1 research outputs found
Polymeric 3D Printed Functional Microcantilevers for Biosensing Applications
In
this study, we show for the first time the production of mass-sensitive
polymeric biosensors by 3D printing technology with intrinsic functionalities.
We also demonstrate the feasibility of mass-sensitive biosensors in
the form of microcantilever in a one-step printing process, using
acrylic acid as functional comonomer for introducing a controlled
amount of functional groups that can covalently immobilize the biomolecules
onto the polymer. The effectiveness of the application of 3D printed
microcantilevers as biosensors is then demonstrated with their implementation
in a standard immunoassay protocol. This study shows how 3D microfabrication
techniques, material characterization, and biosensor development could
be combined to obtain an engineered polymeric microcantilever with
intrinsic functionalities. The possibility of tuning the composition
of the starting photocurable resin with the addition of functional
agents, and consequently controlling the functionalities of the 3D
printed devices, paves the way to a new class of mass-sensing microelectromechanical
system devices with intrinsic properties