1,851 research outputs found

    Preface: Social and Technical Issues in Testing: Implications for Test Construction and Usage

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    Tests are constructed and used to facilitate assessment and understanding of human beings in all their multifaceted complexity. Hence, testing by its very nature is both a scientific and a social endeavor. The interplay between testing and society has resulted in both praise and criticism from concerned citizens, psychologists, educators, and numerous other professional and consumer groups. For over 40 years, Oscar K. Buros, as Director of The Institute of Mental Measurements and Editor of the Mental Measurements Yearbooks. contributed immensely to this interplay between testing practices and societal issues. On March 19, 1978, Oscar Buros died. Luella Buros , his wife and lifelong helpmate, completed the work on The Eighth Mental Measurements Yearbook with the support of the Institute\u27s devoted staff. She also took steps to relocate the Institute to ensure the continuation of the Institute\u27s scholarly work and services for test consumers. The new Buros Institute of Mental Measurements is now at the University of Nebraska- Lincoln and is under grant from The University of Nebraska Foundation. An important objective of the new Buros Institute is to conduct an extended outreach effort that will help communicate more effectively with test users about contemporary issues in testing . Thus, it was the combination of recent social issues focusing on testing and our desire to fulfill more vigorously the mission of the Buros Institute that motivated the development of an annual scholarly symposium and this series on measurement and testing. We intend each symposium and volume in this series to present state-of-the art knowledge that will contribute to the improvement of test construction and test usage. Such a schema will incorporate topics across a broad spectrum such as theoretical models of human behavior, test standardization procedures, social and legal factors in testing, administration of testing programs , and test-based decision making. Thus, the series will be focused thematically and yet be flexible enough to integrate current and future measurement and testing issues into its schema. The success of our first Buros- Nebraska symposium and this volume is the result of the efforts of many individuals. We thank Luella Buros for having faith in us to carryon and extend a tradition that has become so important to the measurement field and to test users. Barbara Plake , as editor of the first volume in the series, made conceptual and editorial contributions that were of critical importance to its success. Finally, we want to thank Larry Erlbaum for his support, encouragement, and commitment to the project and to its timely completion

    Trace Gas Emissions from Biomass Burning inferred from Aerosol Optical Depth

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    We have observed strong correlations between simultaneous and co-located measurements of aerosol optical depth and column amounts of carbon monoxide, hydrogen cyanide, formaldehyde and ammonia in bushfire smoke plumes over SE Australia during the Austral summers of 2001/2002 and 2002/2003. We show how satellite-derived aerosol optical depth maps may be used in conjunction with these correlations to determine the total amounts of these gases present in a fire-affected region. This provides the basis of a method for estimating total emissions of trace gases from biomass burning episodes using visible radiances measured by satellite

    Strain-specificity in the hydrogen sulphide signalling network following dietary restriction in recombinant inbred mice

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    Modulation of the ageing process by dietary restriction (DR) across multiple taxa is well established. While the exact mechanism through which DR acts remains elusive, the gasotransmitter hydrogen sulphide (H2S) may play an important role. We employed a comparative-type approach using females from three ILSXISS recombinant inbred mouse strains previously reported to show differential lifespan responses following 40% DR. Following long-term (10 months) 40% DR, strain TejJ89—reported to show lifespan extension under DR—exhibited elevated hepatic H2S production relative to its strain-specific ad libitum (AL) control. Strain TejJ48 (no reported lifespan effect following 40% DR) exhibited significantly reduced hepatic H2S production, while H2S production was unaffected by DR in strain TejJ114 (shortened lifespan reported following 40% DR). These differences in H2S production were reflected in highly divergent gene and protein expression profiles of the major H2S production and disposal enzymes across strains. Increased hepatic H2S production in TejJ89 mice was associated with elevation of the mitochondrial H2S-producing enzyme 3-mercaptopyruvate sulfurtransferase (MPST). Our findings further support the potential role of H2S in DR-induced longevity and indicate the presence of genotypic-specificity in the production and disposal of hepatic H2S in response to 40% DR in mice

    Real-time wavefront control for the PALM-3000 high order adaptive optics system

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    We present a cost-effective scalable real-time wavefront control architecture based on off-the-shelf graphics processing units hosted in an ultra-low latency, high-bandwidth interconnect PC cluster environment composed of modules written in the component-oriented language of nesC. We demonstrate the architecture is capable of supporting the most computation and memory intensive wavefront reconstruction method (vector-matrix-multiply) at frame rates up to 2 KHz with latency under 250 &mgr;s for the PALM-3000 adaptive optics systems, a state-of-the-art upgrade on the 5.1 meter Hale Telescope that consists of a 64x64 subaperture Shack-Hartmann wavefront sensor and a 3368 active actuator high order deformable mirror in series with a 349 actuator "woofer" DM. This architecture can easily scale up to support larger AO systems at higher rates and lower latency

    Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging.

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    Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN6. It is a recessive genetic lysosomal storage disease characterised by progressive neurodegeneration. It starts insidiously and leads to blindness, epilepsy and dementia in affected children. Sheep that are homozygous for a natural mutation in CLN6 have an ovine form of Batten disease Here, we used in vivo magnetic resonance imaging to track brain changes in 4 unaffected carriers and 6 affected Batten disease sheep. We scanned each sheep 4 times, between 17 and 22 months of age. Cortical atrophy in all sheep was pronounced at the baseline scan in all affected Batten disease sheep. Significant atrophy was also present in other brain regions (caudate, putamen and amygdala). Atrophy continued measurably in all of these regions during the study. Longitudinal MRI in sheep was sensitive enough to measure significant volume changes over the relatively short study period, even in the cortex, where nearly 40% of volume was already lost at the start of the study. Thus longitudinal MRI could be used to study the dynamics of progression of neurodegenerative changes in sheep models of Batten disease, as well as to assess therapeutic efficacy
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