Inhomogeneous Nuclear Spin Flips

We discuss a feedback mechanism between electronic states in a double quantum dot and the underlying nuclear spin bath. We analyze two pumping cycles for which this feedback provides a force for the Overhauser fields of the two dots to either equilibrate or diverge. Which of these effects is favored depends on the g-factor and Overhauser coupling constant A of the material. The strength of the effect increases with A/V_x, where V_x is the exchange matrix element, and also increases as the external magnetic field B_{ext} decreases.Comment: 5 pages, 4 figures (jpg

Magnetically induced chessboard pattern in the conductance of a Kondo quantum dot

We quantitatively describe the main features of the magnetically induced conductance modulation of a Kondo quantum dot -- or chessboard pattern -- in terms of a constant-interaction double quantum dot model. We show that the analogy with a double dot holds down to remarkably low magnetic fields. The analysis is extended by full 3D spin density functional calculations. Introducing an effective Kondo coupling parameter, the chessboard pattern is self-consistently computed as a function of magnetic field and electron number, which enables us to quantitatively explain our experimental data.Comment: 4 pages, 3 color figure

Fast sensing of double-dot charge arrangement and spin state with an rf sensor quantum dot

Single-shot measurement of the charge arrangement and spin state of a double quantum dot are reported, with measurement times down to ~ 100 ns. Sensing uses radio-frequency reflectometry of a proximal quantum dot in the Coulomb blockade regime. The sensor quantum dot is up to 30 times more sensitive than a comparable quantum point contact sensor, and yields three times greater signal to noise in rf single-shot measurements. Numerical modeling is qualitatively consistent with experiment and shows that the improved sensitivity of the sensor quantum dot results from reduced screening and lifetime broadening.Comment: related papers at http://marcuslab.harvard.ed

Dynamic Nuclear Polarization in Double Quantum Dots

We theoretically investigate the controlled dynamic polarization of lattice nuclear spins in GaAs double quantum dots containing two electrons. Three regimes of long-term dynamics are identified, including the build up of a large difference in the Overhauser fields across the dots, the saturation of the nuclear polarization process associated with formation of so-called "dark states," and the elimination of the difference field. We show that in the case of unequal dots, build up of difference fields generally accompanies the nuclear polarization process, whereas for nearly identical dots, build up of difference fields competes with polarization saturation in dark states. The elimination of the difference field does not, in general, correspond to a stable steady state of the polarization process.Comment: 4 pages, 2 figure

Intensive anticancer therapy in elderly patients – does it make sense? A case report

Anticancer therapy in elderly patients poses a great challenge for doctors since not all available therapeutic modalities can improve the wellbeing, alleviate symptoms or improve prognosis in this patient population. The paper presents a case of a 75-year-old woman diagnosed with advanced ovarian cancer who, despite advanced age, received intensive anticancer therapy, i.e. surgical treatment (modified posterior exenteration with the resection of pelvic peritoneum and tumor invasion in the diaphragmatic peritoneum along with its fragment, subtotal colectomy, resection of the omentum, spleen and gastric fragment along with the gastro-transverse ligament and an end ileostomy) as well as adjuvant chemotherapy. Severe complications occurring during treatment were not directly related to the therapy, but resulted from the lack of proper patient care in a home setting

Effect of confinement potential shape on exchange interaction in coupled quantum dots

Exchange interaction has been studied for electrons in coupled quantum dots (QD's) by a configuration interaction method using confinement potentials with different profiles. The confinement potential has been parametrized by a two-centre power-exponential function, which allows us to investigate various types of QD's described by either soft or hard potentials of different range. For the soft (Gaussian) confinement potential the exchange energy decreases with increasing interdot distance due to the decreasing interdot tunnelling. For the hard (rectangular-like) confinement potential we have found a non-monotonic behaviour of the exchange interaction as a function of distance between the confinement potential centres. In this case, the exchange interaction energy exhibits a pronounced maximum for the confinement potential profile which corresponds to the nanostructure composed of the small inner QD with a deep potential well embedded in the large outer QD with a shallow potential well. This effect results from the strong localization of electrons in the inner QD, which leads to the large singlet-triplet splitting. Implications of this finding for quantum logic operations have been discussed.Comment: 16 pages, including 11 figure

The longitudinal conductance of mesoscopic Hall samples with arbitrary disorder and periodic modulations

We use the Kubo-Landauer formalism to compute the longitudinal (two-terminal) conductance of a two dimensional electron system placed in a strong perpendicular magnetic field, and subjected to periodic modulations and/or disorder potentials. The scattering problem is recast as a set of inhomogeneous, coupled linear equations, allowing us to find the transmission probabilities from a finite-size system computation; the results are exact for non-interacting electrons. Our method fully accounts for the effects of the disorder and the periodic modulation, irrespective of their relative strength, as long as Landau level mixing is negligible. In particular, we focus on the interplay between the effects of the periodic modulation and those of the disorder. This appears to be the relevant regime to understand recent experiments [S. Melinte {\em et al}, Phys. Rev. Lett. {\bf 92}, 036802 (2004)], and our numerical results are in qualitative agreement with these experimental results. The numerical techniques we develop can be generalized straightforwardly to many-terminal geometries, as well as other multi-channel scattering problems.Comment: 13 pages, 11 figure

Chaos in Quantum Dots: Dynamical Modulation of Coulomb Blockade Peak Heights

The electrostatic energy of an additional electron on a conducting grain blocks the flow of current through the grain, an effect known as the Coulomb blockade. Current can flow only if two charge states of the grain have the same energy; in this case the conductance has a peak. In a small grain with quantized electron states, referred to as a quantum dot, the magnitude of the conductance peak is directly related to the magnitude of the wavefunction near the contacts to the dot. Since dots are generally irregular in shape, the dynamics of the electrons is chaotic, and the characteristics of Coulomb blockade peaks reflects those of wavefunctions in chaotic systems. Previously, a statistical theory for the peaks was derived by assuming these wavefunctions to be completely random. Here we show that the specific internal dynamics of the dot, even though it is chaotic, modulates the peaks: because all systems have short-time features, chaos is not equivalent to randomness. Semiclassical results are derived for both chaotic and integrable dots, which are surprisingly similar, and compared to numerical calculations. We argue that this modulation, though unappreciated, has already been seen in experiments.Comment: 4 pages, 3 postscript figs included (2 color), uses epsf.st

Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia

Human motor activity has a robust, intrinsic fractal structure with similar patterns from minutes to hours. The fractal activity patterns appear to be physiologically important because the patterns persist under different environmental conditions but are significantly altered/reduced with aging and Alzheimer's disease (AD). Here, we report that dementia patients, known to have disrupted circadian rhythmicity, also have disrupted fractal activity patterns and that the disruption is more pronounced in patients with more amyloid plaques (a marker of AD severity). Moreover, the degree of fractal activity disruption is strongly associated with vasopressinergic and neurotensinergic neurons (two major circadian neurotransmitters) in postmortem suprachiasmatic nucleus (SCN), and can better predict changes of the two neurotransmitters than traditional circadian measures. These findings suggest that the SCN impacts human activity regulation at multiple time scales and that disrupted fractal activity may serve as a non-invasive biomarker of SCN neurodegeneration in dementia