70 research outputs found

    Should You Use a Fungicidal Seed Treatment on Low-Quality Soybean Seed?

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    With this year’s harvest of soybeans delayed beyond what is considered an ideal window of time, the opportunity for diseases to infect seed pods and in some instances, to the seed itself, was greatly increased. Across the state and the north central region, seed suppliers have reported that this year’s crops of seed soybean are frequently testing positive for the Diaporthe fungus (Phomopsis seed decay), which is resulting in lower than normal germination rates of seed. Seed decay is characterized by cracked, shriveled seed with white chalk-colored mold on the seed surface

    2019 Soybean Foliar Fungicide Trials Show Decreasing Efficiency in QoI Class

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    Iowa State University researchers recently published their annual fungicide trial data for soybeans in 2019, revealing a continued decline in efficiency among the quinone outside inhibitors (QoI) class of fungicides in preventing foliar diseases in soybeans

    Protective effect and economic impact of insecticide application methods on barley.

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    Avalia o efeito protetor de diferentes formas de aplicação de inseticida sobre a transmissão do nanismo amarelo em cultivares de cevada, bem como determina os custos de produção e o lucro líquido destes manejos. Os experimentos foram realizados durante as safras 2011 e 2012, tendo-se utilizado os seguintes manejos nas parcelas principais: T1, tratamento de sementes com inseticida (TS) + inseticida na parte aérea aplicado quinzenalmente; T2, apenas TS; T3, inseticida aplicado à parte aérea, quando foi atingido o nível de controle de afídeos (NC); T4, sem inseticida; e T5, TS + inseticida na parte aérea, quando o NC foi atingido. As subparcelas foram constituídas de diferentes cultivares de cevada: BRS Cauê, BRS Brau e MN 6021. Foram utilizados os inseticidas lambda‑cialotrina (piretroide) e thiametoxam (neonicotinoide). Houve diferenças no índice de doença do nanismo amarelo em ambas as safras para os diferentes manejos, enquanto o dano ao rendimento de grãos foi influenciado pelo ano e pela população de afídeos. Os custos de produção e lucro líquido diferiram entre os tratamentos. Constatou-se que o tratamento de sementes com inseticida é suficiente para reduzir a epidemia do nanismo‑amarelo em anos com baixa pressão populacional de afídeos; porém, em anos com maiores populações, a aplicação de inseticida à parte aérea também se torna necessária

    A new model for the characterization of infection risk in gunshot injuries:Technology, principal consideration and clinical implementation

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    <p>Abstract</p> <p>Introduction</p> <p>The extent of wound contamination in gunshot injuries is still a topic of controversial debate. The purpose of the present study is to develop a model that illustrates the contamination of wounds with exogenous particles along the bullet path.</p> <p>Material and methods</p> <p>To simulate bacteria, radio-opaque barium titanate (3-6 μm in diameter) was atomized in a dust chamber. Full metal jacket or soft point bullets caliber .222 (n = 12, v<sub>0 </sub>= 1096 m/s) were fired through the chamber into a gelatin block directly behind it. After that, the gelatin block underwent multi-slice CT in order to analyze the permanent and temporary wound cavity.</p> <p>Results</p> <p>The permanent cavity caused by both types of projectiles showed deposits of barium titanate distributed over the entire bullet path. Full metal jacket bullets left only few traces of barium titanate in the temporary cavity. In contrast, the soft point bullets disintegrated completely, and barium titanate covered the entire wound cavity.</p> <p>Discussion</p> <p>Deep penetration of potential exogenous bacteria can be simulated easily and reproducibly with barium titanate particles shot into a gelatin block. Additionally, this procedure permits conclusions to be drawn about the distribution of possible contaminants and thus can yield essential findings in terms of necessary therapeutic procedures.</p

    Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development

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    Vinflunine, the most recent Vinca alkaloid in clinical development, demonstrated superior antitumour activity to other Vincas in preclinical tumour models. This study aimed to define its molecular mechanisms of cell killing in both parental sensitive and vinflunine-resistant P388 leukaemia cells. Vinflunine treatment of these cells resulted in apoptosis characterized by DNA fragmentation and proteolytic cleavage of poly-(ADP-ribose) polymerase. Apoptosis-inducing concentrations of vinflunine caused c-Jun N-terminal kinase 1 stimulation, as well as caspases-3/7 activation. This activation of caspases and the induction of apoptosis could be inhibited by the caspase inhibitor acetyl-Asp-Glu-Val-Asp-aldehyde. Interestingly, the apoptosis signal triggered by vinflunine in these P388 cells was not mediated through Bcl-2 phosphorylation. In addition, when vinflunine resistance was developed in P388 cells, it was associated with resistance to vinflunine-induced apoptosis, as reflected by a loss of capacity to induce DNA fragmentation and PARP degradation, and characterized by increased levels of Bcl-2 and Bfl-1/A1. Therefore, these data indirectly implicate Bcl-2 and Bfl-1/A1 in vinflunine-induced cell death mechanisms

    Situationism and the recuperation of an ideology in the era of Trump, fake news and post-truth politics

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    As a variant ideology based on libertarian Marxism, the philosophy of situationism failed to achieve widespread popularity beyond a relatively brief timeframe between the late 1950s and early 1970s. Despite this short-lived period of ascendency, the impact of Situationist concepts such as psychogeography, recuperation and the Spectacle have continued to play a role in the ongoing study of how reality is constructed in a system of advanced capitalism. Situationism’s concern with the perception of reality as shaped by the mass media is of particular significance in the context of contemporary politics that has been dubbed the ‘post-truth era’. The disavowal of the mass media by US President Donald Trump may give the impression of a Situationist approach that rejects the impact of such reality-shaping tools, yet a closer inspection of his actions suggests that Trump himself is responsible for the construction of a neo-Spectacle in which the recuperation of anti-establishment sentiment provides the basis for the reconsolidation of the position held by the capitalist elite within American society
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