Using a mixture model for multiple imputation in the presence of outliers: the ‘Healthy for life’ project

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74845/1/j.1467-9876.2007.00565.x.pd

The serotonin 1A receptor modulates the social behaviour within groups of a cooperatively-breeding cichlid.

The neurotransmitter serotonin (5-HT) reduces aggressive behaviour in a number of vertebrates, and the 5-HT1A receptor is known to be involved in this regulation. However, the role of this receptor in the modulation of sociopositive behaviour remains largely unknown. Here we investigated the role of the 5-HT1A receptor in the regulation of aggressive, submissive and affiliative behaviour in the cooperatively-breeding cichlid Neolamprologus pulcher. In two experiments, we performed intramuscular injections of a 5-HT1A agonist (8-OH-DPAT) and antagonist (Way-100635) followed by recordings of social behaviour of injected fish within their social groups. We determined the concentrations and post-injection times when the drugs had the greatest effect on social behaviour. We recorded spontaneous social behaviour in both experiments. In the second experiment we also recorded behaviour after social groups received a territorial challenge by live presentations of either conspecifics or egg predators. The 5-HT1A agonist caused an increase in aggression and a decrease in submission and affiliation, whereas the antagonist had the opposite effects. Thus, the 5-HT1A receptor plays an important regulatory role not only for aggressive but also sociopositive behaviour

Real world CO2 and NOx emissions from 149 Euro 5 and 6 diesel, gasoline and hybrid passenger cars.

In this study CO2 and NOx emissions from 149 Euro 5 and 6 diesel, gasoline and hybrid passenger cars were compared using a Portable Emissions Measurement System (PEMS). The models sampled accounted for 56% of all passenger cars sold in Europe in 2016. We found gasoline vehicles had CO2 emissions 13-66% higher than diesel. During urban driving, the average CO2 emission factor was 210.5 (sd. 47) gkm-1 for gasoline and 170.2 (sd. 34) gkm-1 for diesel. Half the gasoline vehicles tested were Gasoline Direct Injection (GDI). Euro 6 GDI engines <1.4ℓ delivered ~17% CO2 reduction compared to Port Fuel Injection (PFI). Gasoline vehicles delivered an 86-96% reduction in NOx emissions compared to diesel cars. The average urban NOx emission from Euro 6 diesel vehicles 0.44 (sd. 0.44) gkm-1 was 11 times higher than for gasoline 0.04 (sd. 0.04) gkm-1. We also analysed two gasoline-electric hybrids which out-performed both gasoline and diesel for NOx and CO2. We conclude action is required to mitigate the public health risk created by excessive NOx emissions from modern diesel vehicles. Replacing diesel with gasoline would incur a substantial CO2 penalty, however greater uptake of hybrid vehicles would likely reduce both CO2 and NOx emissions. Discrimination of vehicles on the basis of Euro standard is arbitrary and incentives should promote vehicles with the lowest real-world emissions of both NOx and CO2

Auditing Symposium V: Proceedings of the 1980 Touche Ross/University of Kansas Symposium on Auditing Problems

Historical perspective of government auditing -- With special reference to the U.S general accounting office / Leo Herbert; Discussant\u27s response to an historical perspective of government auditing with special reference to the U.S General Accounting Office / Richard E. Brown; Critical requirements of a system of internal accounting control / Robert J. Sack; Discussant\u27s response to critical requirements of a system of internal accounting control / Jay M. Smith; Taxonomization of internal controls and errors for audit research / Miklos A. Vasarhelyi; Discussant\u27s response to taxonomization of internal controls and errors for audit research / John K. Wulff; Investigation of a measurement based approach to the evaluation of audit evidence / Theodore J. Mock, Arnold Wright; Discussant\u27s response to an investigation of a measurement based approach to the evaluation of audit evidence / Bart H. Ward; Authors\u27 reply to discussant\u27s response: An investigation of a measurement based approach to the evaluation of audit evidence / Theodore J. Mock, Arnold Wright; Look at the record on auditor detection of management fraud / Donald R. Ziegler; Discussant\u27s response to a look at the record on auditor detection of management fraud / Robert L. Grinaker; Auditing implications derived from a review of cases and articles relating to fraud / W. Steve Albrecht, Marshall B. Romney; Discussant\u27s response to auditing implications derived from a review of cases and articles related to fraud / Henry J. Murphy; Unique audit problems of small businesses that operate under managerial dominance / Dan M. Guy; Discussant\u27s response to unique audit problems of small businesses that operate under managerial dominance / Albert A. Armstrong; Accounting profession in the 1980\u27s -- Some SEC perspectives / George C. Mead;https://egrove.olemiss.edu/dl_proceedings/1004/thumbnail.jp

Auditing Symposium VI: Proceedings of the 1982 Touche Ross/University of Kansas Symposium on Auditing Problems

Evolution of Audit reporting / Douglas R. Carmichael, Alan J. Winters; Discussant\u27s response to audit detection of financial statement errors / William F. Messier; Multi-Attribute model for audit evaluation / Theodore J. Mock, Michael G. Samet; Discussant\u27s response to a multi-attribute model for audit evaluation / Joseph X. Loftus; Some thoughts on materiality / Kenneth W. Stringer; Discussant\u27s response to some thought on materiality / Joseph J. Schultz; SAS 34 procedures vs forecast reviews: The Gap in GAAS / Robert Kay; Discussant\u27s response to SAS 34 procedures vs forecast reviews: The gap in GAAS / William R. Kinney; Development in governmental auditing: Their impact on the academic and business communities / Richard E. Brown; Discussant\u27s response to the evolution of audit reporting / J. Alex Milburn; How not to communicate material and immaterial weaknesses in accounting controls / Wanda A. Wallace; Discussant\u27s response to how not to communicate material and immaterial weaknesses in accounting controls / Alan N. Certain; Human information processing research in auditing A review and synthesis / Robert H. Ashton; Discussant\u27s response to human information processing research in auditing: a review and synthesis / Gary L. Holstrum; Audit detection of financial statement errors: Implications for the practitioner / Robert E. Hylashttps://egrove.olemiss.edu/dl_proceedings/1005/thumbnail.jp

Lung Particulate Burdens of Subjects from the Cincinnati, Ohio Urban Area

Because of the relatively small data base existing for lung particulate burdens of subjects with no overt pneumoconioses, the total exogenous lung particulate concentrations of 91 subjects from the Cincinnati, Ohio urban area were determined using an automated scanning electron microscope-energy dispersive x-ray analysis-image analysis system. Four of these subjects were foundry workers and had the highest exogenous particle concentrations seen in the 91 lungs, ranging from 1860 to 2990 x 106 particles per gram of dry lung (ppg). The average exogenous particle concentration for the remaining 87 subjects was 476 ± 380 x 106 ppg with a range of 71 to 1860 x 106 ppg. The median size of the exogenous particles in the 87 lungs was narrow, ranging from 0.37 to 1.02 µm. The geometric mean particle size over all 87 lungs was 0.60 µm with a geometric standard deviation (σg) of 2.35. The total exogenous particle levels were elevated for the male subjects compared to females (p=0.015), and were positively associated with age (p=0. 021). However, no correlation was seen between total particle concentration and race or smoking history

Driving Opposing Behaviors with Ensembles of Piriform Neurons

SummaryAnatomic and physiologic studies have suggested a model in which neurons of the piriform cortex receive convergent input from random collections of glomeruli. In this model, odor representations can only be afforded behavioral significance upon experience. We have devised an experimental strategy that permits us to ask whether the activation of an arbitrarily chosen subpopulation of neurons in piriform cortex can elicit different behavioral responses dependent upon learning. Activation of a small subpopulation of piriform neurons expressing channelrhodopsin at multiple loci in the piriform cortex, when paired with reward or shock, elicits either appetitive or aversive behavior. Moreover, we demonstrate that different subpopulations of piriform neurons expressing ChR2 can be discriminated and independently entrained to elicit distinct behaviors. These observations demonstrate that the piriform cortex is sufficient to elicit learned behavioral outputs in the absence of sensory input. These data imply that the piriform does not use spatial order to map odorant identity or behavioral output.PaperCli

Microwave Spectroscopy

Contains research objectives and reports on four research projects.Signal Corps Contract DA36-039-sc-7489