solve these issues, we employ content-based image retrieval (CBIR) methods within both supervised , unsupervised pictures. Self-Organizing Maps (SOM), a competitive unsupervised learning aggregation technique, are applied in our innovative multilevel fusion methodology to extract features that are categorised. The proposed methodology beat state-of-the-art algorithms with 90.3% precision, approximate retrieval precision (ARP) of 0.91, and approximate retrieval recall (ARR) of 0.82 when tested on several benchmark datasets
Marine fisheries of the north-east coast of India during 2008
The north-east region of India comprises of the
states of West Bengal and Orissa. There are about
100 landing centres distributed in these two coastal
states, of which most of them record seasonal fishing.
The estimated marine fish landings in this region was
4.83 lakh t in 2008, which formed about 15% of the
total ‘all India landings’
Marine fisheries of the south-east coast of India during 2008
The south-east coast of India comprising the
states of Andhra Pradesh, Tamil Nadu and
Pondicherry have a total coastline of 2050 km which
is 34% of the total coastline of the country. This region
is more diverse with respect to the number of species
that are landed. In 2007, it was observed that 499
species were landed in Tamil Nadu, 294 in Andhra
Pradesh and 115 in Pondicherry
Identifying clinically significant novel drug candidate for highly prevalent Alzheimer's disease
618-623Pharmacokinetics is very important in target validation and in shifting a lead compound into a drug. It is a cumbersome
process in clinical research. A quantitative personation based on computed, pharmacokinetics, physicochemical properties,
ILOGP, drug-likeness, medicinal chemistry friendliness, bioavailability radar and BOILED-Egg for all the synthesized, 6
novel compounds have been assessed using Swiss ADME. An effective drug can be produced from the physicochemical
properties discussed in this model. The physicochemical properties of all designed Schiff bases of curcumin have been
found to be optimal and so, they are perceived to have acceptable oral absorption and adequate permeability. All the
monomers obeyed the rule of five by Lipinski and the oral bioavailability is accounted worldwide. The desired set of
monomers have been enhanced by effective ADME screening and molecular simulation methods with Microtubuleassociated
protein tau (MAPT) (PDB code: 10636) receptor could represent favourable building blocks as preferable
chemotherapeutic factor in resistance to Alzheimers disease
Identifying clinically significant novel drug candidate for highly prevalent Alzheimer's disease
Pharmacokinetics is very important in target validation and in shifting a lead compound into a drug. It is a cumbersome process in clinical research. A quantitative personation based on computed, pharmacokinetics, physicochemical properties, ILOGP, drug-likeness, medicinal chemistry friendliness, bioavailability radar and BOILED-Egg for all the synthesized, 6 novel compounds have been assessed using Swiss ADME. An effective drug can be produced from the physicochemical properties discussed in this model. The physicochemical properties of all designed Schiff bases of curcumin have been found to be optimal and so, they are perceived to have acceptable oral absorption and adequate permeability. All the monomers obeyed the rule of five by Lipinski and the oral bioavailability is accounted worldwide. The desired set of monomers have been enhanced by effective ADME screening and molecular simulation methods with Microtubuleassociated protein tau (MAPT) (PDB code: 10636) receptor could represent favourable building blocks as preferable chemotherapeutic factor in resistance to Alzheimers disease
Identification of a Novel Human Peroxisomal 2,4-Dienoyl-CoA Reductase Related Protein Using the M13 Phage Protein VI Phage Display Technology
TIN-X:target importance and novelty explorer
Abstract
Motivation
The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins.
Results
We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty.
Availability and Implementation
http://www.newdrugtargets.org
</jats:sec
- …