Economic pause - some perspective and interpretation

Economic conditions

Mixed layer temperature response to the southern annular mode: Mechanisms and model representation

Previous studies have shown that simulated sea surface temperature (SST) responses to the southern annular mode (SAM) in phase 3 of the Coupled Model Intercomparison Project (CMIP3) climate models compare poorly to the observed response. The reasons behind these model inaccuracies are explored. The ocean mixed layer heat budget is examined in four of the CMIP3 models and by using observations- reanalyses. The SST response to the SAM is predominantly driven by sensible and latent heat flux and Ekman heat transport anomalies. The radiative heat fluxes play a lesser but nonnegligible role. Errors in the simulated SST responses are traced back to deficiencies in the atmospheric response to the SAM. The models exaggerate the surface wind response to the SAM leading to large unrealistic Ekman transport anomalies. During the positive phase of the SAM, this results in excessive simulated cooling in the 40°-65°S latitudes. Problems with the simulated wind stress responses, which relate partly to errors in the simulated winds themselves and partly to the transfer coefficients used in the models, are a key cause of the errors in the SST response. In the central Pacific sector (90°-150°W), errors arise because the simulated SAM is too zonally symmetric. Substantial errors in the net shortwave radiation are also found, resulting from a poor repre- sentation of the changes in cloud cover associated with the SAM. The problems in the simulated SST re- sponses shown by this study are comparable to deficiencies previously identified in the CMIP3 multimodel mean. Therefore, it is likely that the deficiencies identified here are common to other climate models

Differences in both prevalence and titre of specific immunoglobulin E among children with asthma in affluent and poor communities within a large town in Ghana.

Background Reports from several African countries have noted an increasing prevalence of asthma in areas of extensive urbanization. Objective To investigate the relevance of allergen-specific sensitization and body mass index (BMI) to asthma/wheezing and exercise-induced bronchospasm (EIB) among children from affluent and poorer communities within a large town in Ghana. Methods Children with physician-diagnosed asthma and/or current wheezing aged 9-16 years (n=99; cases) from three schools with differing socio-economic backgrounds [urban affluent (UA), urban poor (UP) or suburban/rural (SR)] were recruited from a cross-sectional study (n=1848) in Kumasi, Ghana, and matched according to age, sex and area of residence with non-asthmatic/non-wheezy controls. We assayed sera for IgE antibodies to mite, cat, dog, cockroach, Ascaris and galactose-α-1,3-galactose. Results Children from the UA school had the lowest total serum IgE. However, cases from the UA school had a higher prevalence and mean titre of sIgE to mite (71.4%, 21.2IU/mL) when compared with controls (14.3%, 0.8IU/mL) or cases from UP (30%, 0.8IU/mL) and SR community (47.8%, 1.6IU/mL). While similar findings were observed with EIB in the whole population, among cases there was no difference in IgE antibody prevalence or titre between children with or without EIB. BMI was higher among UA children with and without asthma; in UP and SR communities, children with EIB (n=14) had a significantly higher BMI compared with children with asthma/wheezing without EIB (n=38) (18.2 vs. 16.4, respectively, P<0.01). Conclusions and Clinical Relevance In the relatively affluent school, asthma/wheezing and EIB were associated with high titre IgE antibodies to mite, decreased total IgE, and increased BMI. This contrasted with children in the urban poor school and suggests that changes relevant to a Western model of childhood asthma can occur within a short geographical distance within a large city in Africa. © 2011 Blackwell Publishing Ltd

Natural resource data analysis: Finding comfort with computers

For the past six years Michigan State University Department of Forestry has offered a course, Natural Resource Data Analysis, that has evolved as computer skills, there are three principle objectives in the course: identifying a natural resource problem and obtaining relevant data; conducting an objective, quantitative analysis of data; and presenting the analysis in a way that is clear to a non-technical audience. The course consists of a combined lecture/lab where fundamental concepts oral and written communication, quantitative analysis, and spatial analysis/cartography are introduced and a hands-on lab where students practice specific computer and analytic skills. The ultimate course objective is the presentation of an analysis of a natural resource problem via World Wide Web pages, a written report and an oral, computer-assisted presentation

Effect of the Coriolis Force on the Hydrodynamics of Colliding Wind Binaries

Using fully three-dimensional hydrodynamic simulations, we investigate the effect of the Coriolis force on the hydrodynamic and observable properties of colliding wind binary systems. To make the calculations tractable, we assume adiabatic, constant velocity winds. The neglect of radiative driving, gravitational deceleration, and cooling limit the application of our models to real systems. However, these assumptions allow us to isolate the effect of the Coriolis force, and by simplifying the calculations, allow us to use a higher resolution (up to 640^3) and to conduct a larger survey of parameter space. We study the dynamics of collidng winds with equal mass loss rates and velocities emanating from equal mass stars on circular orbits, with a range of values for the ratio of the wind to orbital velocity. We also study the dynamics of winds from stars on elliptical orbits and with unequal strength winds. Orbital motion of the stars sweeps the shocked wind gas into an Archimedean spiral, with asymmetric shock strengths and therefore unequal postshock temperatures and densities in the leading and trailing edges of the spiral. We observe the Kelvin-Helmholtz instability at the contact surface between the shocked winds in systems with orbital motion even when the winds are identical. The change in shock strengths caused by orbital motion increases the volume of X-ray emitting post-shock gas with T > 0.59 keV by 63% for a typical system as the ratio of wind velocity to orbital velocity decreases to V_w/V_o = 2.5. This causes increased free-free emission from systems with shorter orbital periods and an altered time-dependence of the wind attenuation. We comment on the importance of the effects of orbital motion on the observable properties of colliding wind binaries.Comment: 12 pages, 17 figures, accepted for publication in Ap

Multiwavelength observations of the Be/X-ray binary 4U1145-619

We report optical and infrared observations of the massive X-ray binary system 4U1145-619 (V801 Cen) which show that the circumstellar disc of the Be star component is in decline. Infrared J,H,K,L magnitudes of V801Cen have been monitored from 1993 March to 1996 April. H alpha spectra have been obtained throughout the same period. We find that both the infrared excess and the Balmer emission have been in decline throughout the period of observations. A 13 year optical and X-ray history of the source has been collated, revealing a possible correlation between the optical and X-ray activity. In addition, we have used u,v,b,y,beta indices, corrected for both circumstellar and interstellar effects, to calculate the physical parameters of the underlying B star.Comment: 8 pages postscript. Accepted by MNRA

Peripheral neuropathy secondary to a ‘domino’ liver transplant: a case report

Background: Peripheral neuropathy caused by amyloidosis is one of the well-recognised sequelae of mutations in the transthyretin gene (TTR).// Case presentation: We describe a case of peripheral neuropathy in a White British 74 year old man with wild-type TTR, 8 years following receipt of a ‘domino’ liver transplant (from a donor with a TTR mutation). The clinical phenotype and neurophysiology, coupled with presence of ATTR amyloid deposits on fat biopsy, established the diagnosis of ATTR amyloid neuropathy, as a consequence of receipt of a variant-TTR secreting liver. A nerve biopsy was not clinically appropriate for this patient. Such cases are rare since recipients of such livers are typically restricted to people whose natural lifespan is unlikely to stretch into the anticipated symptomatic period of ATTR amyloidosis. However, novel “gene silencing” therapeutics are now available which can dramatically alter the course of this disorder, by reducing the proportion of abnormal proteins.// Conclusions: This represents a rare but predictable iatrogenic side effect, and doctors should be aware of this eventuality occurring in a shorter time span than previously anticipated

Comparative Winter Habitat Use and Associations among Herbivores in the High Arctic

We studied winter habitat use and interspecific associations among large- and medium-sized herbivores on southeastern Victoria Island, Arctic Canada, by documenting the deposition of feces in relation to vegetation. Associations between ptarmigan (Lagopus spp.), arctic hares (Lepus arcticus), caribou (Rangifer tarandus), and muskoxen (Ovibos moschatus) were assessed using the Jaccard Index (JI) and chi² at two scales, i.e., with 1 m² and 1 ha as sampling units. JI values for species pairs were greater at the larger scale, but chi² revealed significant (positive) associations only at the smaller scale and only between arctic hares and caribou and between arctic hares and ptarmigan. Comparative use of habitats was described with respect to vegetation by canonical correspondence analysis (CCA). Ptarmigan and muskoxen were most strongly correlated with lowland vegetation and caribou with upland vegetation; arctic hares were intermediate. CCA also indicated rather wide separation in the multivariate space, further suggesting distinct patterns of habitat use. The results imply that these species were segregated in their use of resources in this High Arctic environment.On a étudié l'utilisation de l'habitat hivernal et les associations biotiques parmi les grands et moyens herbivores du sud-est de l'île Victoria située dans l'Arctique canadien, en étudiant l'emplacement des crottes par rapport à la végétation. À l'aide de l'index Jaccard (IJ) et de chi² à deux échelles (c.-à-d. en prenant 1 m² et 1 ha comme unités d'échantillonnage), on a évalué les associations entre le lagopède (Lagopus spp), le lièvre arctique (Lepus arcticus), le caribou (Rangifer tarandus) et le boeuf musqué (Ovibos moschatus). Les valeurs de IJ pour les paires d'espèces étaient plus élevées à grande échelle, mais chi² ne montrait des associations notables (positives) qu'à petite échelle et seulement entre le lièvre arctique et le caribou ainsi qu'entre le lièvre arctique et le lagopède. On a décrit l'utilisation comparative des habitats en rapport avec la végétation par analyse de correspondance canonique (ACC). Le lagopède et le boeuf musqué étaient corrélés le plus fortement avec la végétation des basses-terres et le caribou avec celle des hautes-terres; le lièvre arctique se situait au milieu. L'ACC montrait aussi une séparation relativement importante dans l'espace à plusieurs variables, ce qui laisse suggérer des modèles distincts d'utilisation de l'habitat. Les résultats indiqueraient qu'il existait pour ces espèces une ségrégation dans l'utilisation des ressources au sein de cet environnement extrême-arctique

Peripheral neuropathy secondary to a ‘domino’ liver transplant:a case report

Abstract Background Peripheral neuropathy caused by amyloidosis is one of the well-recognised sequelae of mutations in the transthyretin gene (TTR). Case presentation We describe a case of peripheral neuropathy in a White British 74 year old man with wild-type TTR, 8 years following receipt of a ‘domino’ liver transplant (from a donor with a TTR mutation). The clinical phenotype and neurophysiology, coupled with presence of ATTR amyloid deposits on fat biopsy, established the diagnosis of ATTR amyloid neuropathy, as a consequence of receipt of a variant-TTR secreting liver. A nerve biopsy was not clinically appropriate for this patient. Such cases are rare since recipients of such livers are typically restricted to people whose natural lifespan is unlikely to stretch into the anticipated symptomatic period of ATTR amyloidosis. However, novel “gene silencing” therapeutics are now available which can dramatically alter the course of this disorder, by reducing the proportion of abnormal proteins. Conclusions This represents a rare but predictable iatrogenic side effect, and doctors should be aware of this eventuality occurring in a shorter time span than previously anticipated