838 research outputs found

    Description and Status of the DC Lightning Mapping Array

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    The DC Lightning Mapping Array (DC LMA) centered on the Washington, DC metro region has been in operation since 2006. During that time the DC LMA has provided real time data to regional National Weather Service (NSF) Sterling, VA forecast office for operations support and the NOAA Meteorological Development Laboratory (MDL) for new product development and assessment. Data from this network (as well as other from other LMA systems) are now being used to create proxy Geostationary Lightning Mapper (GLM) data sets for GOES-R risk reduction and algorithm development activities. In addition, since spring 2009 data are provided to the Storm Prediction Center in support of Hazardous Weather Testbed and GOES-R Proving Ground activities during the Spring Program. Description, status and plans will be discussed

    Eliurus majori complex

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    21 p. : ill. (1 col.), 1 map ; 26 cm.Includes bibliographical references (p. 19-20).A new species of Eliurus, E. danieli (Nesomyidae: Nesomyinae), is described from the Parc National de l'Isalo in south-central Madagascar. Although geographically intermediate to eastern and western forms, diagnostic traits convincingly relate the new species to E. majori and E. penicillatus, forms distributed primarily in eastern humid forest; it is morphometrically most similar to E. penicillatus. In view of the increase in number of Eliurus species (11 now described), discussion is devoted to emerging species associations (5 are identified) and to taxonomic and distributional problems introduced by the accumulation of larger series and new localities over the past decade

    The influence of meridional ice transport on Europa’s ocean stratification and heat content

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    Jupiter’s moon Europa likely hosts a saltwater ocean beneath its icy surface. Geothermal heating and rotating convection in the ocean may drive a global overturning circulation that redistributes heat vertically and meridionally, preferentially warming the ice shell at the equator. Here we assess the previously unconstrained influence of ocean‐ice coupling on Europa’s ocean stratification and heat transport. We demonstrate that a relatively fresh layer can form at the ice‐ocean interface due to a meridional ice transport forced by the differential ice shell heating between the equator and the poles. We provide analytical and numerical solutions for the layer’s characteristics, highlighting their sensitivity to critical ocean parameters. For a weakly turbulent and highly saline ocean, a strong buoyancy gradient at the base of the freshwater layer can suppress vertical tracer exchange with the deeper ocean. As a result, the freshwater layer permits relatively warm deep ocean temperatures.Key PointsCoupling of Europa’s ocean circulation and the ice shell impacts global stratificationA low‐latitude freshwater layer may suppress vertical heat and tracer transportParameter space is explored based on properties observed by future missionsPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137725/1/grl56051.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137725/2/grl56051-sup-0001-TextS1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137725/3/grl56051_am.pd

    Integration of the Total Lightning Jump Algorithm into Current Operational Warning Environment Conceptual Models

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    Key points that this analysis will begin to address are: 1)What physically is going on in the cloud when there is a jump in lightning? - Updraft variations, ice fluxes. 2)How do these processes fit in with severe storm conceptual models? 3)What would this information provide an end user (i.e., the forecaster)? - Relate LJA to radar observations, like changes in reflectivity, MESH, VIL, etc. based multi-Doppler derived physical relationships 4) How do we best transistionthis algorithm into the warning decision process. The known relationship between lightning updraft strength/volume and precipitation ice mass production can be extended to the concept of the lightning jump. Examination of the first lightning jump times from 329 storms in Schultz et al. shows an increase in the mean reflectivity profile and mixed phase echo volume during the 10 minutes prior to the lightning jump. Limited dual-Doppler results show that the largest lightning jumps are well correlated in time with increases in updraft strength/volume and precipitation ice mass production; however, the smaller magnitude lightning jumps appear to have more subtle relationships to updraft and ice mass characteristics

    Physical and Dynamical Linkages Between Lightning Jumps and Storm Conceptual Models

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    The presence and rates of total lightning are both correlated to and physically dependent upon storm updraft strength, mixed phase precipitation volume and the size of the charging zone. The updraft modulates the ingredients necessary for electrification within a thunderstorm, while the updraft also plays a critical role in the development of severe and hazardous weather. Therefore utilizing this relationship, the monitoring of lightning rates and jumps provides an additional piece of information on the evolution of a thunderstorm, more often than not, at higher temporal resolution than current operational radar systems. This correlation is the basis for the total lightning jump algorithm that has been developed in recent years. Currently, the lightning jump algorithm is being tested in two separate but important efforts. Schultz et al. (2014; this conference) is exploring the transition of the algorithm from its research based formulation to a fully objective algorithm that includes storm tracking, Geostationary Lightning Mapper (GLM) Proxy data and the lightning jump algorithm. Chronis et al. (2014) provides context for the transition to current operational forecasting using lightning mapping array based products. However, what remains is an end-to-end physical and dynamical basis for coupling total lightning flash rates to severe storm manifestation, so the forecaster has a reason beyond simple correlation to utilize the lightning jump algorithm within their severe storm conceptual models. Therefore, the physical basis for the lightning jump algorithm in relation to severe storm dynamics and microphysics is a key component that must be further explored. Many radar studies have examined flash rates and their relationship to updraft strength, updraft volume, precipitation-sized ice mass, etc.; however, their relationship specifically to lightning jumps is fragmented within the literature. Thus the goal of this study is to use multiple Doppler and polarimetric radar techniques to resolve the physical and dynamical storm characteristics specifically around the time of the lightning jump. This information will help forecasters anticipate lightning jump occurrence, or even be of use to determine future characteristics of a given storm (e.g., development of a mesocyclone, downdraft, or hail signature on radar), providing additional lead time/confidence in the severe storm warning paradigm

    Inter-Comparison of Lightning Trends from Ground-Based Networks During Severe Weather: Applications Toward GLM

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    The planned GOES-R Geostationary Lightning Mapper (GLM) will provide total lightning data on the location and intensity of thunderstorms over a hemispheric spatial domain. Ongoing GOES-R research activities are demonstrating the utility of total flash rate trends for enhancing forecasting skill of severe storms. To date, GLM total lightning proxy trends have been well served by ground-based VHF systems such as the Northern Alabama Lightning Mapping Array (NALMA). The NALMA (and other similar networks in Washington DC and Oklahoma) provide high detection efficiency (> 90%) and location accuracy (< 1 km) observations of total lightning within about 150 km from network center. To expand GLM proxy applications for high impact convective weather (e.g., severe, aviation hazards), it is desirable to investigate the utility of additional sources of continuous lightning that can serve as suitable GLM proxy over large spatial scales (order 100 s to 1000 km or more), including typically data denied regions such as the oceans. Potential sources of GLM proxy include ground-based long-range (regional or global) VLF/LF lightning networks such as the relatively new Vaisala Global Lightning Dataset (GLD360) and Weatherbug Total Lightning Network (WTLN). Before using these data in GLM research applications, it is necessary to compare them with LMAs and well-quantified cloud-to-ground (CG) lightning networks, such as Vaisala s National Lightning Detection Network (NLDN), for assessment of total and CG lightning location accuracy, detection efficiency and flash rate trends. Preliminary inter-comparisons from these lightning networks during selected severe weather events will be presented and their implications discussed

    Escherichia coli HU protein has a role in the repair of abasic sites in DNA

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    HU is one of the most abundant DNA binding proteins in Escherichia coli. We find that it binds strongly to DNA containing an abasic (AP) site or tetrahydrofuran (THF) (apparent Kd ≈50 nM). It also possesses an AP lyase activity that cleaves at a deoxyribose but not at a THF residue. The binding and cleavage of an AP site was observed only with the HUαβ heterodimer. Site-specific mutations at K3 and R61 residues led to a change in substrate binding and cleavage. Both K3A(α)K3A(β) and R61A(α)R61A(β) mutant HU showed significant reduction in binding to DNA containing AP site; however, only R61A(α)R61A(β) mutant protein exhibited significant loss in AP lyase activity. Both K3A(α)K3A(β) and R61K(α)R61K(β) showed slight reduction in AP lyase activities. The function of HU protein as an AP lyase was confirmed by the ability of hupA or hupB mutations to further reduce the viability of an E. coli dut(Ts) xth mutant, which generates lethal AP sites at 37°C; the hupA and hupB derivatives, respectively, had a 6-fold and a 150-fold lower survival at 37°C than did the parental strain. These data suggest, therefore, that HU protein plays a significant role in the repair of AP sites in E. coli

    Relationships Between Long-Range Lightning Networks and TRMM/LIS Observations

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    Recent advances in long-range lightning detection technologies have improved our understanding of thunderstorm evolution in the data sparse oceanic regions. Although the expansion and improvement of long-range lightning datasets have increased their applicability, these applications (e.g., data assimilation, atmospheric chemistry, and aviation weather hazards) require knowledge of the network detection capabilities. The present study intercompares long-range lightning data with observations from the Lightning Imaging Sensor (LIS) aboard the Tropical Rainfall Measurement Mission (TRMM) satellite. The study examines network detection efficiency and location accuracy relative to LIS observations, describes spatial variability in these performance metrics, and documents the characteristics of LIS flashes that are detected by the long-range networks. Improved knowledge of relationships between these datasets will allow researchers, algorithm developers, and operational users to better prepare for the spatial and temporal coverage of the upcoming GOES-R Geostationary Lightning Mapper (GLM)

    A randomized trial of memantine as treatment for spasticity in multiple sclerosis

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    Abstract We report the results of a single center randomized, double-blind, placebo-controlled, parallel group trial of memantine in adults with multiple sclerosis and spasticity conducted over 12 weeks. Eligible MS patients had to have an Ashworth spasticity rating of 2 or higher in at least one lower extremity muscle group. Subjects were randomized to receive either placebo or memantine 10 mg twice a day. The primary outcome measure for efficacy was the change in Ashworth Spasticity Scale Score. Although well tolerated, memantine treatment did not demonstrate efficacy in treatment of spasticity in this 12-week small exploratory study
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