Dual-mode of insulin action controls GLUT4 vesicle exocytosis

Insulin releases an intracellular brake and promotes fusion pore expansion to translocate GLUT4 vesicles, and switches vesicle trafficking between distinct exocytic circuits

The Use of Cash and the Size of the Shadow Economy in Sweden

We use an 'unexplained demand for cash' approach to measure the size of the shadow economy in Sweden. The size of the shadow economy is found to have increased from 3.8 to 6.5 per cent of GDP from 1990 to 2004. This result is also supported by our finding of an increased residual between households' recorded disposable income and their consumption, investments and changes in net financial positions. Moreover, the correlation between the demand for cash that cannot be explained by recorded transactions and this residual is strong

A 150-Year Perspective on Swedish Capital Income Taxation

This paper describes the evolution of capital income taxation, including corporate, dividend, interest, capital gains and wealth taxation, in Sweden between 1862 and 2010. To illustrate the evolution, we present annual time-series data on the marginal effective tax rates on capital income (METR) for a marginal investment financed with new share issues, retained earnings or debt. Tax tables covering the period are presented. These data are unique in their consistency, thoroughness and time span covered. The METR is low, is stable and does not exceed five percent until World War I, when it starts to drift somewhat upward and vary depending on the source of finance. The outbreak of World War II starts a period when the magnitude and variation of the METR sharply increases. The METR peaks during the 1970s and 1980s and often exceeds 100 percent. The 1990-1991 tax reform and lower inflation reduce the magnitude and variation of the METR. The METR varies between 15 and 40 percent at the end of the examined period

A Reform Strategy for the UK

In this chapter we outline a reform strategy to promote an entrepreneurial society in the UK. To put it in the words of the Varieties of Capitalism framework, the UK today represents a distinct liberal market economy with a deregulated environment, flexible labor markets, well-funded elite universities, and strong protection of intellectual property rights. Overall, the entrepreneurial ecosystem is supportive, but bottlenecks remain regarding radical innovation, export orientation, and informal investment. To address these shortcomings, the UK should aim at strengthening the workforce’s knowledge base and talent pool as well as the capital base from which UK entrepreneurs can draw. It furthermore is advisable to open opportunities for not only starting but also growing innovative firms in all regions in the UK

Boyan Jovanovic: recipient of the 2019 Global Award for Entrepreneurship Research

The 2019 Global Award for Entrepreneurship Research has been awarded to Professor Boyan Jovanovic at New York University in the USA. Boyan Jovanovic has developed pioneering research that advances our understanding of the competitive dynamics between incumbent firms and new entrants, entrepreneurial learning and selection processes, and the importance of entrepreneurship for the economy. Key perspectives in his research are that the entrepreneur makes employment choices based on the comparative advantage of his or her skills and that entrepreneurial firms are vehicles of technological change and knowledge diffusion that influence industry dynamics and, in turn, economic growth

A Historical Perspective on the Evolution of Finance, Knowledge, and Labor Market Institutions in Europe

Both policymakers and academics offer various strategies concerning institutions on how to stimulate entrepreneurial activity in Europe. However, historical evidence shows that the cross-national differences in these institutions are the result of long-term historical processes. A successful entrepreneurial strategy would therefore benefit from looking at the past to build and improve current institutions in the future. To provide such a historical insight, this chapter aims to answer the question: How and to what extent have the institutional factors relevant to entrepreneurial activity evolved over time? It discusses the changes in the financial, knowledge, and labor institutions over the twentieth century across European countries to be able to distinguish between institutions that are dynamic and those that are slowly changing. Using the Varieties of Capitalism (VoC) framework, it provides insight into the different patterns of institutional change and the implications of this change for the different forms of entrepreneurial activity across European countries. The historical approach presented in this chapter thus contributes to the development o

A Reform Strategy for the UK

In this chapter we outline a reform strategy to promote an entrepreneurial society in the UK. To put it in the words of the Varieties of Capitalism framework, the UK today represents a distinct liberal market economy with a deregulated environment, flexible labor markets, well-funded elite universities, and strong protection of intellectual property rights. Overall, the entrepreneurial ecosystem is supportive, but bottlenecks remain regarding radical innovation, export orientation, and informal investment. To address these shortcomings, the UK should aim at strengthening the workforce’s knowledge base and talent pool as well as the capital base from which UK entrepreneurs can draw. It furthermore is advisable to open opportunities for not only starting but also growing innovative firms in all regions in the UK