1,379 research outputs found
Stickstoffmineralisierung aus vegetabilen DĂŒngern in Kombination mit Mischkompost im Ăkologischen Landbau
Beim Einsatz von Lupinenschrot zur KopfdĂŒngung in Tomaten konnte ein positiver Primingeffekt fĂŒr Stickstoff ermittelt werden. Im Rahmen dieser Arbeit sollten die Ursachen und ZusammenhĂ€nge fĂŒr diese zusĂ€tzliche Stickstoffmobilisierung aus dem Boden geprĂŒft werden. Es wurden die DĂŒngevarianten Lupinenschrot und Erbsenschrot sowohl mit/ohne Kompost als GrunddĂŒngung im Brutversuch auf Stickstoffmineralisierungsrate und -potential geprĂŒft
Possible signatures of mixed-parity superconductivity in doped polar SrTiO3 films
Superconductors that possess both broken spatial inversion symmetry and
spin-orbit interactions exhibit a mix of spin singlet and triplet pairing.
Here, we report on measurements of the superconducting properties of
electron-doped, strained SrTiO3 films. These films have an enhanced
superconducting transition temperature and were previously shown to undergo a
transition to a polar phase prior to becoming superconducting. We show that
some films show signatures of an unusual superconducting state, such as an
in-plane critical field that is higher than both the paramagnetic and orbital
pair breaking limits. Moreover, nonreciprocal transport, which reflects the
ratio of odd versus even pairing interactions, is observed. Together, these
characteristics indicate that these films provide a tunable platform for
investigations of unconventional superconductivity
A Hierarchical Approach to Protein Molecular Evolution
Biological diversity has evolved despite the essentially infinite complexity
of protein sequence space. We present a hierarchical approach to the efficient
searching of this space and quantify the evolutionary potential of our approach
with Monte Carlo simulations. These simulations demonstrate that non-homologous
juxtaposition of encoded structure is the rate-limiting step in the production
of new tertiary protein folds. Non-homologous ``swapping'' of low energy
secondary structures increased the binding constant of a simulated protein by
relative to base substitution alone. Applications of our approach
include the generation of new protein folds and modeling the molecular
evolution of disease.Comment: 15 pages. 2 figures. LaTeX styl
Alcohols increase calmodulin affinity for Ca2+ and decrease target affinity for calmodulin
AbstractIt has been proposed that alcohols and anesthetics selectively inhibit proteins containing easily disrupted motifs, e.g., α-helices. In this study, the calcineurin/calmodulin/Ca2+ enzyme system was used to examine the effects of alcohols on calmodulin, a protein with a predominantly α-helical structure. Calcineurin phosphatase activity and Ca2+ binding were monitored as indicators of calmodulin function. Alcohols inhibited enzyme activity in a concentration-dependent manner, with two-, four- and five-carbon n-alcohols exhibiting similar leftward shifts in the inhibition curves for calmodulin-dependent and -independent activities; the former was slightly more sensitive than the latter. Ca2+ binding was measured by flow dialysis as a direct measure of calmodulin function, whereas, with the addition of a binding domain peptide, measured calmodulinâtarget interactions. Ethanol increased the affinity of calmodulin for Ca2+ in the presence and absence of the peptide, indicating that ethanol stabilizes the Ca2+ bound form of calmodulin. An increase in Ca2+ affinity was detected in a calmodulin binding assay, but the affinity of calmodulin for calcineurin decreased at saturating Ca2+. These data demonstrate that although specific regions within proteins may be more sensitive to alcohols and anesthetics, the presence of α-helices is unlikely to be a reliable indicator of alcohol or anesthetic potency
Decreased Vision and Junctional Scotoma from Pituicytoma
Pituicytomas are rare neoplasms of the sellar region. We report a case of vision loss and a junctional scotoma in a 43-year-old woman caused by compression of the optic chiasm by a pituitary tumor. The morphological and immunohistochemical characteristics of the tumor were consistent with the diagnosis of pituicytoma. The tumor was debulked surgically, and the patient's vision improved
Effects of radiative heat transfer on the structure of turbulent supersonic channel flow
International audienceThe interaction between turbulence in a minimal supersonic channel and radiative heat transfer is studied using large-eddy simulation. The working fluid is pure water vapour with temperature-dependent specific heats and molecular transport coefficients. Its line spectra properties are represented with a statistical narrow-band correlated-k model. A grey gas model is also tested. The parallel no-slip channel walls are treated as black surfaces concerning thermal radiation and are kept at a constant temperature of 1000 K. Simulations have been performed for different optical thicknesses (based on the Planck mean absorption coefficient) and different Mach numbers. Results for the mean flow variables, Reynolds stresses and certain terms of their transport equations indicate that thermal radiation effects counteract compressibility (Mach number) effects. An analysis of the total energy balance reveals the importance of radiative heat transfer, compared to the turbulent and mean molecular heat transport
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