918 research outputs found
Loyalty and longevity in audience listening: investigating experiences of attendance at a chamber music festival
There is currently much concern amongst arts organisations and their marketing departments that audiences for classical music are in decline, yet little research has so far investigated the experiences of long-term listeners for insight on audience development and retention. This paper presents a case study of the Music in the Round chamber music festival, conducted over a three year period which included the retirement of the host string quartet, the appointment of a new resident ensemble, and associated changes in audience attitudes and priorities. The interaction between individual listening and collective membership of an audience is discussed, and the potential considered for understanding classical concert-goers as ‘fans’ or ‘consumers’
An Investigation of the Effects of Gender, Socioeconomic Status, and Age on Mathematics Outcomes of In-Person and Online Learning
The coronavirus pandemic created a unique situation where a rural school district in western Ohio gave students a choice to attend school in-person with face-to-face teachers or take courses online through an asynchronous online platform. The state mathematics grade level and end-of-course test scores were taken by both groups of students in the spring of 2021. An analysis of the state grade level test scores for grades 3-8 revealed significant predictors of instructional mode, socioeconomic status, and gender. Taking courses online predicted a lower score by 23 points, the socioeconomically disadvantaged scored 20 points lower, and females were behind by more than 9 points. An analysis of the state end-of-course test scores revealed one significant predictor, that of instructional mode, with online students behind by nearly 14 points. Further analyses revealed the mean test scores of online students were significantly lower than that of in-person students in each age group and test type. There were no significant interactions revealed between any of the analyzed predictors. Online students were consistently lower in each test type and age group; this gap was not significantly different among any of the subgroups of socioeconomic status, gender, or age compared to the whole population
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Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking.
Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular interaction between numerous cell types including macrophages. Previous studies of hematopoietic stem and progenitor cell (HSPC) transplantation for the lysosomal storage disorder cystinosis have shown that HSPC-derived macrophages form TNTs to deliver cystinosin-bearing lysosomes to cystinotic cells, leading to tissue preservation. Here, we explored if macrophage polarization to either proinflammatory M1-like M(LPS/IFNγ) or anti-inflammatory M2-like M(IL-4/IL-10) affected TNT-like protrusion formation, intercellular transport and, ultimately, the efficacy of cystinosis prevention. We designed new automated image processing algorithms used to demonstrate that LPS/IFNγ polarization decreased bone marrow-derived macrophages (BMDMs) formation of protrusions, some of which displayed characteristics of TNTs, including cytoskeletal structure, 3D morphology and size. In contrast, co-culture of macrophages with cystinotic fibroblasts yielded more frequent and larger protrusions, as well as increased lysosomal and mitochondrial intercellular trafficking to the diseased fibroblasts. Unexpectedly, we observed normal protrusion formation and therapeutic efficacy following disruption of anti-inflammatory IL-4/IL-10 polarization in vivo by transplantation of HSPCs isolated from the Rac2-/- mouse model. Altogether, we developed unbiased image quantification systems that probe mechanistic aspects of TNT formation and function in vitro, while HSPC transplantation into cystinotic mice provides a complex in vivo disease model. While the differences between polarization cell culture and mouse models exemplify the oversimplicity of in vitro cytokine treatment, they simultaneously demonstrate the utility of our co-culture model which recapitulates the in vivo phenomenon of diseased cystinotic cells stimulating thicker TNT formation and intercellular trafficking from macrophages. Ultimately, we can use both approaches to expand the utility of TNT-like protrusions as a delivery system for regenerative medicine
GP perspectives on hospital discharge letters : an interview and focus group study
Background: Written discharge communication following inpatient or outpatient clinic discharge is essential for communicating information to the GP, but GPs’ opinions on discharge communication are seldom sought. Patients are sometimes copied into this communication, but the reasons for this variation, and the resultant effects, remain unclear.
Aim: To explore GP perspectives on how discharge letters can be improved in order to enhance patient outcomes.
Design & setting: The study used narrative interviews with 26 GPs from 13 GP practices within the West Midlands, England.
Method: Interviews were transcribed and data were analysed using corpus linguistics (CL) techniques.
Results Elements pivotal to a successful letter were: diagnosis, appropriate follow-up plan, medication changes and reasons, clinical summary, investigations and/or procedures and outcomes, and what information has been given to the patient. GPs supported patients receiving discharge letters and expounded a number of benefits of this practice; for example, increased patient autonomy. Nevertheless, GPs felt that if patients are to receive direct discharge letter copies, modifications such as use of lay language and avoidance of acronyms may be required to increase patient understanding.
Conclusion: GPs reported that discharge letters frequently lacked content items they assessed to be important; GPs highlighted that this can have subsequent ramifications on resources and patient experiences. Templates should be devised that put discharge letter elements assessed to be important by GPs to the forefront. Future research needs to consider other perspectives on letter content, particularly those of patients
A Pilot Study: Magic Tricks in the ELL Classroom Increasing Verbal Communication Initiative and Self-Efficacy
Instructional practices for English language Learners (ELLs) are multifaceted. They must address everything from communication skills to learner motivation. As a means of tapping student curiosity, learning to perform simple magic tricks is a creative task-based language teaching approach that promotes student self-confidence and engages them in interactionally authentic language. The learning of a magic trick becomes the means of helping students to use the linguistic knowledge they already have as well as a source for new linguistic knowledge. Teaching ELLs simple magic tricks is one approach that increases student communication and produces improvement in academics, self-confidence, resiliency, and social skills
Using the Theory of Emotional Stakeholders to Experimentally Test the Influence of Proxy Communicators about Organizational Crises in Digital News Reports
The emergence of new and social media has transformed the way that stakeholders and organizations interact between and amongst each other. Online news consumers are now able to directly respond to crisis news reports by offering their own interpretation, thus expanding the diversity of viewpoints audiences are exposed to (Carpenter, 2010; Springer, 2014). Using the Theory of Emotional Stakeholders framework our study aims (1) to understand how positive and negative user-generated comments in response to online news reports of crisis events impacts audience perceptions of organizational blame; (2) to examine the persuasive effects of user comments when expert or official organizational responses are provided; and, (3) to measure the affective response to online news reports including user comments. Using experimental procedures our findings show that user comments from organizations, faith-holders, and hate-holders contribute to audience evaluations of crisis responsibility, both causal and treatment. Results found that user comments from faith-holders reduced causal responsibility in the intentional cluster compared to the control condition; however, when organizations were facing preventable crises, user comments from faith-holders amplified perceived treatment responsibility. A detailed description of the findings, discussion, limitations and future directions are provided
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