390 research outputs found
Systematic effects from an ambient-temperature, continuously-rotating half-wave plate
We present an evaluation of systematic effects associated with a
continuously-rotating, ambient-temperature half-wave plate (HWP) based on two
seasons of data from the Atacama B-Mode Search (ABS) experiment located in the
Atacama Desert of Chile. The ABS experiment is a microwave telescope sensitive
at 145 GHz. Here we present our in-field evaluation of celestial (CMB plus
galactic foreground) temperature-to-polarization leakage. We decompose the
leakage into scalar, dipole, and quadrupole leakage terms. We report a scalar
leakage of ~0.01%, consistent with model expectations and an order of magnitude
smaller than other CMB experiments have reported. No significant dipole or
quadrupole terms are detected; we constrain each to be <0.07% (95% confidence),
limited by statistical uncertainty in our measurement. Dipole and quadrupole
leakage at this level lead to systematic error on r<0.01 before any mitigation
due to scan cross-linking or boresight rotation. The measured scalar leakage
and the theoretical level of dipole and quadrupole leakage produce systematic
error of r<0.001 for the ABS survey and focal-plane layout before any data
correction such as so-called deprojection. This demonstrates that ABS achieves
significant beam systematic error mitigation from its HWP and shows the promise
of continuously-rotating HWPs for future experiments.Comment: 11 pages, 8 figures; revision to submitted version, Fig. 5 and Eqs.
(14) and (15) corrected; added Fig. 9 and description, text revisions for
clarification, Fig. 5 revised for better calibration, corrected labeling
errors and plotting bugs in Fig. 3, 4, and Eq. (14) and (15
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Brines formed by multi-salt deliquescence
The FY05 Waste Package Environment testing program at Lawrence Livermore National Laboratory focused on determining the temperature, relative humidity, and solution compositions of brines formed due to the deliquescence of NaCl-KNO{sub 3}-NaNO{sub 3} and NaCl-KNO{sub 3}-NaNO{sub 3}-Ca(NO{sub 3}){sub 2} salt mixtures. Understanding the physical and chemical behavior of these brines is important because they define conditions under which brines may react with waste canister surfaces. Boiling point experiments show that NaCl-KNO{sub 3}-NaNO{sub 3} and NaCl-KNO{sub 3}-NaNO{sub 3}-Ca(NO{sub 3}){sub 2} salt mixtures form brines that transform to hydrous melts that do not truly 'dry out' until temperatures exceed 300 and 400 C, respectively. Thus a conducting solution is present for these salt assemblages over the thermal history of the repository. The corresponding brines form at lower relative humidity at higher temperatures. The NaCl-KNO{sub 3}-NaNO{sub 3} salt mixture has a mutual deliquescence relative humidity (MDRH) of 25.9% at 120 C and 10.8% at 180 C. Similarly, the KNO{sub 3}-NaNO{sub 3} salt mixture has MDRH of 26.4% at 120 C and 20.0% at 150 C. The KNO{sub 3}-NaNO{sub 3} salt mixture salts also absorb some water (but do not appear to deliquesce) at 180 C and thus may also contribute to the transfer of electrons at interface between dust and the waste package surface. There is no experimental evidence to suggest that these brines will degas and form less deliquescent salt assemblages. Ammonium present in atmospheric and tunnel dust (as the chloride, nitrate, or sulfate) will readily decompose in the initial heating phase of the repository, and will affect subsequent behavior of the remaining salt mixture only through the removal of a stoichiometric equivalent of one or more anions. Although K-Na-NO{sub 3}-Cl brines form at high temperature and low relative humidity, these brines are dominated by nitrate, which is known to inhibit corrosion at lower temperature. Nitrate to chloride ratios of the NaCl-KNO{sub 3}-NaNO{sub 3} salt mixture are about NO{sub 3}:Cl = 19:1. The role of nitrate on corrosion at higher temperatures is addressed in a companion report (Dixit et al., 2005)
Modulation of CMB polarization with a warm rapidly-rotating half-wave plate on the Atacama B-Mode Search (ABS) instrument
We evaluate the modulation of Cosmic Microwave Background (CMB) polarization
using a rapidly-rotating, half-wave plate (HWP) on the Atacama B-Mode Search
(ABS). After demodulating the time-ordered-data (TOD), we find a significant
reduction of atmospheric fluctuations. The demodulated TOD is stable on time
scales of 500-1000 seconds, corresponding to frequencies of 1-2 mHz. This
facilitates recovery of cosmological information at large angular scales, which
are typically available only from balloon-borne or satellite experiments. This
technique also achieves a sensitive measurement of celestial polarization
without differencing the TOD of paired detectors sensitive to two orthogonal
linear polarizations. This is the first demonstration of the ability to remove
atmospheric contamination at these levels from a ground-based platform using a
rapidly-rotating HWP.Comment: 8 pages, 8 figures, Published in RSI under the title "Modulation of
cosmic microwave background polarization with a warm rapidly rotating
half-wave plate on the Atacama B-Mode Search instrument.
New Measurements of Fine-Scale CMB Polarization Power Spectra from CAPMAP at Both 40 and 90 GHz
We present new measurements of the cosmic microwave background (CMB)
polarization from the final season of the Cosmic Anisotropy Polarization MAPper
(CAPMAP). The data set was obtained in winter 2004-2005 with the 7 m antenna in
Crawford Hill, New Jersey, from 12 W-band (84-100 GHz) and 4 Q-band (36-45 GHz)
correlation polarimeters with 3.3' and 6.5' beamsizes, respectively. After
selection criteria were applied, 956 (939) hours of data survived for analysis
of W-band (Q-band) data. Two independent and complementary pipelines produced
results in excellent agreement with each other. A broad suite of null tests as
well as extensive simulations showed that systematic errors were minimal, and a
comparison of the W-band and Q-band sky maps revealed no contamination from
galactic foregrounds. We report the E-mode and B-mode power spectra in 7 bands
in the range 200 < l < 3000, extending the range of previous measurements to
higher l. The E-mode spectrum, which is detected at 11 sigma significance, is
in agreement with cosmological predictions and with previous work at other
frequencies and angular resolutions. The BB power spectrum provides one of the
best limits to date on B-mode power at 4.8 uK^2 (95% confidence).Comment: 19 pages, 17 figures, 2 tables, submitted to Ap
Gene profile analysis of osteoblast genes differentially regulated by histone deacetylase inhibitors
<p>Abstract</p> <p>Background</p> <p>Osteoblast differentiation requires the coordinated stepwise expression of multiple genes. Histone deacetylase inhibitors (HDIs) accelerate the osteoblast differentiation process by blocking the activity of histone deacetylases (HDACs), which alter gene expression by modifying chromatin structure. We previously demonstrated that HDIs and HDAC3 shRNAs accelerate matrix mineralization and the expression of osteoblast maturation genes (e.g. alkaline phosphatase, osteocalcin). Identifying other genes that are differentially regulated by HDIs might identify new pathways that contribute to osteoblast differentiation.</p> <p>Results</p> <p>To identify other osteoblast genes that are altered early by HDIs, we incubated MC3T3-E1 preosteoblasts with HDIs (trichostatin A, MS-275, or valproic acid) for 18 hours in osteogenic conditions. The promotion of osteoblast differentiation by HDIs in this experiment was confirmed by osteogenic assays. Gene expression profiles relative to vehicle-treated cells were assessed by microarray analysis with Affymetrix GeneChip 430 2.0 arrays. The regulation of several genes by HDIs in MC3T3-E1 cells and primary osteoblasts was verified by quantitative real-time PCR. Nine genes were differentially regulated by at least two-fold after exposure to each of the three HDIs and six were verified by PCR in osteoblasts. Four of the verified genes (solute carrier family 9 isoform 3 regulator 1 (Slc9a3r1), sorbitol dehydrogenase 1, a kinase anchor protein, and glutathione S-transferase alpha 4) were induced. Two genes (proteasome subunit, beta type 10 and adaptor-related protein complex AP-4 sigma 1) were suppressed. We also identified eight growth factors and growth factor receptor genes that are significantly altered by each of the HDIs, including Frizzled related proteins 1 and 4, which modulate the Wnt signaling pathway.</p> <p>Conclusion</p> <p>This study identifies osteoblast genes that are regulated early by HDIs and indicates pathways that might promote osteoblast maturation following HDI exposure. One gene whose upregulation following HDI treatment is consistent with this notion is Slc9a3r1. Also known as NHERF1, Slc9a3r1 is required for optimal bone density. Similarly, the regulation of Wnt receptor genes indicates that this crucial pathway in osteoblast development is also affected by HDIs. These data support the hypothesis that HDIs regulate the expression of genes that promote osteoblast differentiation and maturation.</p
Characterizing Atacama B-mode Search Detectors with a Half-Wave Plate
The Atacama B-Mode Search (ABS) instrument is a cryogenic (10 K)
crossed-Dragone telescope located at an elevation of 5190 m in the Atacama
Desert in Chile that observed for three seasons between February 2012 and
October 2014. ABS observed the Cosmic Microwave Background (CMB) at large
angular scales () to limit the B-mode polarization spectrum around
the primordial B-mode peak from inflationary gravity waves at .
The ABS focal plane consists of 480 transition-edge sensor (TES) bolometers.
They are coupled to orthogonal polarizations from a planar ortho-mode
transducer (OMT) and observe at 145 GHz. ABS employs an ambient-temperature,
rapidly rotating half-wave plate (HWP) to mitigate systematic effects and move
the signal band away from atmospheric noise, allowing for the recovery of
large angular scales. We discuss how the signal at the second harmonic of the
HWP rotation frequency can be used for data selection and for monitoring the
detector responsivities.Comment: 7 pages, 3 figures, conference proceedings submitted to the Journal
of Low Temperature Detector
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Boiling Temperature and Reversed Deliquescence Relative Humidity Measurements for Mineral Assemblages in the NaCl + NaNO3 + KNO3 + Ca(NO3)2 + H2O System
Boiling temperature measurements have been made at ambient pressure for saturated ternary solutions of NaCl + KNO{sub 3} + H{sub 2}O, NaNO{sub 3} + KNO{sub 3} + H{sub 2}O, and NaCl + Ca(NO{sub 3}){sub 2} + H{sub 2}O over the full composition range, along with those of the single salt systems. Boiling temperatures were also measured for the four component NaCl + NaNO{sub 3} + KNO{sub 3} + H{sub 2}O and five component NaCl + NaNO{sub 3} + KNO{sub 3} + Ca(NO{sub 3}){sub 2} + H{sub 2}O mixtures, where the solute mole fraction of Ca(NO{sub 3}){sub 2}, x(Ca(NO{sub 3}){sub 2}), was varied between 0 and 0.25. The maximum boiling temperature found for the NaCl + KNO{sub 3} + H{sub 2}O system is {approx} 134.9 C; for the NaNO{sub 3} + KNO{sub 3} + H{sub 2}O system is {approx} 165.1 C at x(NaNO{sub 3}) {approx} 0.46 and x(KNO{sub 3}) {approx} 0.54; and for the NaCl + Ca(NO{sub 3}){sub 2} + H{sub 2}O system is 164.7 {+-} 0.6 C at x(NaCl) {approx} 0.25 and x(Ca(NO{sub 3}){sub 2}) {approx} 0.75. The NaCl + NaNO{sub 3} + KNO{sub 3} + Ca(NO{sub 3}){sub 2} + H{sub 2}O system forms molten salts below their maximum boiling temperatures, and the temperatures corresponding to the cessation of boiling (dry out temperatures) of these liquid mixtures were determined. These dry out temperatures range from {approx} 300 C when x(Ca(NO{sub 3}){sub 2}) = 0 to {ge} 400 C when x(Ca(NO{sub 3}){sub 2}) = 0.20 and 0.25. Mutual deliquescence/efflorescence relative humidity (MDRH/MERH) measurements were also made for the NaNO{sub 3} + KNO{sub 3} and NaCl + NaNO{sub 3} + KNO{sub 3} salt mixture from 120 to 180 C at ambient pressure. The NaNO{sub 3} and NaCl + NaNO{sub 3} + KNO{sub 3} salt mixture has a MDRH of 26.4% at 120 C and 20.0% at 150 C. This salt mixture also absorbs water at 180 C, which is higher than expected from the boiling temperature experiments. The NaCl + NaNO{sub 3} + KNO{sub 3} salt mixture was found to have a MDRH of 25.9% at 120 C and 10.5% at 180 C. The investigated mixture compositions correspond to some of the major mineral assemblages that are predicted to control brine composition due to the deliquescence of salts formed in dust deposited on waste canisters in the proposed nuclear repository at Yucca Mountain, Nevada
The QUIET Instrument
The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the
Cosmic Microwave Background, targeting the imprint of inflationary
gravitational waves at large angular scales (~ 1 degree). Between 2008 October
and 2010 December, two independent receiver arrays were deployed sequentially
on a 1.4 m side-fed Dragonian telescope. The polarimeters which form the focal
planes use a highly compact design based on High Electron Mobility Transistors
(HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U,
and I in a single module. The 17-element Q-band polarimeter array, with a
central frequency of 43.1 GHz, has the best sensitivity (69 uK sqrt(s)) and the
lowest instrumental systematic errors ever achieved in this band, contributing
to the tensor-to-scalar ratio at r < 0.1. The 84-element W-band polarimeter
array has a sensitivity of 87 uK sqrt(s) at a central frequency of 94.5 GHz. It
has the lowest systematic errors to date, contributing at r < 0.01. The two
arrays together cover multipoles in the range l= 25-975. These are the largest
HEMT-based arrays deployed to date. This article describes the design,
calibration, performance of, and sources of systematic error for the
instrument
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