3 research outputs found
Animal models for COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological
agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection
caused by the introduction of a novel coronavirus into humans late in 2019 (frst
detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread
to 215 countries, has infected more than 30 million people and has caused more than
950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there
is an urgent need to develop therapeutic agents and vaccines to mitigate the current
pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World
Health Organization (WHO) assembled an international panel to develop animal
models for COVID-19 to accelerate the testing of vaccines and therapeutic agents.
Here we summarize the fndings to date and provides relevant information for
preclinical testing of vaccine candidates and therapeutic agents for COVID-19.info:eu-repo/semantics/acceptedVersio