The Stanley Kunitz-Stockmal Collection

Stanley Kunitz was born in Worcester in 1905 and shortly after college moved away. Beginning in the 1960s, he returned to give poetry readings and to receive honors. Kunitz searched unsuccessfully for his boyhood home on Woodford Street. Then, in 1985, he came to Worcester for the week-long Stanley Kunitz Poetry Festival in honor of his 80th birthday and on the last day of the festival, Kunitz decided to try once more to find the house on Woodford Street. Greg and Carol Stockmal, who had bought the house in 1979, found Kunitz and his entourage standing in front of their home. They invited everyone in, and when Kunitz mentioned a pear tree he and his mother had planted in the backyard, Greg told him one still grew there, and it produced abundant fruit. The 20 year friendship between the Stockmals and Kunitz and his wife, artist/poet Elise Asher, began on that day. The Stanley Kunitz-Stockmal Collection consists of materials collected by Greg and Carol Stockmal and includes: correspondence from Kunitz to the Stockmals; books signed and inscribed by Kunitz and his wife, poet/artist Elise Asher; audiovisual material on Kunitz; photographs of Kunitz and the Stockmals; and newspaper clippings and other articles on Kunitz collected by the Stockmals

The Vehicle, Spring 1975

Vol. 17, No. 1 Table of Contents Fiction CurrentsTed Baldwinpage 5 A Rat in the TablaStanley Guillpage 14 The Birthday VisitCindy Russellpage 25 Poetry Dance of the LoonsDarlene Sourilepage 11 Ne Psalms PasDarlene Sourilepage 12 eulogy to a roseDarlene Sourilepage 13 FrictionLou Ann Hazelwoodpage 20 On My Grandmother\u27s DeathLou Ann Hazelwoodpage 21 (haiku)Stanley Guillpage 35 a love poem (by approximation)Ted Baldwinpage 37 WoundTed Baldwinpage 38 UntitledBarbara Ann Robinsonpage 40 Tundra FoxKay Murphypage 41 Another Wednesday NightKay Murphypage 42 Art Robb Brenneckecover Stanley Guillpage 4, 36, 43 Greg Shoulderspage 22, 23, 24https://thekeep.eiu.edu/vehicle/1032/thumbnail.jp

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Recent Advances Clarifying the Structure and Function of Plant Apyrases (Nucleoside Triphosphate Diphosphohydrolases).

Studies implicating an important role for apyrase (NTPDase) enzymes in plant growth and development began appearing in the literature more than three decades ago. After early studies primarily in potato, Arabidopsis and legumes, especially important discoveries that advanced an understanding of the biochemistry, structure and function of these enzymes have been published in the last half-dozen years, revealing that they carry out key functions in diverse other plants. These recent discoveries about plant apyrases include, among others, novel findings on its crystal structures, its biochemistry, its roles in plant stress responses and its induction of major changes in gene expression when its expression is suppressed or enhanced. This review will describe and discuss these recent advances and the major questions about plant apyrases that remain unanswered

Project Columbiad: Reestablishment of human presence on the Moon

In response to the Report of the Advisory Committee on the future of the U.S. Space Program and a request from NASA's Exploration Office, the MIT Hunsaker Aerospace Corporation (HAC) conducted a feasibility study, known as Project Columbiad, on reestablishing human presence on the Moon before the year 2000. The mission criteria established were to transport a four person crew to the lunar surface at any latitude and back to Earth with a 14-28 day stay on the lunar surface. Safety followed by cost of the Columbiad Mission were the top level priorities of HAC. The resulting design has a precursor mission that emplaces the required surface payloads before the piloted mission arrives. Both the precursor and piloted missions require two National Launch System (NLS) launches. Both the precursor and piloted missions have an Earth orbit rendezvous (EOR) with a direct transit to the Moon post-EOR. The piloted mission returns to Earth via a direct transit. Included among the surface payloads preemplaced are a habitat, solar power plant (including fuel cells for the lunar night), lunar rover, and mecanisms used to cover the habitat with regolith (lunar soil) in order to protect the crew members from severe solar flare radiation

Treating triple negative breast cancer cells with erlotinib plus a select antioxidant overcomes drug resistance by targeting cancer cell heterogeneity

Among breast cancer patients, those diagnosed with the triple-negative breast cancer (TNBC) subtype have the worst prog-nosis. TNBC does not express estrogen receptor-alpha, progesterone receptor, or the HER2 oncogene; therefore, TNBC lacks targets for molecularly-guided therapies. The concept that EGFR oncogene inhibitor drugs could be used as targeted treatment against TNBC has been put forth based on estimates that 30-60% of TNBC express high levels of EGFR. However, results from clinical trials testing EGFR inhibitors, alone or in combination with cytotoxic chemotherapy, did not improve patient outcomes. Results herein offer an explanation as to why EGFR inhibitors failed TNBC patients and support how combining a select antioxidant and an EGFR-specific small molecule kinase inhibitor (SMKI) could be an effective, novel therapeutic strategy. Treatment with CAT-SKL-a re-engineered protein form of the antioxidant enzyme catalase-inhibited cancer stem-like cells (CSCs), and treatment with the EGFR-specific SMKI erlotinib inhibited non-CSCs. Thus, combining the antioxidant CAT-SKL with erlotinib targeted both CSCs and bulk cancer cells in cultures of EGFR-expressing TNBC-derived cells. We also report evidence that the mechanism for CAT-SKL inhibition of CSCs may depend on antioxidant-induced downregulation of a short alternative mRNA splicing variant of the methyl-CpG binding domain 2 gene, isoform MBD2c

Television news and the symbolic criminalisation of young people

This is an Author's Accepted Manuscript of an article published in Journalism Studies, 9(1), 75 - 90, 2008, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/14616700701768105.This essay combines quantitative and qualitative analysis of six UK television news programmes. It seeks to analyse the representation of young people within broadcast news provision at a time when media representations, political discourse and policy making generally appear to be invoking young people as something of a folk devil or a locus for moral panics. The quantitative analysis examines the frequency with which young people appear as main actors across a range of different subjects and analyses the role of young people as news sources. It finds a strong correlation between young people and violent crime. A qualitative analysis of four “special reports” or backgrounders on channel Five's Five News explores the representation of young people in more detail, paying attention to contradictions and tensions in the reports, the role of statistics in crime reporting, the role of victims of crime and the tensions between conflicting news frames.Arts and Humanities Research Counci