Garnet: a middleware architecture for distributing data streams originating in wireless sensor networks

We present an architectural framework, Garnet, which provides a data stream centric abstraction to encourage the manipulation and exploitation of data generated in sensor networks. By providing middleware services to allow mutually-unaware applications to manipulate sensor behaviour, a scalable, extensible platform is provided. We focus on sensor networks with transmit and receive capabilities as this combination poses greater challenges for managing and distributing sensed data. Our approach allows simple and sophisticated sensors to coexist, and allows data consumers to be mutually unaware of each other This also promotes the use of middleware services to mediate among consumers with potentially conflicting demands for shared data. Garnet has been implemented in Java, and we report on our progress to date and outline some likely scenarios where the use of our distributed architecture and accompanying middleware support enhances the task of sharing data in sensor network environments

Neural mechanisms of reactivation-induced updating that enhance and distort memory

We remember a considerable number of personal experiences because we are frequently reminded of them, a process known as memory reactivation. Although memory reactivation helps to stabilize and update memories, reactivation may also introduce distortions if novel information becomes incorporated with memory. Here we used functional magnetic resonance imaging (fMRI) to investigate the neural mechanisms mediating reactivation-induced updating in memory for events experienced during a museum tour. During scanning, participants were shown target photographs to reactivate memories from the museum tour followed by a novel lure photograph from an alternate tour. Later, participants were presented with target and lure photographs and asked to determine whether the photographs showed a stop they visited during the tour. We used a subsequent memory analysis to examine neural recruitment during reactivation that was associated with later true and false memories. We predicted that the quality of reactivation, as determined by online ratings of subjective recollection, would increase subsequent true memories but also facilitate incorporation of the lure photograph, thereby increasing subsequent false memories. The fMRI results revealed that the quality of reactivation modulated subsequent true and false memories via recruitment of left posterior parahippocampal, bilateral retrosplenial, and bilateral posterior inferior parietal cortices. However, the timing of neural recruitment and the way in which memories were reactivated contributed to differences in whether memory reactivation led to distortions or not. These data reveal the neural mechanisms recruited during memory reactivation that modify how memories will be subsequently retrieved, supporting the flexible and dynamic aspects of memory

Process for preparing polyimide adhesives

High bonding strengths are obtained for metals and fiber-reinforced organic resin composites with no significant loss in thermo-oxidative stability of the adhesive resin

Mid-morning Break and Poster Sessions: Application of the Theory of Planned Behaviour within School-Based Prevention Programs for Adolescent Gambling

The theory of planned behaviour (TPB) and the concept of anticipatory negative emotions have attracted considerable research attention in the formulation of effective preventive interventions. This approach has identified several key constructs (i.e., attitudes, subjective norms, perceptions of control, anticipation of negative emotions) as valid predictors of gambling intentions and behaviour. However, no empirical investigation has utilized these constructs in the design or evaluation of a youth problem gambling prevention initiative. Objectives. The current research aims to assess the effects of a prevention video on gambling-related attitudes, subjective norms, control perceptions, anticipated negative emotions, and intentions. The video focuses on a problem gambler’s testimonial and includes dramatic vignettes depicting the potential risks and consequences associated with excessive gambling. Methodology. A sample of 328 high school students were randomly assigned to either a video or control group. Participants were assessed at pre- and post-intervention. Results. Preliminary results reveal that the video produced changes in students’: (i) attitudes towards; (ii) perceptions of control over and; (iii) negative anticipatory emotions following excessive participation in gambling. Individuals receiving the intervention were observed to have a significant decreases in positive attitudes toward gambling as well as perceptions of control over gambling, and a significant increase in their anticipation of negative emotions for becoming over-involved in gambling. Conclusions. Positive effects of the video were found. Recommendations for future research are discussed

SOME REMARKS ON THE SMARANDACHE FUNCTION

Remarks on a Function in the Number Theory

Southwest Research Institute assistance to NASA in biomedical areas of the technology utilization program Quarterly progress report, 1 Jul. - 30 Sep. 1968

Southwest Research Institute activites in NASA technology utilization program for biomedical use, 1 Jul. - 30 Sep. 196

Southwest Research Institute assistance to NASA in biomedical areas of the technology utilization program Cumulative quarterly report, 1 Apr. - 30 Jun. 1968

Biomedical applications of NASA science and technolog

Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies

Mandelate racemase (MR), a member of the enolase superfamily, catalyzes the Mg2+-dependent interconversion of the enantiomers of mandelate. Several α-keto acids are modest competitive inhibitors of MR [e.g., mesoxalate (Ki = 1.8 ± 0.3 mM) and 3-fluoropyruvate (Ki = 1.3 ± 0.1 mM)], but, surprisingly, 3-hydroxypyruvate (3-HP) is an irreversible, time-dependent inhibitor (kinact/KI = 83 ± 8 M–1 s–1). Protection from inactivation by the competitive inhibitor benzohydroxamate, trypsinolysis and electrospray ionization tandem mass spectrometry analyses, and X-ray crystallographic studies reveal that 3-HP undergoes Schiff-base formation with Lys 166 at the active site, followed by formation of an aldehyde/enol(ate) adduct. Such a reaction is unprecedented in the enolase superfamily and may be a relic of an activity possessed by a promiscuous progenitor enzyme. The ability of MR to form and deprotonate a Schiff-base intermediate furnishes a previously unrecognized mechanistic link to other α/β-barrel enzymes utilizing Schiff-base chemistry and is in accord with the sequence- and structure-based hypothesis that members of the metal-dependent enolase superfamily and the Schiff-base-forming N-acetylneuraminate lyase superfamily and aldolases share a common ancestor