A preliminary multiple case report of neurocognitive training for children with AD/HD in China

This preliminary multiple case study examined the behavioral outcomes of neurocognitive training on children with attention-deficit/hyperactivity disorder (AD/HD) in China, as well as parent acceptance of the treatment. The training approach targeted working memory, impulse control, and attention/relaxation (via brain electrical activity). Outcome measures included overt behavior as rated by parents and teachers, AD/HD symptom frequency, and parent opinion/feedback. Training was completed by five individuals and delivered via a themed computer game with electroencephalogram (EEG) input via a wireless, single-channel, dry-sensor, portable measurement device. The objective (i.e., training outcomes and EEG) and subjective (i.e., parent ratings/feedback and teacher ratings) data suggested that use of the neurocognitive training resulted in reduced AD/HD behaviors and improvement in socially meaningful outcomes. The parents expressed satisfaction with the training procedure and outcomes. It is concluded that the innovative neurocognitive training approach is effective for improving behavior and reducing symptoms of AD/HD for children in China

Predicting functional outcomes after stroke: An observational study of acute single-channel EEG

Background: Early and objective prediction of functional outcome after stroke is an important issue in rehabilitation. Electroencephalography (EEG) has long been utilized to describe and monitor brain function following neuro-trauma, and technological advances have improved usability in the acute setting. However, skepticism persists whether EEG can provide the same prognostic value as neurological examination. Objective: The current cohort study examined the relationship between acute single-channel EEG and functional outcomes after stroke. Methods: Resting-state EEG recorded at a single left pre-frontal EEG channel (FP1) was obtained from 16 adults within 72 h of first stroke. At 30 and 90 days, measures of disability (modified Rankin Scale; mRS) and involvement in daily activities (modified Barthel Index; mBI) were obtained. Acute EEG measures were correlated with functional outcomes and compared to an early neurological examination of stroke severity using the National Institute of Health Stroke Scale (NIHSS). Classification of good outcomes (mRS ≤1 or mBI ≥95) was also examined using Receiver Operator Curve analyses. Results: One-third to one-half of participants experienced incomplete post-stroke recovery, depending on the time point and measure. Functional outcomes correlated with acute theta values (rs 0.45–0.60), with the strength of associations equivalent to previously reported values obtained from conventional multi-channel systems. Acute theta values ≥0.25 were associated with good outcomes, with positive (67-83%) and negative predictive values (70-90%) comparable to those obtained using the NIHSS. Conclusions: Acute, single-channel EEG can provide unique, non-overlapping clinical information, which may facilitate objective prediction of functional outcome after stroke

Does training on inhibitory tasks influence alcohol consumption and attitudes?

Response inhibition - the suppression of a prepotent or ongoing action - is an executive function central to the regulation of behaviour. Response inhibition can be assessed in the laboratory using the Go/No-go or Stop-Signal tasks which both assess the capacity to withhold an inappropriate response. In the Go/No-go task, participants are required to respond rapidly to Go stimuli but to withhold that response upon No-go stimuli. In the Stop-Signal task, participants are required to respond to Go stimuli but to withhold the response when an auditory stop signal occurs subsequent to the Go stimulus

Familial analysis of MMN in cannabis users: A case study

Abstract presented at the 23rd Australasian Society for Psychophysiology Conference, 20-22 Nov 2013, Wollongong, Australi

An investigation of mismatch negativity in current and ex-cannabis users using a feature controlled method

Abstract presented at the 23rd Australasian Society for Psychophysiology Conference, 20-22 Nov 2013, Wollongong, Australi

Atypical interference control in children with AD/HD with elevated theta/beta ratio

The theta/beta ratio (TBR) is a major area of interest within electroencephalogram (EEG) research in AD/HD. While researchers suggest a prognostic role for TBR in AD/HD, its relationship to behavior remains uncertain. Recent evidence suggests that elevated TBR in AD/HD may be related to atypical inhibition, particularly at an attentional level. This study aimed to examine the performance on three inhibitory tasks of children with AD/HD. Fifty-eight children with AD/HD participated, divided into an elevated TBR (ET) group and a control group (CT). A behavioral disassociation was found − compared to CT, ET showed more difficulty in inhibiting surrounding stimuli but had less day-to-day inhibitory issues measured by BRIEF. There was no significant group difference on response inhibition. The results support the prognostic value of TBR in AD/HD. Elevated TBR may be an inhibitory biomarker; further studies are needed to explore the behavioral implications in patients without elevated TBR

Applying Budd's model to partnership

Over the last decade, the notions of workplace partnership and labour-management cooperation have resulted in distinctive and vociferous debates regarding forms of employee voice in the UK. It is proposed that there is a need to reconsider how we actually evaluate both the process and outcomes of partnership. This article reports on detailed case studies conducted in three diverse banking organizations in order to understand more about the process and outcomes of partnership. The study then applies the 'efficiency, equity, voice' framework developed by Budd, which has not been widely employed in industrial relations research. Accordingly, the article examines if and how partnership contributes to the balancing of efficiency, equity and voice. Judged in this light, the case studies demonstrate various degrees of success in terms of the extent to which partnership has facilitated voice and promoted more considered decision-making, for both management and employees. The article also demonstrates the usefulness of the Budd framework as a device in analysing employment relations processes and outcomes

Winners and losers as mangrove, coral and seagrass ecosystems respond to sea-level rise in Solomon Islands

A 2007 earthquake in the western Solomon Islands resulted in a localised subsidence event in which sea level (relative to the previous coastal settings) rose approximately 30-70 cm, providing insight into impacts of future rapid changes to sea level on coastal ecosystems. Here, we show that increasing sea level by 30-70 cm can have contrasting impacts on mangrove, seagrass and coral reef ecosystems. Coral reef habitats were the clear winners with a steady lateral growth from 2006-2014, yielding a 157% increase in areal coverage over seven years. Mangrove ecosystems, on the other hand, suffered the largest impact through a rapid dieback of 35% (130 ha) of mangrove forest in the study area after subsidence. These forests, however, had partially recovered seven years after the earthquake albeit with a different community structure. The shallow seagrass ecosystems demonstrated the most dynamic response to relative shifts in sea level with both losses and gains in areal extent at small scales of 10-100 m. The results of this study emphasize the importance of considering the impacts of sea-level rise within a complex landscape in which winners and losers may vary over time and space

Consistency of the posterior distribution in generalized linear inverse problems

For ill-posed inverse problems, a regularised solution can be interpreted as a mode of the posterior distribution in a Bayesian framework. This framework enriches the set the solutions, as other posterior estimates can be used as a solution to the inverse problem, such as the posterior mean that can be easier to compute in practice. In this paper we prove consistency of Bayesian solutions of an ill-posed linear inverse problem in the Ky Fan metric for a general class of likelihoods and prior distributions in a finite dimensional setting. This result can be applied to study infinite dimensional problems by letting the dimension of the unknown parameter grow to infinity which can be viewed as discretisation on a grid or spectral approximation of an infinite dimensional problem. Likelihood and the prior distribution are assumed to be in an exponential form that includes distributions from the exponential family, and to be differentiable. The observations can be dependent. No assumption of finite moments of observations, such as expected value or the variance, is necessary thus allowing for possibly non-regular likelihoods, and allowing for non-conjugate and improper priors. If the variance exists, it may be heteroscedastic, namely, it may depend on the unknown function. We observe quite a surprising phenomenon when applying our result to the spectral approximation framework where it is possible to achieve the parametric rate of convergence, i.e the problem becomes self-regularised. We also consider a particular case of the unknown parameter being on the boundary of the parameter set, and show that the rate of convergence in this case is faster than for an interior point parameter.Comment: arXiv admin note: substantial text overlap with arXiv:1110.301