542 research outputs found
A Multi-Dimensional Trust Model for Heterogeneous Contract Observations
In this paper we develop a novel probabilistic model of computational trust that allows agents to exchange and combine reputation reports over heterogeneous, correlated multi-dimensional contracts. We consider the specific case of an agent attempting to procure a bundle of services that are subject to correlated quality of service failures (e.g. due to use of shared resources or infrastructure), and where the direct experience of other agents within the system consists of contracts over different combinations of these services. To this end, we present a formalism based on the Kalman filter that represents trust as a vector estimate of the probability that each service will be successfully delivered, and a covariance matrix that describes the uncertainty and correlations between these probabilities. We describe how the agentsā direct experiences of contract outcomes can be represented and combined within this formalism, and we empirically demonstrate that our formalism provides significantly better trustworthiness estimates than the alternative of using separate single-dimensional trust models for each separate service (where information regarding the correlations between each estimate is lost)
Information Agents for Pervasive Sensor Networks
In this paper, we describe an information agent, that resides on a mobile computer or personal digital assistant (PDA), that can autonomously acquire sensor readings from pervasive sensor networks (deciding when and which sensor to acquire readings from at any time). Moreover, it can perform a range of information processing tasks including modelling the accuracy of the sensor readings, predicting the value of missing sensor readings, and predicting how the monitored environmental parameters will evolve into the future. Our motivating scenario is the need to provide situational awareness support to first responders at the scene of a large scale incident, and we describe how we use an iterative formulation of a multi-output Gaussian process to build a probabilistic model of the environmental parameters being measured by local sensors, and the correlations and delays that exist between them. We validate our approach using data collected from a network of weather sensors located on the south coast of England
Towards Real-Time Information Processing of Sensor Network Data using Computationally Efficient Multi-output Gaussian Processes
In this paper, we describe a novel, computationally efficient algorithm that facilitates the autonomous acquisition of readings from sensor networks (deciding when and which sensor to acquire readings from at any time), and which can, with minimal domain knowledge, perform a range of information processing tasks including modelling the accuracy of the sensor readings, predicting the value of missing sensor readings, and predicting how the monitored environmental variables will evolve into the future. Our motivating scenario is the need to provide situational awareness support to first responders at the scene of a large scale incident, and to this end, we describe a novel iterative formulation of a multi-output Gaussian process that can build and exploit a probabilistic model of the environmental variables being measured (including the correlations and delays that exist between them). We validate our approach using data collected from a network of weather sensors located on the south coast of England
Murine Flt3L-derived dendritic cell mediated early immune responses are critical to controlling cell-free HTLV-1 infection
Turbulence driven by outflow-blown cavities in the molecular cloud of NGC 1333
Outflows from young stellar objects have been identified as a possible source
of turbulence in molecular clouds. To investigate the relationship between
outflows, cloud dynamics and turbulence, we compare the kinematics of the
molecular gas associated with NGC 1333, traced in 13CO(1-0), with the
distribution of young stellar objects (YSOs) within. We find a velocity
dispersion of ~ 1-1.6 km/s in 13CO that does not significantly vary across the
cloud, and is uncorrelated with the number of nearby young stellar outflows
identified from optical and submillimeter observations. However, from velocity
channel maps we identify about 20 cavities or depressions in the 13CO intensity
of scales > 0.1-0.2 pc and velocity widths 1-3 km/s. The cavities exhibit limb
brightened rims in both individual velocity channel maps and position velocity
diagrams, suggesting that they are slowly expanding. We interpret these
cavities to be remnants of past YSO outflow activity: If these cavities are
presently empty, they would fill in on time scales of a million years. This can
exceed the lifetime of a YSO outflow phase, or the transit time of the central
star through the cavity, explaining the the absence of any clear correlation
between the cavities and YSO outflows. We find that the momentum and energy
deposition associated with the expansion of the cavities is sufficient to power
the turbulence in the cloud. In this way we conclude that the cavities are an
important intermediary step between the conversion of YSO outflow energy and
momentum into cloud turbulent motions.Comment: Accepted for publication in ApJ. Check out
http://astro.pas.rochester.edu/~aquillen/coolpics.html for channel map and
PosVel movies of N133
Physical characterisation of 3C-SiC(001)/SiO2 interface using XPS
Normally-on MOSFETs were fabricated on 3C-SiC epilayers using high temperature (1300 Ā°C) wet oxidation process. XPS analysis found little carbon at the MOS interface yet the channel mobility (60 cm2/V.s) is considerably low. Si suboxides (SiOx, x<2) exist at the wet oxidised 3C-SiC/SiO2 interface, which may act as interface traps and degrade the conduction performance
Assessing the applicability of terrestrial laser scanning for mapping englacial conduits
his is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.The morphology of englacial drainage networks and their temporal evolution are poorly characterised, particularly within cold ice masses. At present, direct observations of englacial channels are restricted in both spatial and temporal resolution. Through novel use of a terrestrial laser scanning (TLS) system, the interior geometry of an englacial channel in Austre BrĆøggerbreen, Svalbard, was reconstructed and mapped. Twenty-eight laser scan surveys were conducted in March 2016, capturing the glacier surface around a moulin entrance and the uppermost 122 m reach of the adjoining conduit. The resulting point clouds provide detailed 3-D visualisation of the channel with point accuracy of 6.54 mm, despite low (<60%) overall laser returns as a result of the physical and optical properties of the clean ice, snow, hoar frost and sediment surfaces forming the conduit interior. These point clouds are used to map the conduit morphology, enabling extraction of millimetre-to-centimetre scale geometric measurements. The conduit meanders at a depth of 48 m, with a sinuosity of 2.7, exhibiting teardrop shaped cross-section morphology. This improvement upon traditional surveying techniques demonstrates the potential of TLS as an investigative tool to elucidate the nature of glacier hydrological networks, through reconstruction of channel geometry and wall composition.Peer reviewedFinal Published versio
Functional oxide as an extreme high-k dielectric towards 4H-SiC MOSFET incorporation
MOS Capacitors are demonstrated on 4H-SiC using an octahedral ABO3 ferroic thin-film as a dielectric prepared on several buffer layers. Five samples were prepared: ABO3 on SiC, ABO3 on SiC with a SiO2 buffer (10 nm and 40 nm) and ABO3 on SiC with an Al2O3 buffer (10nm and 40 nm). Depending on the buffer material the oxide forms in either the pyrochlore or perovskite phase. A better lattice match with the Al2O3 buffer yields a perovskite phase with internal switchable dipoles. Hysteresis polarization-voltage loops show an oxide capacitance of ~ 0.2 Ī¼F/cm2 in the accumulation region indicating a dielectric constant of ~120
Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach
Structure-guided expansion of a fragment hit for the ATAD2 bromodomain enabled improvement in ATAD2 inhibition and selectivity over BRD4.</p
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Effect of monthly vitamin D3 supplementation in healthy adults on adverse effects of earthquakes: randomised controlled trial
Objective: To determine whether supplementation with vitamin D improves resilience to the adverse effects of earthquakes. Design: Opportunistic addition to an established randomised double blind placebo controlled trial. Setting: Christchurch, New Zealand, where a prolonged series of catastrophic earthquakes beginning on 4 September 2010 occurred, which caused widespread destruction, fatalities, and extensive psychological damage. Participants: 322 healthy adults (241 women; 81 men) aged 18-67 who were already participating in the vitamin D and acute respiratory infections study (VIDARIS) between February 2010 and November 2011. Intervention Participants were randomised to receive an oral dose of either 200 000 IU vitamin D3 monthly for two months then 100 000 IU monthly (n=161) or placebo (n=161) for a total of 18 months. Main outcome measure This is a post hoc analysis from the previously published VIDARIS trial. The primary endpoint in the current analysis was the self reported effects and overall adverse impact of the Christchurch earthquakes as assessed by questionnaire four months after the most destructive earthquake on 22 February 2011, which was used as the index event. The secondary end point was the number of āpsychologicalā adverse events that participants reported at their usual monthly appointments as part of the original VIDARIS trial. Results: 308 participants completed the earthquake impact questionnaire (n=152 in the vitamin D group and 156 in the placebo group). There was no significant difference in the number of self reported adverse effects between those receiving vitamin D supplementation and those receiving placebo. There was also no difference in the overall adverse impact score between treatment groups (Ļ2 P=0.44). The exception was that those in the vitamin D group experienced more adverse effects on family relationships (22% v 13%; Ļ2 P=0.03). The number of psychological adverse eventsāsuch as fatigue, stress, anxiety, and insomniaāthat participants reported at their usual monthly appointments was significantly higher after the earthquake (Ļ2 P=0.007) but did not differ between treatment groups. Conclusion: In this trial, vitamin D supplementation did not reduce the adverse impact of earthquakes in healthy adults. Trial registration Australian New Zealand Clinical Trials Registry (anzctr.org.au) ACTRN1260900048622
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