Deep Radio Imaging of Globular Clusters and the Cluster Pulsar Population

We have obtained deep multifrequency radio observations of seven globular clusters using the Very Large Array and the Australia Telescope Compact Array. Five of these, NGC 6440, NGC 6539, NGC 6544, NGC 6624 and Terzan 5 had previously been detected in a shallower survey for steep spectrum radio sources in globular clusters (Fruchter and Goss 1990). The sixth, the rich globular cluster, Liller 1, had heretofore been undetected in the radio, and the seventh, 47 Tucanae, was not included in our original survey. High resolution 6 and 20 cm images of three of the clusters, NGC 6440, NGC 6539, NGC 6624 reveal only point sources coincident with pulsars which have been discovered subsequent to our first imaging survey. 21 and 18 cm images reveal several point sources within a few core-radii of the center of 47 Tuc. Two of these are identified pulsars, and a third, which is both variable and has a steep spectrum, is also most likely a pulsar previously identified by a pulsed survey. However, the 6, 20 and 90 cm images of NGC 6544, Liller 1 and Terzan 5 display strong steep-spectrum emission which cannot be associated with known pulsars. The image of the rich cluster Terzan 5 displays numerous point sources within $30''$, or 4 core radii of the cluster center. The density of these objects rises rapidly toward the core, where an elongated region of emission is found. The brightest individual sources, as well as the extended emission, possess the steep spectra expected of pulsars. Furthermore, the flux distribution of the sources agrees well with the standard pulsar luminosity function. The total luminosity and number of objects observed suggest that Terzan 5 contains more pulsars than any other Galactic globular cluster.Comment: 33 pages, 6 Postscript figures; Accepted for publication in the Astrophysical Journal; abstract abridged. PDF version also available at http://nemesis.stsci.edu/~fruchter/fg99/fg99.pd

The Halo Beaming Model for Gamma-Ray Bursts

We consider a model for gamma-ray bursts (GRBs) from high-velocity neutron stars in the galactic halo. In this model, bursters are born in the galactic disk with large recoil velocities V_r, and GRBs are beamed to within emission cones of half-angle \phi centered on V_r. We describe scenarios for magnetically -channeled GRBs that have such beaming characteristics. We then make detailed comparisons of this halo beaming model (HBM) to BATSE and PVO data for GRB intensity & angular position distributions. Acceptable fits to observations of over 1000 bursts are obtained for \phi = 15 - 30 degrees and for a BATSE sampling depth ~ 180 kpc. Present data favor a truly isotropic (cosmological) model over the HBM, but not by a statistically compelling margin. Bursters born in nearby external galaxies, such as M31, are almost entirely undetectable in the HBM because of misdirected beaming. We analyze several refinements of the basic HBM: gamma-ray intensities that vary with angle from the beam axis; non-standard-candle GRB luminosity functions; and models including a subset of bursters that do not escape from the galaxy. We also discuss the energy budgets for the bursters, the origins of their recoils, and the physics of burst beaming and alignment. One possible physical model is based on the magnetar model of soft gamma repeaters (SGRs). Empirical bounds on the rate of formation and peculiar velocities of SGRs imply that there exist ~ 10^4 to ~ 10^7 aged SGRs in the galactic halo within a distance of 100 kpc. The HBM gives an acceptable fit to observations only if it satisfies certain conditions (e.g. \phi ~ 20 deg) which are possible, but for which there exist no clear & compelling theoretical justifications. The cosmological burster hypothesis is more generic and thus more attractive in this sense. (Abbreviated Abstract).Comment: ApJ accepted, 9 figures, AASTE

G328.4+0.2 : A large and luminous Crab-like supernova remnant

We report on radio continuum and HI observations of the radio source G328.4+0.2 using the Australia Telescope Compact Array. Our results confirm G328.4+0.2 to be a filled-center nebula with no surrounding shell, showing significant linear polarization and an almost flat spectral index. These results lead us to conclude that G328.4+0.2 is a Crab-like, or ``plerionic'', supernova remnant (SNR), presumably powered by an unseen central pulsar. HI absorption towards G328.4+0.2 puts a lower limit on its distance of 17.4 +/- 0.9 kpc, making it the largest (D=25 pc) and most luminous (L_R = 3e35 erg/s) Crab-like SNR in the Galaxy. We infer G328.4+0.2 to be significantly older than the Crab Nebula, but powered by a pulsar which is fast spinning (P<20 ms) and which has a comparatively low magnetic field (B<1e12 G). We propose G328.4+0.2, G74.9+1.2 and N157B as a distinct group of large-diameter, high-luminosity Crab-like SNRs, all powered by fast-spinning low-field pulsars.Comment: 7 pages, 3 embedded EPS figures, uses emulateapj.sty. Accepted to ApJ. Abstract corrected so that distance is now in kpc, not pc

Thin accretion disc with a corona in a central magnetic field

We study the steady-state structure of an accretion disc with a corona surrounding a central, rotating, magnetized star. We assume that the magneto-rotational instability is the dominant mechanism of angular momentum transport inside the disc and is responsible for producing magnetic tubes above the disc. In our model, a fraction of the dissipated energy inside the disc is transported to the corona via these magnetic tubes. This energy exchange from the disc to the corona which depends on the disc physical properties is modified because of the magnetic interaction between the stellar magnetic field and the accretion disc. According to our fully analytical solutions for such a system, the existence of a corona not only increases the surface density but reduces the temperature of the accretion disc. Also, the presence of a corona enhances the ratio of gas pressure to the total pressure. Our solutions show that when the strength of the magnetic field of the central neutron star is large or the star is rotating fast enough, profiles of the physical variables of the disc significantly modify due to the existence of a corona.Comment: Accepted for publication in Astrophysics & Space Scienc

Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets

Imaging- and therapeutic targets in neoplastic and musculoskeletal inflammatory diseas

The influence of Mechanical bowel preparation in elective colorectal surgery for diverticulitis

Background: Mechanical bowel preparation (MBP) has been shown to have no influence on the incidenc

Barriers, facilitators, and other factors associated with health behaviors in childhood, adolescent, and young adult cancer survivors: A systematic review

\ua9 2024 The Author(s). Cancer Medicine published by John Wiley &amp; Sons Ltd.Background: Healthy behaviors are paramount in preventing long-term adverse health outcomes in childhood, adolescent, and young adult (CAYA) cancer survivors. We systematically reviewed and synthesized existing literature on barriers, facilitators, and other factors associated with health behaviors in this population. Methods: MEDLINE and PsycInfo were searched for qualitative and quantitative studies including survivors aged 16–50 years at study, a cancer diagnosis ≤25 years and ≥2 years post diagnosis. Health behaviors included physical activity, smoking, diet, alcohol consumption, sun exposure, and a combination of these behaviors (defined as health behaviors in general). Results: Barriers, facilitators, and other factors reported in ≥2 two studies were considered relevant. Out of 4529 studies, 27 were included (n = 31,905 participants). Physical activity was the most frequently examined behavior (n = 12 studies), followed by smoking (n = 7), diet (n = 7), alcohol (n = 4), sun exposure (n = 4), and health behavior in general (n = 4). Relevant barriers to physical activity were fatigue, lack of motivation, time constraints, and current smoking. Relevant facilitators were perceived health benefits and motivation. Influence of the social environment and poor mental health were associated with more smoking, while increased energy was associated with less smoking. No relevant barriers and facilitators were identified for diet, alcohol consumption, and sun exposure. Barriers to healthy behavior in general were unmet information needs and time constraints whereas lifestyle advice, information, and discussions with a healthcare professional facilitated healthy behavior in general. Concerning other factors, women were more likely to be physically inactive, but less likely to drink alcohol and more likely to comply with sun protection recommendations than men. Higher education was associated with more physical activity, and lower education with more smoking. Conclusion: This knowledge can be used as a starting point to develop health behavior interventions, inform lifestyle coaches, and increase awareness among healthcare providers regarding which survivors are most at risk of unhealthy behaviors

A multicenter randomized clinical trial investigating the cost-effectiveness of treatment strategies with or without antibiotics for uncomplicated acute diverticulitis (DIABOLO trial)

Background. Conservative treatment of uncomplicated or mild diverticulitis usually includes antibiotic therapy. It is, however, uncertain whether patients with acute diverticulitis indeed benefit from antibiotics. In most guidelines issued by professional organizations antibiotics are considered mandatory in the treatment of mild diverticulitis. This advice lacks evidence and is merely based on experts' opinion. Adverse effects of the use of antibiotics are well known, including allergic reactions, development of bacterial resistance to antibiotics and other side-effects. Methods. A randomized multicenter pragmatic clinical trial comparin