448 research outputs found
Quantum rainbow scattering at tunable velocities
Elastic scattering cross sections are measured for lithium atoms colliding
with rare gas atoms and SF6 molecules at tunable relative velocities down to
~50 m/s. Our scattering apparatus combines a velocity-tunable molecular beam
with a magneto-optic trap that provides an ultracold cloud of lithium atoms as
a scattering target. Comparison with theory reveals the quantum nature of the
collision dynamics in the studied regime, including both rainbows as well as
orbiting resonances
Robotic-assisted laparoscopic extended pelvic lymph node dissection for prostate cancer: surgical technique and experience with the first 99 cases
BACKGROUND: To date, there is still a paucity of data in the literature on robotic-assisted laparoscopic extended pelvic lymph node dissection (RALEPLND) in patients with prostate cancer. OBJECTIVE: To assess the technical feasibility of RALEPLND and to present our surgical technique. DESIGN, SETTING, AND PARTICIPANTS: From April 2006 to March 2008, we performed RALEPLND in 99 patients prior to robotic-assisted laparoscopic radical prostatectomy. Indications for RALEPLND were a prostate-specific antigen (PSA) >/=10 ng/ml or a preoperative Gleason score >/=7. The data were evaluated retrospectively. SURGICAL PROCEDURE: The transperitoneal approach was used in all cases. In order to gain optimal access to the common iliac bifurcation, the five trocars were placed in a more cephalad position than in patients undergoing radical prostatectomy without RALEPLND. After identification of important landmarks, the lymphatics covering the external iliac vein, the obturator lymphatic packet, and the lymphatics overlying the internal iliac artery were removed on both sides. MEASUREMENTS: The total lymph node yield, the frequency of lymph node metastases, and the complication rate. RESULTS AND LIMITATIONS: The median patient age was 64 yr (range: 45-78). The median preoperative PSA level was 7.7 ng/ml (range: 1.5-84.6). The median number of lymph nodes harvested was 19 (range: 8-53). In 16 patients (16%), we found lymph node metastasis. Complications occurred in seven patients (7%). CONCLUSIONS: RALEPLND is feasible, and its lymph node yield is well in the range of open series. The robotic-assisted laparoscopic approach in itself does not seem to limit a surgeon's ability to perform a complete extended pelvic lymph node dissection
On field theory quantization around instantons
With the perspective of looking for experimentally detectable physical
applications of the so-called topological embedding, a procedure recently
proposed by the author for quantizing a field theory around a non-discrete
space of classical minima (instantons, for example), the physical implications
are discussed in a ``theoretical'' framework, the ideas are collected in a
simple logical scheme and the topological version of the Ginzburg-Landau theory
of superconductivity is solved in the intermediate situation between type I and
type II superconductors.Comment: 27 pages, 5 figures, LaTe
Mappings of least Dirichlet energy and their Hopf differentials
The paper is concerned with mappings between planar domains having least
Dirichlet energy. The existence and uniqueness (up to a conformal change of
variables in the domain) of the energy-minimal mappings is established within
the class of strong limits of homeomorphisms in the
Sobolev space , a result of considerable interest in the
mathematical models of Nonlinear Elasticity. The inner variation leads to the
Hopf differential and its trajectories.
For a pair of doubly connected domains, in which has finite conformal
modulus, we establish the following principle:
A mapping is energy-minimal if and only if
its Hopf-differential is analytic in and real along the boundary of .
In general, the energy-minimal mappings may not be injective, in which case
one observes the occurrence of cracks in . Nevertheless, cracks are
triggered only by the points in the boundary of where fails to be
convex. The general law of formation of cracks reads as follows:
Cracks propagate along vertical trajectories of the Hopf differential from
the boundary of toward the interior of where they eventually terminate
before making a crosscut.Comment: 51 pages, 4 figure
Exact beta function from the holographic loop equation of large-N QCD_4
We construct and study a previously defined quantum holographic effective
action whose critical equation implies the holographic loop equation of large-N
QCD_4 for planar self-avoiding loops in a certain regularization scheme. We
extract from the effective action the exact beta function in the given scheme.
For the Wilsonean coupling constant the beta function is exacly one loop and
the first coefficient agrees with its value in perturbation theory. For the
canonical coupling constant the exact beta function has a NSVZ form and the
first two coefficients agree with their value in perturbation theory.Comment: 42 pages, latex. The exponent of the Vandermonde determinant in the
quantum effective action has been changed, because it has been employed a
holomorphic rather than a hermitean resolution of identity in the functional
integral. Beta function unchanged. New explanations and references added,
typos correcte
Evaluation of a prostate cancer e-health-tutorial
Hintergrund: Angesichts verschiedener Behandlungsoptionen ist die Information und Therapieentscheidung beim lokalisierten Prostatakarzinom eine Herausforderung. Die digitale Informationstechnologie bietet im Vergleich zu gedruckten Informationen mehr Möglichkeiten, die Information und die Patientenkommunikation bedarfsgerecht zu gestalten.
Ziele: Zur Unterstützung der Therapieentscheidung und der Kommunikation mit Patienten ist in der deutschsprachigen Schweiz ein Online-Tutorial in einem systematischen Prozess entwickelt und in einer Pilotstudie getestet worden. In der Evaluation interessierten die Nutzerzufriedenheit, die Erfüllung der Informationsbedürfnisse, die Vorbereitung auf die Therapieentscheidung und deren subjektive Qualität.
Material und Methoden: Die Plattform wurde in einem iterativen Prozess mittels Fokusgruppen mit Ärzten und Patienten auf der Grundlage von Informationen aus bestehenden Broschüren entwickelt. Für den Test der Plattform wurden in 8 urologischen Kliniken 87 Patienten zur Teilnahme eingeladen. Die 56 Nutzer wurden 4 Wochen nach dem Login und 3 Monate nach dem Therapieentscheid online befragt, 48 Nutzer füllten beide Befragungen aus. Eingesetzte Instrumente waren die Preparation for Decision Making Scale (PDMS), die Decisional Conflict Scale (DCS) und die Decisional Regret Scale (DRS).
Ergebnisse und Diskussion: Die Nutzenden sind mit der Plattform sehr zufrieden und finden ihre Informationsbedürfnisse gut erfüllt. Sie zeigen 3 Monate nach dem Entscheid eine gute Vorbereitung auf die Entscheidung (MW PDMS 75, SD 23) und berichten über niedrigen Entscheidungskonflikt (MW DCS 9.6, SD 11) und kaum Bedauern über die Entscheidung (MW DRS 6.4, SD 9.6). Basierend auf diesen Erkenntnissen kann die Plattform zur weiteren Nutzung empfohlen werden.Background: Due to the multitude of therapy options the treatment decision after diagnosis of a localised prostate cancer is challenging. Compared to printed booklets, web based information technology offers more possibilities to tailor information to patients’ individual needs.
Objectives: To support the decision making process as well as the communication with patients we developed an online tutorial in a systematic process in the German speaking part of Switzerland and then tested it in a pilot study. The study investigated users’ satisfaction, the coverage of information needs, the preparation for decision making and the subjective quality of the decision.
Materials and methods: Based on already existing information material the online tutorial was developed in an iterative process using focus groups with patients and urologists. For the following evaluation in eight clinics a total of 87 patients were invited to access the platform and participate in the study. From these patients 56 used the tutorial and 48 answered both surveys (the first one 4 weeks after the first login and the second one 3 months after treatment decision). The surveys used the Preparation for Decision Making Scale (PDMS), the Decisional Conflict Scale (DCS), and the Decisional Regret Scale (DRS).
Results and Conclusion: Satisfaction with the tutorial is very high among patients with newly diagnosed localized prostate cancer. Users find their information needs sufficiently covered. Three months after the decision they felt that they were well prepared for the decision making (Mean PDMS 75, SD 23), they had low decisional conflict (Mean DCS 9.6, SD 11) and almost no decisional regret (Mean DRS 6.4, SD 9.6). Based on these findings the further use of the tutorial can be recommended
Triangulated Surfaces in Twistor Space: A Kinematical Set up for Open/Closed String Duality
We exploit the properties of the three-dimensional hyperbolic space to
discuss a simplicial setting for open/closed string duality based on (random)
Regge triangulations decorated with null twistorial fields. We explicitly show
that the twistorial N-points function, describing Dirichlet correlations over
the moduli space of open N-bordered genus g surfaces, is naturally mapped into
the Witten-Kontsevich intersection theory over the moduli space of N-pointed
closed Riemann surfaces of the same genus. We also discuss various aspects of
the geometrical setting which connects this model to PSL(2,C) Chern-Simons
theory.Comment: 35 pages, references added, slightly revised introductio
Pair Interaction Potentials of Colloids by Extrapolation of Confocal Microscopy Measurements of Collective Structure
A method for measuring the pair interaction potential between colloidal
particles by extrapolation measurement of collective structure to infinite
dilution is presented and explored using simulation and experiment. The method
is particularly well suited to systems in which the colloid is fluorescent and
refractive index matched with the solvent. The method involves characterizing
the potential of mean force between colloidal particles in suspension by
measurement of the radial distribution function using 3D direct visualization.
The potentials of mean force are extrapolated to infinite dilution to yield an
estimate of the pair interaction potential, . We use Monte Carlo (MC)
simulation to test and establish our methodology as well as to explore the
effects of polydispersity on the accuracy. We use poly-12-hydroxystearic
acid-stabilized poly(methyl methacrylate) (PHSA-PMMA) particles dispersed in
the solvent dioctyl phthalate (DOP) to test the method and assess its accuracy
for three different repulsive systems for which the range has been manipulated
by addition of electrolyte.Comment: 35 pages, 14 figure
A paradigm of open/closed duality: Liouville D-branes and the Kontsevich model
We argue that topological matrix models (matrix models of the Kontsevich
type) are examples of exact open/closed duality. The duality works at finite N
and for generic `t Hooft couplings. We consider in detail the paradigm of the
Kontsevich model for two-dimensional topological gravity. We demonstrate that
the Kontsevich model arises by topological localization of cubic open string
field theory on N stable branes. Our analysis is based on standard worldsheet
methods in the context of non-critical bosonic string theory. The stable branes
have Neumann (FZZT) boundary conditions in the Liouville direction. Several
generalizations are possible.Comment: v2: References added; a new section with generalization to non-zero
bulk cosmological constant; expanded discussion on topological localization;
added some comment
Dutch orthopedic thromboprophylaxis: a 5-year follow-up survey
Background and purpose Previous surveys in the Netherlands have revealed that guidelines regarding orthopedic thromboprophylaxis were not followed and that a wide variation in protocols exists. This survey was performed to assess the current use of thromboprophylactic modalities and to compare it with the results of a previous survey
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