20141220 Database for PLoS ONE Manuscript

20141220 Database for PLoS ONE Manuscrip

Outcome measure results.

<p>Outcome measure results.</p

Scenario B.

<p>The median was calculated using teams performing the outcome measure (teams not performing the outcome measure are represented by open circles placed at the time when their scenario was stopped).</p

Scenario C.

<p>The median was calculated using teams performing the outcome measure (teams not performing the outcome measure are represented by open circles placed at the time when their scenario was stopped).</p

Scenario D.

<p>The median was calculated using teams performing the outcome measure (teams not performing the outcome measure are represented by open circles placed at the time when their scenario was stopped).</p

Scenario A.

<p>The median was calculated using teams performing the outcome measure (teams not performing the outcome measure are represented by open circles placed at the time when their scenario was stopped).</p

Additional file 2: of Acute effects of reducing sitting time in adolescents: a randomized cross-over study

Condition B: A ‘reduced sitting’ school day schedule. Description: A table demonstrating the protocol used to guide participants through the first condition: a ‘reduced sitting’ school day. (DOCX 12 kb

Additional file 1: of Expert consensus on re-irradiation for recurrent glioma

Survey Monkey. (PDF 2056 kb

Additional file 1: of Overweight modifies the association between long-term ambient air pollution and prehypertension in Chinese adults: the 33 Communities Chinese Health Study

Outlining baseline characteristics of the study population, air pollutants exposures, and additional modeling details. Supplementary methods. explanation of the air pollution data. Table S1. Characteristics of the study participants and non-participants. Table S2. Three-year average concentrations of air pollutants and area-level GDP and PD in 11 districts. Table S3. Pair-wise correlations of air pollutants. Table S4. Age- and sex-adjusted prevalence rate of prehypertension in relation to categories of air pollutants concentrations and BMI. Table S5. Associations between air pollutants and blood pressures in two BMI categories after excluding participants who were underweight. Table S6. Associations between air pollutants and blood pressures in two BMI categories after excluding hypotensive participants. Table S7. Associations between air pollutants and blood pressures in two BMI categories after excluding participants with diabetes mellitus. (DOCX 61 kb

Fragment-Based Discovery of 6‑Azaindazoles As Inhibitors of Bacterial DNA Ligase

Herein we describe the application of fragment-based drug design to bacterial DNA ligase. X-ray crystallography was used to guide structure-based optimization of a fragment-screening hit to give novel, nanomolar, AMP-competitive inhibitors. The lead compound <b>13</b> showed antibacterial activity across a range of pathogens. Data to demonstrate mode of action was provided using a strain of <i>S. aureus</i>, engineered to overexpress DNA ligase