Normalizers of Irreducible Subfactors

We consider normalizers of an irreducible inclusion $N\subseteq M$ of $\mathrm{II}_1$ factors. In the infinite index setting an inclusion $uNu^*\subseteq N$ can be strict, forcing us to also investigate the semigroup of one-sided normalizers. We relate these normalizers of $N$ in $M$ to projections in the basic construction and show that every trace one projection in the relative commutant $N'\cap$ is of the form $u^*e_Nu$ for some unitary $u\in M$ with $uNu^*\subseteq N$. This enables us to identify the normalizers and the algebras they generate in several situations. In particular each normalizer of a tensor product of irreducible subfactors is a tensor product of normalizers modulo a unitary. We also examine normalizers of irreducible subfactors arising from subgroup--group inclusions $H\subseteq G$. Here the normalizers are the normalizing group elements modulo a unitary from $L(H)$. We are also able to identify the finite trace $L(H)$-bimodules in $\ell^2(G)$ as double cosets which are also finite unions of left cosets.Comment: 33 Page

Responding to accents after experiencing interactive or mediated speech

Very little known is about how speakers learn about and/or respond to speech experienced without the possibility for interaction. This paper reports an experiment which considers the effects of two kinds of exposure to speech (interactive or non-interactive mediated) on Scottish English speakers’ responses to another accent (Southern British English), for two processing tasks, phonological awareness and speech production. Only marginal group effects are found according to exposure type. The main findings show a difference between subjects according to exposure type before exposure, and individual shifts in responses to speech according to exposure type

Dissecting the Genetic Basis of Variation in Drosophila Sleep Using a Multiparental QTL Mapping Resource

There is considerable variation in sleep duration, timing and quality in human populations, and sleep dysregulation has been implicated as a risk factor for a range of health problems. Human sleep traits are known to be regulated by genetic factors, but also by an array of environmental and social factors. These uncontrolled, non-genetic effects complicate powerful identification of the loci contributing to sleep directly in humans. The model system, Drosophila melanogaster, exhibits a behavior that shows the hallmarks of mammalian sleep, and here we use a multitiered approach, encompassing high-resolution QTL mapping, expression QTL data, and functional validation with RNAi to investigate the genetic basis of sleep under highly controlled environmental conditions. We measured a battery of sleep phenotypes in >750 genotypes derived from a multiparental mapping panel and identified several, modest-effect QTL contributing to natural variation for sleep. Merging sleep QTL data with a large head transcriptome eQTL mapping dataset from the same population allowed us to refine the list of plausible candidate causative sleep loci. This set includes genes with previously characterized effects on sleep and circadian rhythms, in addition to novel candidates. Finally, we employed adult, nervous system-specific RNAi on the Dopa decarboxylase, dyschronic, and timeless genes, finding significant effects on sleep phenotypes for all three. The genes we resolve are strong candidates to harbor causative, regulatory variation contributing to sleep

Dissecting the Genetic Basis of Variation in Drosophila Sleep Using a Multiparental QTL Mapping Resource

This work is licensed under a Creative Commons Attribution 4.0 International License.There is considerable variation in sleep duration, timing and quality in human populations, and sleep dysregulation has been implicated as a risk factor for a range of health problems. Human sleep traits are known to be regulated by genetic factors, but also by an array of environmental and social factors. These uncontrolled, non-genetic effects complicate powerful identification of the loci contributing to sleep directly in humans. The model system, Drosophila melanogaster, exhibits a behavior that shows the hallmarks of mammalian sleep, and here we use a multitiered approach, encompassing high-resolution QTL mapping, expression QTL data, and functional validation with RNAi to investigate the genetic basis of sleep under highly controlled environmental conditions. We measured a battery of sleep phenotypes in >750 genotypes derived from a multiparental mapping panel and identified several, modest-effect QTL contributing to natural variation for sleep. Merging sleep QTL data with a large head transcriptome eQTL mapping dataset from the same population allowed us to refine the list of plausible candidate causative sleep loci. This set includes genes with previously characterized effects on sleep and circadian rhythms, in addition to novel candidates. Finally, we employed adult, nervous system-specific RNAi on the Dopa decarboxylase, dyschronic, and timeless genes, finding significant effects on sleep phenotypes for all three. The genes we resolve are strong candidates to harbor causative, regulatory variation contributing to sleep

A remark on the similarity and perturbation problems

In this note we show that Kadison's similarity problem for C*-algebras is equivalent to a problem in perturbation theory: must close C*-algebras have close commutants?Comment: 6 Pages, minor typos fixed. C. R. Acad. Sci. Canada, to appea

Toward autonomous architecture: The convergence of digital design, robotics, and the built environment

The way we design, construct, and inhabit buildings is changing—moving toward greater integration of robotic and autonomous systems that challenge our preconceived notions of how buildings are made, what they are, or what they should be

Antioxidant activity of β-lactoglobulin and its modified derivatives

Both native ss-lactoglobulin and its modified derivatives (Figure 1) exhibited antioxidant activity when assessed by the FRAP assay (which measures total reducing power of the sample). A positive correlation was observed between antioxidant activity and protein concentration in all samples. Compared to the native protein, the concentration dependence of the antioxidant activity was significantly greater when ss-lactoglobulin was modified with the Maillard reaction (p=0.000) and Enzyme hydrolysis (p=0.022)....<br /

Reproductive ecology of the Mountain Dragon, Rankinia (Tympanocryptis) diemensis (Reptilia: Squamata: Agamidae) in Tasmania

The mountain dragon, Rankinta (7ympanocryptis) diemensis (Gray, 1841), is the only member of the Agamidae in Tasmania. It occurs in some of the coldest regions occupied by any dragon in Australia, and is found in a variety of habitats ranging from coastal heath to alpine scrub. This paper examines the reproductive ecology of R. diemensis in the most southerly range of its distribution, providing baseline data on timing of reproductive events, reproductive cycles, nesting behaviour and ovipositioning, clutch characteristics and incubation conditions. Winter torpor lasts approximately seven months with males emerging in early September and spermatogenesis occurring from September-November. Females emerge later, with vitellogenesis occurring from September-December. Gravid females may be found between October and January, but females are non-vitellogenic from late December until the following season. The first clutch is typically laid from October--December, with a variable clutch size (2-11 eggs). Females store sperm and a second clutch may be laid five weeks after the first. Eggs incubated in artificial enclosures at low altitude hatched after 72--106 days, after experiencing an average daily temperature of 19°-22°C, and a range of 50-39°C