8 research outputs found
Langfristige wasserwirtschaftliche Aufgaben in Bayern
SIGLETIB: in RN 6966 (3) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
100 Jahre Bayerisches Landesamt fuer Wasserwirtschaft Bericht ueber die Festveranstaltungen
TIB: RN 5546 (1979,3) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman
Einfluss von Schneefeldsprengungen auf die Erosion
SIGLETIB: RN 5546 (1981,8)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
Mutagenitaet polycyclischer Kohlenwasserstoffe Abschlussbericht PCK 15. Zeitraum: 1.1.1979-31.12.1980
SIGLETechnische Informationsbibliothek Hannover: AC 5850 (1980). / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
Mutagenitaet der polycyclischen Kohlenwasserstoffe (PCK) Abschlussbericht PCK-11.1978
SIGLETechnische Informationsbibliothek Hannover: AC 5850 (1978). / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman
Increased cytochrome P-450 activity in Aspergillus fumigatus after xenobiotic exposure
Microsomal fractions were isolated from Aspergillus fumigatus cultures that had been treated with dimethylsulphoxide (DMSO), ethanol, benzopyrene, phenobarbital or naphthalene. All these xenobiotics increased microsomal cytochrome P-450 content. Cytochrome P-450 reductase activity remained unaffected and no alteration in the microsomal protein profile was detectable by SDS PAGE. Benzopyrene, dimethylaniline, hexobarbitol and p-nitroanisole were metabolised by A. fumigatus microsomes, while aniline, ethoxyresorufin and pentoxyresorufin were not. No xenobiotic elicited a more specific oxidation of any of the substrates. A. fumigatus microsomes also catalyzed the cell-free biosynthesis of ergosterol and quantitative analysis of assay metabolites showed that exposure to ethanol, benzopyrene or phenobarbitone in vivo resulted in enhanced ergosterol biosynthesis in vitro