6,130 research outputs found
Anomalous Properties of Sub-10-nm Magnetic Tunneling Junctions
Magnetic Logic Devices have the advantage of non-volatility, radiation hardness, scalability down to the sub-10nm range, and three-dimensional (3D) integration capability. Despite these advantages, magnetic applications for information processing remain limited. The main stumbling block is the high energy required to switch information states in spin-based devices. Recently, the spin transfer torque (STT) effect has been introduced as a promising solution. STT based magnetic tunneling junctions (MTJs), use a spin polarized electric current to switch magnetic states. They are theorized to bring the switching energy down substantially. However, the switching current density remains in the order of 1 MA/cm2 in current STT-MTJ devices, with the smallest device reported to date around 10nm. This current density remains inadequately high for enabling a wide range of information processing applications. For this technology to be competitive in the near future it is critical to show that it could be favorably scaled into the sub-10-nm range. This is an intriguing size range that currently remains unexplored. Nanomagnetic devices may display promising characteristics that can make them superior to their semiconductor counterparts. Below 10nm the spin physics from the vii surface become dominate versus those due to volume. The goal is to understand the size dependence versus the switching current
\u27Whence This Evil?\u27 A Critical Assessment of (Anti)Theodicy and Innocent Suffering in Lamentations 3
Recent scholarship on Lamentations has focused on the voice of Daughter Zion in chapters 1-2. Arguing that the frank protests constitute an antitheodicy, interpreters have placed these poems in opposition to the voice of the man in Lam 3, specifically 3:21-42. This Wisdom-like, paraenetic section is seen to put forth a theodicy, counseling penitent acceptance of God\u27s righteous judgment. The present study argues instead that, when incorporated into the rhetorical movement of Lam 3 as a whole, 3:21-42 instead constitutes an antitheodicy consonant with Lam 1-2. It is proposed that Lamentations manipulates the expected theodicy solution until it has been ironized as an ethically deficient foil, problematizing the facile justifications offered for Jerusalem\u27s plight. This is accomplished through close exegesis of Lam 3 and utilizing Mikhail Bakhtin\u27s concepts of dialogism and double voicing. Theological implications are offered in the final chapter
Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p
During mating, budding yeast cells reorient growth toward the highest concentration of pheromone. Bni1p, a formin homologue, is required for this polarized growth by facilitating cortical actin cable assembly. Fus3p, a pheromone-activated MAP kinase, is required for pheromone signaling and cell fusion. We show that Fus3p phosphorylates Bni1p in vitro, and phosphorylation of Bni1p in vivo during the pheromone response is dependent on Fus3p. fus3 mutants exhibited multiple phenotypes similar to bni1 mutants, including defects in actin and cell polarization, as well as Kar9p and cytoplasmic microtubule localization. Disruption of the interaction between Fus3p and the receptor-associated Gα subunit caused similar mutant phenotypes. After pheromone treatment, Bni1p-GFP and Spa2p failed to localize to the cortex of fus3 mutants, and cell wall growth became completely unpolarized. Bni1p overexpression suppressed the actin assembly, cell polarization, and cell fusion defects. These data suggest a model wherein activated Fus3p is recruited back to the cortex, where it activates Bni1p to promote polarization and cell fusion.</jats:p
“Get those voices at the table!”: Interview with Deborah Stone
__Abstract__
Deborah Stone’s work on political reasoning, storytelling and metaphors has been a
longstanding contribution to the development of public administration, political and policy
sciences. In her book Policy Paradox and Political Reason published in 1988, she focuses
on policy and politics as cultural bargaining over values and ideas, instead of a rational
process of decision-making. In addition to this book, which was retitled Policy Paradox,
The Art of Political Decision Making in later editions, she has published widely on societal
paradoxes, political reasoning and professional dilemmas in many aspects of social policy.
The newest edition (published in 2012 and called the third edition, but really the fourth)
incorporates major revisions to the literature, theories and policy illustrations, including
more examples from international relations and countries besides the USA.
Due to this key contribution and the longstanding relevance of her book, we talked with
Deborah Stone in Vienna on 5 July 2013. We had a dialogue about this book, her theoretical
ideas and how policy sciences could improve in the future
Aspectos prácticos de la adopciĂłn de un esquema de metas de inflaciĂłn en economĂas emergentes: Posibles implicancias para el PerĂş
ClasificaciĂłn JEL:
Quantifying the effect of interannual ocean variability on the attribution of extreme climate events to human influence
In recent years, the climate change research community has become highly
interested in describing the anthropogenic influence on extreme weather events,
commonly termed "event attribution." Limitations in the observational record
and in computational resources motivate the use of uncoupled,
atmosphere/land-only climate models with prescribed ocean conditions run over a
short period, leading up to and including an event of interest. In this
approach, large ensembles of high-resolution simulations can be generated under
factual observed conditions and counterfactual conditions that might have been
observed in the absence of human interference; these can be used to estimate
the change in probability of the given event due to anthropogenic influence.
However, using a prescribed ocean state ignores the possibility that estimates
of attributable risk might be a function of the ocean state. Thus, the
uncertainty in attributable risk is likely underestimated, implying an
over-confidence in anthropogenic influence.
In this work, we estimate the year-to-year variability in calculations of the
anthropogenic contribution to extreme weather based on large ensembles of
atmospheric model simulations. Our results both quantify the magnitude of
year-to-year variability and categorize the degree to which conclusions of
attributable risk are qualitatively affected. The methodology is illustrated by
exploring extreme temperature and precipitation events for the northwest coast
of South America and northern-central Siberia; we also provides results for
regions around the globe. While it remains preferable to perform a full
multi-year analysis, the results presented here can serve as an indication of
where and when attribution researchers should be concerned about the use of
atmosphere-only simulations
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