78 research outputs found
The Effect of Opioid Receptor Blockade on the Neural Processing of Thermal Stimuli
The endogenous opioid system represents one of the principal systems in the modulation of pain. This has been demonstrated in studies of placebo analgesia and stress-induced analgesia, where anti-nociceptive activity triggered by pain itself or by cognitive states is blocked by opioid antagonists. The aim of this study was to characterize the effect of opioid receptor blockade on the physiological processing of painful thermal stimulation in the absence of cognitive manipulation. We therefore measured BOLD (blood oxygen level dependent) signal responses and intensity ratings to non-painful and painful thermal stimuli in a double-blind, cross-over design using the opioid receptor antagonist naloxone. On the behavioral level, we observed an increase in intensity ratings under naloxone due mainly to a difference in the non-painful stimuli. On the neural level, painful thermal stimulation was associated with a negative BOLD signal within the pregenual anterior cingulate cortex, and this deactivation was abolished by naloxone
ConectCat : aplicación web : fiestas locales y otros servicios y puntos de interés en Cataluña
Aplicación web basada en mapas interactivos y timeline. Permite visualizar las fiestas locales asà como otros servicios y puntos de interés de Cataluña
Harvesting Season and Botanical Origin Interferes in Production and Nutritional Composition of Bee Pollen
Inhibition of microglial activation in rats attenuates paraventricular nucleus inflammation in Gαi 2
Consumption and Brood Rearing by Caged Honeybees Fed Pollen Substitutes Fortified with Various Sugars
Brood Rearing and Food Consumption by Honeybee Colonies Fed Pollen Substitutes Supplemented with Starch-Encapsulated Pollen Extracts
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