1,292 research outputs found
Instruction of Hearing Impaired Students in School Instrumental Music Programs
Despite several major advances in education for people who are deaf or hearing impaired, there are still some pervasive negative attitudes and perceptions in the education world towards this community of students. The purpose of this study was to discover the attitudes and perceptions that band directors in Mississippi public schools have towards hearing impaired students participating in instrumental ensembles. This study utilized a survey that was sent to every director in the state. The survey contained several questions pertaining to whether directors had ever had a hearing impaired student in their ensembles before, what accommodations were made for those that have, and whether directors would be likely to attend workshops and seminars concerning hearing impaired students as they relate to the musical world.
The results indicate that there are indeed negative attitudes among some directors towards hearing impaired students participating in instrumental ensembles, and there is an unwillingness to learn more about hearing impaired students, as well as an unwillingness to be taught effective ways to teach these students music. Despite the negative attitudes, though, the majority of participants reported that they have little to no issues with hearing impaired students participating in their ensembles. The general response towards educational workshops was less than enthusiastic, though. This is quite concerning. If the attitude towards hearing impaired students in music is ever going to change, it is going to take a lot of effort and a lot of education
MicroPulseâą transscleral cyclophotocoagulation in the treatment of canine glaucoma: Preliminary results (12 dogs)
Objective: To describe the clinical application and effect of MicroPulseâą transscleral cyclophotocoagulation (MPâTSCPC) in dogs with glaucoma.
Animals studied: Twelve dogs with primary (n = 8) or secondary (n = 4) glaucoma, aged 2â13 years (mean ± SD, 7.2 ± 3.8 years).
Procedures: MPâTSCPC was performed under sedation or general anesthesia. Laser duty cycle was 31.3%, laser power varied from 2000â2800 mW, and each hemisphere was treated for 90â180 seconds. The probe was applied to each quadrant in a âsweeping motion,â sparing the 3 and 9 o\u27clock positions.
Results: The number of MPâTSCPC procedures per eye varied from 1 to 3 (1.4 ± 0.7). Intraocular pressure (IOP) was controlled (\u3c25 mm Hg) in 11/12 dogs (92%) within 1â15 days postâoperatively. The IOP control at 1 month and the duration between repeated procedures were significantly greater in eyes treated with high energy laser (2800 mW) compared to 2000â2500 mW. Longâterm followâup (315.3 ± 100.7 days) showed controlled IOP in 5/12 (42%) and vision retention in 4/8 (50%) dogs. In unsuccessful cases, loss of IOP control or vision loss occurred within 3â245 days (109.1 ± 93.7 days) and 28â261 days (114 ± 101.6 days), respectively, resulting in a salvage procedure in 6 dogs. Complications were as follows: corneal hypoesthesia (92%), anterior uveitis (67%), postâoperative ocular hypertension (50%), neurotrophic corneal ulcer (25%), keratoconjunctivitis sicca (8%), and rubeosis iridis (8%).
Conclusions: MPâTSCPC is a viable tool for managing canine glaucoma, although further studies are required to improve the longâterm effect and reduce the complication rate
Mapping the Hot Spots: Zoning Approaches to Space Analysis
This poster examines a preliminary approach to space design developed and implemented in Eastern Kentucky Universityâs Noel Studio for Academic Creativity. The approach discussed here is entitled âHot Spots,â which has allowed the research team to observe trends in space usage and composing activities among students. The Hot Spots approach has yielded valuable insights into the design of flexible learning spaces that provide a point of reflection for the future
Lack of effect of a topical regenerative agent on re-epithelialization rate of canine spontaneous chronic corneal epithelial defects: A randomized, double-masked, placebo-controlled study
Spontaneous chronic corneal epithelial defects (SCCEDs) are characteristic ulcers in dogs that are refractory to healing. The aim of the study was to evaluate the use of a topical regenerative agent to promote healing of SCCEDs. Nineteen dogs (20 eyes) were randomized to receive either regenerative agent (10 eyes) or placebo (10 eyes) every 48 h following corneal debridement, which was repeated 1 week later if the SCCED had not yet healed. The mean ± standard deviation time to re-epithelialization was 17.3 ± 12.8 days for the group treated with a topical regenerative agent and 19.3 ± 11.7 days for the group treated with a placebo; the cumulative healing rates were not statistically different (P \u3e 0.650). A positive association was found between the initial size of the ulcer and the time to re-epithelialization (r = 0.555, P = 0.011). Although well tolerated by dogs, there was no therapeutic advantage in using a topical regenerative agent for re-epithelialization of SCCEDs
Nonlinear Scattering of a Bose-Einstein Condensate on a Rectangular Barrier
We consider the nonlinear scattering and transmission of an atom laser, or
Bose-Einstein condensate (BEC) on a finite rectangular potential barrier. The
nonlinearity inherent in this problem leads to several new physical features
beyond the well-known picture from single-particle quantum mechanics. We find
numerical evidence for a denumerably infinite string of bifurcations in the
transmission resonances as a function of nonlinearity and chemical potential,
when the potential barrier is wide compared to the wavelength of oscillations
in the condensate. Near the bifurcations, we observe extended regions of
near-perfect resonance, in which the barrier is effectively invisible to the
BEC. Unlike in the linear case, it is mainly the barrier width, not the height,
that controls the transmission behavior. We show that the potential barrier can
be used to create and localize a dark soliton or dark soliton train from a
phonon-like standing wave.Comment: 15 pages, 15 figures, new version includes clarification of
definition of transmission coefficient in general nonlinear vs. linear cas
A systematic review of factors influencing habitat connectivity and biodiversity along road and rail routes in temperate zones
This systematic review, part funded by Network Rail Ltd (UK), considers the role of transportation corridors in habitat connectivity within temperate climates, through verge habitat, surrounding matrix, movement along and across the corridor, the wider landscape context and management practices. PICO terms were developed for the bibliographic search on 15/11/22 using Web of Science (all databases), yielding 168 studies for review. The risk of bias was minimised by excluding non-peer reviewed papers. Large and exotic taxa were excluded due to a focus on temperate zones, as were studies on invasive species and climate change where the primary focus was not ecological connectivity. Emergent themes were used to structure the paper. Results indicate that transportation corridors have significant potential for habitat connectivity, especially for generalist and open-specialist species, which favour early to mid-successional habitats. However, physiology is a key determinant in dispersal ability. Vegetation management should consider representative communities rather than individual species. Gaps exist in the range of taxa studied, understanding of seasonal variations and lifecycle stages supported in verges, survival factors such as predation and disease and changes to community structure. Rail environments are under-represented and there is limited knowledge on the relative impacts of vegetation management regimes
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Dissemination of Mycobacterium abscessus via global transmission networks.
Mycobacterium abscessus, a multidrug-resistant nontuberculous mycobacterium, has emerged as a major pathogen affecting people with cystic fibrosis (CF). Although originally thought to be acquired independently from the environment, most individuals are infected with one of several dominant circulating clones (DCCs), indicating the presence of global transmission networks of M. abscessus. How and when these clones emerged and spread globally is unclear. Here, we use evolutionary analyses of isolates from individuals both with and without CF to reconstruct the population history, spatiotemporal spread and recent transmission networks of the DCCs. We demonstrate synchronous expansion of six unrelated DCCs in the 1960s, a period associated with major changes in CF care and survival. Each of these clones has spread globally as a result of rare intercontinental transmission events. We show that the DCCs, but not environmentally acquired isolates, exhibit a specific smoking-associated mutational signature and that current transmission networks include individuals both with and without CF. We therefore propose that the DCCs initially emerged in non-CF populations but were then amplified and spread through the CF community. While individuals with CF are probably the most permissive host, non-CF individuals continue to play a key role in transmission networks and may facilitate long-distance transmission.Funding for this work was provided by The Wellcome Trust (investigator award no. 107032/Z/15/Z to R.A.F.), Fondation Botnar (Programme grant no. 6063) and the UK CF Trust (Innovation Hub award no. 001; Strategic Research Centre award no. 010). M.S., N.A.H. and R.M.D. acknowledge the Cystic Fibrosis Foundation for funding
Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis
The finding of TDP-43 as a major component of ubiquitinated protein inclusions in amyotrophic lateral sclerosis (ALS) has led to the identification of 30 mutations in the transactive response-DNA binding protein (TARDBP) gene, encoding TDP-43. All but one are in exon 6, which encodes the glycine-rich domain. The aim of this study was to determine the frequency of TARDBP mutations in a large cohort of motor neurone disease patients from Northern England (42 non-superoxide dismutase 1 (SOD1) familial ALS (FALS), nine ALS-frontotemporal dementia, 474 sporadic ALS (SALS), 45 progressive muscular atrophy cases). We identified four mutations, two of which were novel, in two familial (FALS) and two sporadic (SALS) cases, giving a frequency of TARDBP mutations in non-SOD1 FALS of 5% and SALS of 0.4%. Analysis of clinical data identified that patients had typical ALS, with limb or bulbar onset, and showed considerable variation in age of onset and rapidity of disease course. However, all cases had an absence of clinically overt cognitive dysfunction
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