4,298 research outputs found

    A Large Deviation Rate and Central Limit Theorem for Horton Ratios

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    Although originating in hydrology, the classical Horton analysis is based on a geometric progression that is widely used in the empirical analysis of branching patterns found in biology, atmospheric science, plant pathology, etc., and more recently in tree register allocation in computer science. The main results of this paper are a large deviation rate and a central limit theorem for Horton bifurcation ratios in a standard network model. The methods are largely self-contained. In particular, derivations of some previously known results of the theory are indicated along the way

    Winston Churchill versus Germany| A chronological interpretation, 1932-1940

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    Hear My Dollies\u27 Prayer

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    https://digitalcommons.library.umaine.edu/mmb-vp/2872/thumbnail.jp

    When I Dream of Home and Mother-And of You

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    https://digitalcommons.library.umaine.edu/mmb-vp/5917/thumbnail.jp

    Multiracial versus Collective Black Categories

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    Current census debates in Brazil surrounding Brazilian race categories center on two contrasting proposals: the adoption of the multiracial moreno term vs. the use of the collective black classification negro. Those proposing the former base their argument on the right to self-classify according to one’s own sense of identity. Proponents of the negro category contend that it would be most efficient for redressing racial discrimination. We examine the meaning and saliency of these categories and explore the possible consequences of their adoption. Using national survey data, we demonstrate how education, age, color, sex and local racial composition structure the choices of moreno and negro over official census terms. Findings include a negative correlation between education and the choice of moreno, while the opposite is true for negro. In addition, an age effect on both categories suggests a popular shift in racial labeling away from official census terms. We note that similar issues structure current census debates in the USA

    The Long-Term Cost to the UK NHS and Social Services of Different Durations of IV Thiamine (Vitamin B1) for Chronic Alcohol Misusers with Symptoms of Wernicke's Encephalopathy Presenting at the Emergency Department.

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    BACKGROUND: Wernicke's encephalopathy (WE) is an acute neuropsychiatric condition caused by depleted intracellular thiamine, most commonly arising in chronic alcohol misusers, who may present to emergency departments (EDs) for a variety of reasons. Guidelines recommend a minimum 5-day course of intravenous (IV) thiamine in at-risk patients unless WE can be excluded. OBJECTIVE: To estimate the cost impact on the UK public sector (NHS and social services) of a 5-day course of IV thiamine, vs a 2- and 10-day course, in harmful or dependent drinkers presenting to EDs. METHODS: A Markov chain model compared expected prognosis of patients under alternative admission strategies over 35 years. Model inputs were derived from a prospective cohort study, expert opinion via structured elicitation and NHS costing databases. Costs (2012/2013 price year) were discounted at 3.5 %. RESULTS: Increasing treatment from 2 to 5 days increased acute care costs but reduced the probability of disease progression and thus reduced the expected net costs by GBP87,000 per patient (95 % confidence interval GBP19,300 to GBP172,300) over 35 years. CONCLUSIONS: Increasing length of stay to optimize IV thiamine replacement will place additional strain on acute care but has potential UK public sector cost savings. Social services and the NHS should explore collaborations to realise both the health benefits to patients and savings to the public purse.This study was funded by Archimedes UK Pharma Ltd, the manufacturer of Pabrinex®. Hayward Medical Communications provided editorial and writing support during manuscript development.This is the final version of the article. It was first available from Springer via http://dx.doi.org/10.1007/s40258-015-0214-
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