Atheisms and the purification of faith

Philosophers of religion have distinguished between ‘negative’ and ‘positive’ atheism. This article considers further conceptions of atheism, especially the idea that atheism can facilitate a faith in God purified of idolatrous assumptions. After introducing Bultmann’s contention that a ‘conscious atheist’ can find something transcendent in the world, this contention is interpreted through reflection on Ricoeur’s claim that the atheisms of Nietzsche and Freud serve to mediate a transition to a purified faith – a faith involving heightened receptivity to agapeic love. The troubling question of what differentiates atheism from belief in God is then discussed in the light of Simone Weil’s meditations on God’s secret presence

Vitamin D Supplementation and Prevention of Type 2 Diabetes

BACKGROUND Observational studies support an association between a low blood 25-hydroxyvitamin D level and the risk of type 2 diabetes. However, whether vitamin D supplementation lowers the risk of diabetes is unknown. METHODS We randomly assigned adults who met at least two of three glycemic criteria for prediabetes (fasting plasma glucose level, 100 to 125 mg per deciliter; plasma glucose level 2 hours after a 75-g oral glucose load, 140 to 199 mg per deciliter; and glycated hemoglobin level, 5.7 to 6.4%) and no diagnostic criteria for diabetes to receive 4000 IU per day of vitamin D3 or placebo, regardless of the baseline serum 25-hydroxyvitamin D level. The primary outcome in this time-to-event analysis was new-onset diabetes, and the trial design was event-driven, with a target number of diabetes events of 508. RESULTS A total of 2423 participants underwent randomization (1211 to the vitamin D group and 1212 to the placebo group). By month 24, the mean serum 25-hydroxyvitamin D level in the vitamin D group was 54.3 ng per milliliter (from 27.7 ng per milliliter at baseline), as compared with 28.8 ng per milliliter in the placebo group (from 28.2 ng per milliliter at baseline). After a median follow-up of 2.5 years, the primary outcome of diabetes occurred in 293 participants in the vitamin D group and 323 in the placebo group (9.39 and 10.66 events per 100 person-years, respectively). The hazard ratio for vitamin D as compared with placebo was 0.88 (95% confidence interval, 0.75 to 1.04; P = 0.12). The incidence of adverse events did not differ significantly between the two groups. CONCLUSIONS Among persons at high risk for type 2 diabetes not selected for vitamin D insufficiency, vitamin D3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases and others; D2d ClinicalTrials.gov number, NCT01942694.

Vitamin D Supplementation and Prevention of Type 2 Diabetes

BACKGROUND Observational studies support an association between a low blood 25-hydroxyvitamin D level and the risk of type 2 diabetes. However, whether vitamin D supplementation lowers the risk of diabetes is unknown. METHODS We randomly assigned adults who met at least two of three glycemic criteria for prediabetes (fasting plasma glucose level, 100 to 125 mg per deciliter; plasma glucose level 2 hours after a 75-g oral glucose load, 140 to 199 mg per deciliter; and glycated hemoglobin level, 5.7 to 6.4%) and no diagnostic criteria for diabetes to receive 4000 IU per day of vitamin D3 or placebo, regardless of the baseline serum 25-hydroxyvitamin D level. The primary outcome in this time-to-event analysis was new-onset diabetes, and the trial design was event-driven, with a target number of diabetes events of 508. RESULTS A total of 2423 participants underwent randomization (1211 to the vitamin D group and 1212 to the placebo group). By month 24, the mean serum 25-hydroxyvitamin D level in the vitamin D group was 54.3 ng per milliliter (from 27.7 ng per milliliter at baseline), as compared with 28.8 ng per milliliter in the placebo group (from 28.2 ng per milliliter at baseline). After a median follow-up of 2.5 years, the primary outcome of diabetes occurred in 293 participants in the vitamin D group and 323 in the placebo group (9.39 and 10.66 events per 100 person-years, respectively). The hazard ratio for vitamin D as compared with placebo was 0.88 (95% confidence interval, 0.75 to 1.04; P = 0.12). The incidence of adverse events did not differ significantly between the two groups. CONCLUSIONS Among persons at high risk for type 2 diabetes not selected for vitamin D insufficiency, vitamin D3 supplementation at a dose of 4000 IU per day did not result in a significantly lower risk of diabetes than placebo. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases and others; D2d ClinicalTrials.gov number, NCT01942694.

Seasonal and Annual Changes of the Regional Tropical Belt in GPS-RO Measurements and Reanalysis Datasets

The width of the tropical belt has been analyzed with a variety of metrics, often based on zonal-mean data from reanalyses. However, constraining the global and regional tropical width requires both a global spatial-resolving observational dataset and an appropriate metric to take advantage of such data. The tropical tropopause break is arguably such a metric. This study aims to evaluate the performance of different reanalyses and metrics with a focus on depicting regional tropical belt width. We choose four distinct tropopause-break metrics derived from global positioning system radio occultation (GPS-RO) satellite data and four modern reanalyses (ERA-Interim, MERRA-2, JRA-55, and CFSR). We show that reanalyses generally reproduce the regional tropical tropopause break to within 10° of that in GPS-RO data—but that the tropical width is somewhat sensitive (within 4°) to how data are averaged zonally, moderately sensitive (within 10°) to the dataset resolution, and more sensitive (20° over the Northern Hemisphere Atlantic Ocean during June–August) to the choice of metric. Reanalyses capture the poleward displacement of the tropical tropopause break over land and equatorward displacement over ocean during summertime, and the reverse during the wintertime. Reanalysis-based tropopause breaks are also generally well correlated with those from GPS-RO, although CFSR reproduces 14-yr trends much more closely than others (including ERA-Interim). However, it is hard to say which dataset is the best match of GPS-RO. We further find that the tropical tropopause break is representative of the subtropical jet latitude and the Northern Hemisphere edge of the Hadley circulation in terms of year-to-year variations

Regional Widening of Tropical Overturning: Forced Change, Natural Variability, and Recent Trends

The width of the tropical Hadley circulation (HC) has garnered intense interest in recent decades, owing to the emerging evidence for its expansion in observations and models and to the anticipated impacts on surface climate in its descending branches. To better clarify the causes and impacts of tropical widening, this work generalizes the zonal mean HC to the regional level by defining meridional overturning cells (RC) using the horizontally divergent wind. The edges of the RC are more closely connected to surface hydroclimate than more traditional metrics of regional tropical width (such as the sea level pressure ridge) or even than the zonal mean HC. Simulations reveal a robust weakening of the RC in response to greenhouse gas increases, along with a widening of the RC in some regions. For example, simulated widening of the zonal mean HC in the Southern Hemisphere appears to arise in large part from regional overturning anomalies over the Eastern Pacific, where there is no clear RC. Unforced interannual variability in the position of the zonal mean HC edge is associated with a more general regional widening. These distinct regional signatures suggest that the RCs may be well suited for the attribution of observed circulation trends. The spatial pattern of regional meridional overturning trends in reanalyses corresponds more closely to the pattern associated with unforced interannual variability than to the pattern associated with CO2 forcing, suggesting a large contribution of natural variability to the recent observed tropical widening trends

Tropical widening: From global variations to regional impacts

Over the past 15 years, numerous studies have suggested that the sinking branches of Earth’s Hadley circulation and the associated subtropical dry zones have shifted poleward over the late twentieth century and early twenty-first century. Early estimates of this tropical widening from satellite observations and reanalyses varied from 0.25° to 3° latitude per decade, while estimates from global climate models show widening at the lower end of the observed range. In 2016, two working groups, the U.S. Climate Variability and Predictability (CLIVAR) working group on the Changing Width of the Tropical Belt and the International Space Science Institute (ISSI) Tropical Width Diagnostics Intercomparison Project, were formed to synthesize current understanding of the magnitude, causes, and impacts of the recent tropical widening evident in observations. These working groups concluded that the large rates of observed tropical widening noted by earlier studies resulted from their use of metrics that poorly capture changes in the Hadley circulation, or from the use of reanalyses that contained spurious trends. Accounting for these issues reduces the range of observed expansion rates to 0.25°–0.5° latitude decade$^{‒1}$—within the range from model simulations. Models indicate that most of the recent Northern Hemisphere tropical widening is consistent with natural variability, whereas increasing greenhouse gases and decreasing stratospheric ozone likely played an important role in Southern Hemisphere widening. Whatever the cause or rate of expansion, understanding the regional impacts of tropical widening requires additional work, as different forcings can produce different regional patterns of widening